Key Publications

Key publications by the group since 2012.

Library shelves full of books


Iris S S Ho, Amaya Azcoaga-Lorenzo, Ashley Akbari, Jim Davies, Kamlesh Khunti, Umesh T Kadam, Ronan A Lyons, Colin McCowan, Stewart W Mercer, Krishnarajah Nirantharakumar, Sophie Staniszewska and Bruce Guthrie Measuring multimorbidity in research: Delphi consensus study BMJ Medicine July 27 2022 doi: 10.1136/bmjmed-2022-000247


Anna WildingLuke MunfordBruce GuthrieEvangelos KontopantelisMatt SuttonFamily Doctor responses to changes in target stringency under financial incentivesJournal of Health Economics

Jonathan Stokes Peter Bower Bruce Guthrie Stewart W.Mercer Nigel Rice Andrew M.Ryan Matt SuttonCuts to local government spending, multimorbidity and health-related quality of life: A longitudinal ecological study in England: The Lancet Regional Health:


Ellen Stewart, Eddie Donaghy, Bruce Guthrie, David Henderson, Huayi Huang, Martyn Pickersgill, Harry HX Wang and Stewart Mercer: Transforming primary care in Scotland: a critical policy analysis: British Journal of General Practice 2022; 72 (719): 292-294.  DOI: 


Park, K-Y, Shin, J, Park, H-K, Kim, YM, Hwang, SY, Shin, J-H, Heo, R, Ryu, S & Mercer, SW 2022, 'Validity and reliability of a Korean version of the Consultation and Relational Empathy (CARE) measure', BMC Medical Education, vol. 22, no. 1, pp. 403.


Hubbard G, Grist F, Pope LM, Cunningham S, Maxwell M, Bennie M, Guthrie B, Mercer SW: Survey to identify research priorities for primary care in Scotland during and following the COVID-19 pandemic. BMJ Open. 2022 May 3;12(5):e056817. doi: 10.1136/bmjopen-2021-056817. PMID: 35504637


Shona J. Livingstone, Bruce Guthrie, Peter T. Donnan, Alexander Thompson & Daniel R. Morales: Predictive performance of a competing risk cardiovascular prediction tool CRISK compared to QRISK3 in older people and those with comorbidity: population cohort study BMC Medicine volume 20, Article number: 152 (2022) 


Adam L Gordon, Caroline Rick, Ed Juszczak, Alan Montgomery, Rob Howard, Bruce Guthrie, Wei Shen Lim, Susan Shenkin, Paul Leighton, Philip M Bath, the PROTECT-CH Triallists The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure BGS Age and Ageing Volume 51, Issue 3 March 2022


Hodgkins P, McMinn M, Shah A, Reed MJ, Mercer S, Guthrie B: Unscheduled care pathways in patients with myocardial infarction in Scotland British Medical Journal - Heart- March 2022


Ho, IS-S, Azcoaga-Lorenzo, A, Akbari, A, Davies, J, Hodgins, P, Khunti, K, Kadam, U, Lyons, R, McCowan, C, Mercer, SW, Nirantharakumar, K & Guthrie, B 2022, 'Variation in the estimated prevalence of multimorbidity: systematic review and meta-analysis of 193 international studies', BMJ Open, vol. 12, no. 4, pp. e057017.


Ho, I, Azcoaga-Lorenzo, A, Akbari, A, Black, C, Davies, J, Hodgins, P, Khunti, K, Leicester, U, Lyons, RA, McGowan, C, Mercer, SW, Nirantharakumar, K & Guthrie, B 2021, 'Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies', The Lancet Public Health.  


Captieux R, Fleetwood K, Kennon B, Sattar N, Lindsay R, Guthrie B, Wild SH on behalf of the Scottish Diabetes Research Network epidemiology group. Epidemiology of type 2 diabetes remission in Scotland in 2019: a cross-sectional population-based study. PLoS Medicine 2021: 18(11): e1003828


Captieux M, Prigge R, Wild S, Guthrie B. Defining remission of type 2 diabetes in research studies: A systematic scoping review. PLOS Medicine 2020;17:e1003396.


