Edinburgh Clinical Trials


REstart or STop Antithrombotics Randomised Trial (RESTART)

RESTART is a randomised controlled trial for adults surviving spontaneous intracerebral haemorrhage who had taken an antithrombotic drug (i.e. anticoagulant or antiplatelet medication) for the prevention of vaso-occlusive disease before the ICH.


Chief Investigator: Professor Rustam Al-Shahi Salman

Number and location of participating sites (by region/ country): UK 112 Active sites

EudraCT number: 2012-003190-26

ISRCTN number: 71907627


Funder: British Heart Foundation

Start and End Date of Grant Award: April 2013 to February 2021


Status: Currently recruiting                



Sponsor: University of Edinburgh and NHS Lothian ACCORD

CI: Professor Rustam Al-Shahi Salman

Trial Manager: Karen Innes, Room FU303E, Centre for Clinical Brain Sciences (CCBS), Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB


ECTU involvement: Database and randomisation service provision, statistics