Edinburgh Clinical Trials


Edinburgh and Lothian Virus Intervention Study in Kids: A randomised controlled trial of hypertonic saline nose drops in children with upper respiratory tract infections

To investigate whether the use of hypertonic saline (salt water) nose drops administered to children with symptoms consistent with acute viral Upper Respiratory Tract Infection (known as the ‘common cold’) reduces the duration of symptoms when compared to children managed using standard care.


Chief Investigator: Dr Sandeep Ramalingam

Number and location of participating sites / geographical scope (by region/ country):  Edinburgh - Royal Hospital for Children and Young People, Dundee - Ninewells Hospital, Wishaw - University Hospital Wishaw,  Kilmarnock - University Hospital Crosshouse

ISRCTN number: ClinicalTrials.gov NCT03463694   https://clinicaltrials.gov/ct2/show/NCT03463694


Elvis Kids Logo

Funder: Chief Scientist Office

Start and End date

Of grant award 01 June 2018 - 30 November 2021

Of recruitment November 2018 - 31 January 2023


Status: Recruiting        


Website links:  www.elviskids.co.uk


Sponsor: ACCORD http://www.accord.ed.ac.uk/

Chief Investigator: Dr Sandeep Ramalingam, Department of Laboratory Medicine, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA,

Email: Sandeep.ramalingam@nhslothian.scot.nhs.uk

Trial Manager: Mr Phillip Rayson, Edinburgh Clinical Trials Unit, Usher Institute, Level 2, BioQuarter 9, 9 Little France Road, Edinburgh, EH16 4UX, Email: elvis.kids@ed.ac.uk

Lead Research Nurse: Children's Clinical Research Facility, Royal Hospital for Sick Children, Edinburgh, Email: ElvisKids.Study@nhslothian.scot.nhs.uk



ECTU involvement: Trial management / Data base / Data Management / Admin support / Health Economics