Burton, JK, Bayne, G, Evans, C, Garbe, F, Gorman, D, Lothian, P, McCormick, D, Lothian, P, Stevenson, J, Swietlik, S, Templeton, KE, Tranter, M, Willocks, L & Guthrie, B 2020, 'Evolution and impact of COVID-19 outbreaks in care-homes: population analysis in 189 care-homes in one geographic region', Lancet Healthy Longevity.&nbsp.


He, J, Morales, DR & Guthrie, B 2020, 'Exclusion rates in randomized-controlled trials of treatments for physical conditions: a systematic review ', Trials, vol. 21, no. 228.


Santiago VH, Davey PG, Nathwani D, Marwick C, Guthrie B.  Impact of a primary care antimicrobial stewardship intervention on resistance in coliform bacteraemia. PLoS Medicine 2019;16:e1002825


Minchin, M, Roland, M, Richardson, J, Rowark, S & Guthrie, B 2018, 'Quality of Care in the United Kingdom after Removal of Financial Incentives', New England Journal of Medicine, vol. 379, no. 10, pp. 948-957.  2018


Salisbury, C, Man, M-S, Bower, P, Guthrie, B, Chaplin, K, Gaunt, DM, Brookes, S, Fitzpatrick, B, Gardner, C, Hollinghurst, S, Lee, V, McLeod, J, Mann, C, Moffat, KR & Mercer, SW 2018, 'Management of multimorbidity using a patient-centred care model', The Lancet, vol. 392, no. 10141, pp. 41-50.


Dreischulte, T, Donnan, P, Grant, A, Hapca, A, McCowan, C & Guthrie, B 2016, 'Safer Prescribing: A Trial of Education, Informatics, and Financial Incentives', New England Journal of Medicine, vol. 374, no. 11, pp. 1053-1064.


Guthrie, B, Kavanagh, K, Robertson, C, Barnett, K, Treweek, S, Petrie, D, Ritchie, LD & Bennie, M 2016, 'Data feedback and behavioural change intervention to improve primary care prescribing safety (EFIPPS)', British Medical Journal, vol. 354, pp. 1-9.


Mercer, SW, Higgins, M, Bikker, AM, Fitzpatrick, B, McConnachie, A, Lloyd, SM, Little, P & Watt, GCM 2016, 'General Practitioners Empathy and Health Outcomes: A Prospective Observational Study of Consultations in Areas of High and Low Deprivation', The Annals of Family Medicine, vol. 14, no. 2, pp. 117-124.


W. Mercer, S, Fitzpatrick, B, Guthrie, B, Fenwick, E, Grieve, E, Lawson, K, Boyer, N, McConnachie, A, Lloyd, SM, O'Brien, R, Watt, GCM & Wyke, S 2016, 'The care plus study - a whole system intervention to improve quality of life of primary care patients with multimorbidity in areas of high socioeconomic deprivation', BMC Medicine, vol. 14, pp. 1-10.


Guthrie, B, Makubate, B, Hernandez Santiago, V & Dreischulte, T 2015, 'The rising tide of polypharmacy and drug-drug interactions', BMC Medicine, vol. 13.


Wang HHX, Wang JJ, Wong SYS, Wong MCS, Zhou ZH, Li FJ, Wang PX, Xu L, Griffiths SM, Mercer SW. Epidemiology of multimorbidity and implications for equitable healthcare: Cross-sectional survey among 162,464 community household residents in southern China. BMC Medicine 2014,12:188


Barnett, K, Mercer, SW, Norbury, M, Watt, G, Wyke, S & Guthrie, B 2012, 'Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study', The Lancet, vol. 380, no. 9836, pp. 37-43.


Guthrie, B, Payne, K, Alderson, P, McMurdo, MET & Mercer, SW 2012, 'Adapting clinical guidelines to take account of multimorbidity', British Medical Journal, vol. 345, no. oct04, pp. e6341-e6341.








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