Precision Medicine Doctoral Training Programme

23/24 Projects

Listing of available projects for 23/24 entry.

Applications for all projects must be submitted via the University of Edinburgh's Degree FinderPlease include a CV with your application. Your CV can be uploaded to the Research Proposal section of your application.

 

UNIVERSITY OF GLASGOW PROJECTS

University of Glasgow Lead projects can be found here.

 

UNIVERSITY OF EDINBURGH PROJECTS

PROJECT TITLE SUPERVISOR
Analysis of Parkinson’s speech patterns for digital biomarker discovery and intervention assessment Dr Saturnino Luz       
Blood flow and solute transport in human placental microvasculature: an in silico approach to stratifying pregnancy pathologies Dr Timm Krüger
Could disrupted functional connectivity between the hippocampus and the prefrontal cortex be an early marker of vascular cognitive impairment in dementia? Dr Jian Gan                                                                      
Development of a machine learning method to automatically quantify calcified intracranial atheroma on CT imaging and assess risk of future neurovascular disease in a national dataset Dr Grant Mair   
DNA nanotechnology for multiplexed quantification of steroid hormones and other biomarkers: building a new tool to advance animal and human health Dr Katherine Dunn                                      
Endothelial cell extracellular vesicles in cerebral small vessel disease Prof Joanna Wardlaw          
Generation of a multivariate stratification model to predict Trametinib-sensitive low-grade serous ovarian cancer tumours Dr Alex von Kriegsheim
Genomic characterisation of multidrug-resistant septicaemia-causing Klebsiella pneumoniae to inform patient care and infection control Dr Prerna Vohra
High-throughput single neuron resolution mapping of connecopathies in animal models of neurodevelopmental disorders Dr Sara Wade
Machine learning to understand the impact of epilepsy on functional outcomes Dr Javier Escudero Rodriguez
Metabolomic analysis of adipose tissue in Drosophila models of human obesity Dr Neha Agrawal
Modelling the role of defective miRNA biogenesis in pediatric tumours Dr Sara Macias
Multiomics approach to determine the role of IL17 on liver regenerative cholangiocytes in chronic liver diseases Dr Wei-Yu Lu  
New insights into longitudinal visceral pain symptom trajectories using clinical lab tests, self-reports, and wearable sensors Dr Thanasis Tsanas
Optimising treatment for scoliosis correction using computational modelling and data analysis Prof Pankaj Pankaj      
Optimized Deep Brain Stimulation for SYNGAP1 Epileptic Encephalopathy Dr Alfredo Gonzalez-Sulser                   
Realising the potential of retinal image analysis with AI methods for the prediction of eye/brain conditions in the primary care setting Prof Miguel Bernabeu        
Studying biological aging to understand and prevent premature mortality in mental illness Dr Jasmin Wertz
The synaptic basis of Cognitive reserve in Alzheimer's disease  Dr Patricio Opazo
Uncovering the molecular basis of how germline mutations of the synaptonemal complex lead to human infertility Dr Owen Davies
Understanding the effect of mutations on cell behaviour in blood disorders through mathematical modelling and computational analysis Dr Linus Schumacher
Using liquid biopsy to understand organ injury in critical illness

Dr Simon Biddie

Using single transcriptomic and genetic manipulation to investigate the cellular interaction in preneoplastic cell development niche  Dr Yi Feng       

 

iCASE PROJECTS

MRC’s iCASE awards provide students with experience of collaborative research with a non‐academic partner, enabling the student to spend a period of time with the non-academic partner (usually no less than three months over the lifetime of the PhD).

PROJECT TITLE SUPERVISOR
Endotyping neurodegeneration through the eye using multimodal retinal imaging Dr Tom MacGillivray  
Optical biosensors to multiplex immune cell function in infectious diseases Prof Marc Vendrell