CPHS Seminar: Understanding Serious Mental Illness and the Occurrence and Consequences of Ischaemic Heart Disease and Stroke

Title:                      Understanding Serious Mental Illness and the Occurrence and Consequences of Ischaemic Heart Disease and Stroke: A Routine Data Linkage Approach

Abstract:

People with a serious mental illness are known to have a substantially increased risk of ischaemic heart disease and stroke. However, in Scotland and elsewhere, we know less about how these associations vary by sociodemographic factors and over time. We also know relatively little about how serious mental illness affects outcomes and process of care of these key physical diseases. We have investigated these gaps in two large scale data linkage projects using national Scottish data, including general and psychiatric hospital admission data and death records. We will present findings from studies where we compared people with versus without hospitalisation for each of schizophrenia, bipolar disorder and depression to determine: (1) the incidence of stroke and ischaemic heart disease by time period and sociodemographic factors; and (2) differences in mortality and processes of care following each of stroke and myocardial infarction.

Speaker:            Caroline Jackson

Caroline is a Chancellor’s Fellow and non-clinical epidemiologist who completed her PhD at the University of Edinburgh and her MSc in Epidemiology at the London School of Hygiene and Tropical Medicine. With a background in epidemiology of chronic disease, Caroline’s current research interests include the interplay between mental and physical health. She is particularly interested in the role of mental health in the development of chronic physical disease and on the effect of co-morbid mental illness on clinical care for and outcomes of major physical diseases. Her research focuses on the use of large cohort studies, disease registers and routinely collected data. Prior to 2015 she worked at: the University of Queensland, Brisbane; the Scottish Collaboration for Public Health Research and Policy; and the University of Edinburgh, Division of Clinical Neurosciences.

Speaker:            Kelly Fleetwood

Kelly is a medical statistician working with Prof Bruce Guthrie. Her current work involves using data from UK Biobank to evaluate the relationships between depression and multimorbidity. She has recently completed a project with Prof Sarah Wild and Dr Caroline Jackson that used routine data to evaluate how major mental illness affects physical disease outcomes and quality of care amongst people with diabetes, stroke or myocardial infarction. Prior to joining the Usher Institute in 2017, Kelly worked in industry in both Scotland and Australia. During this time she provided statistical support to a broad range of projects in the life sciences, from gene expression studies to evaluations of the cost-effectiveness of new drugs.