Edinburgh Clinical Trials

UKCRC Studies

ECTU has a portfolio of adopted trials, which fall under the UK Clinical Research Collaboration registration number.

List of UKCRC studies

For further information please click on the study name.

Rheumatology / Orthopaedic:

DENS  (duration of external neck stabilisation)

LASER (assisted Staphylococcal eradication)

OPPORTUNITY (osteoarthritis in knees)

TOPaZ (Osteogenesis Imperfecta)

TRIO-Physio (physiotherapy vs knee replacement)

ZiPP (Paget's disease)


Health Economics:



4AT (triage tool for delirium)

LACI-2 (prevention of recurrent lacunar stroke)

MS-SMART (multiple sclerosis)

RESTART (spontaneous intracerebral haemorrhage)

MND-SMART (Motor Neurone Disease Systematic Multi-Arm Adaptive Randomised Trial)

CARE (symptomatic brain cavernoma)



DENS  (duration of external neck stabilisation)



Cardiac CARE (high-sensitivity cardiac troponin I)

DIAMOND (coronary atherosclerosis and PET CT)

DUAL ACS  (acute coronary syndrome)

EVoLVeD (early valve replacement)

HighSTEACS (high sensitivity Troponin)

HiSTORIC (high sensitivity Troponin)

PRE18FFIR (PET CT and myocardial infarction)

SALTIRE II (aortic stenosis)

SCOT-HEART 2 (computer tomography coronary angiography for the prevention of myocardial infarction)

TARGET-CTCA (using troponin to guide CTCA)


GEM (Crohn's disease)

MARVEL (ulcerative colitis)

PREdiCCt (crohn's disease flare up)

SPARE (Crohn's disease)

Mini MARVEL (ulcerative colitis)

MUSIC(ulcerative colitis and Crohn's disease)

Emergency/Critical Care:

A2B (alpha 2 agonists sedation agents)

RAPID CTCA (acute coronary syndrome)



PIB CAP (personalised antibiotic treatment for pneumonia) 

MucAct  (COPD)


HOT2 (renal transport - delayed graft function)


RESORP (recovery from acute pancreatitis)


ELVIS Kids (upper respiratory tract infection)


BRIDGE-IT  (emergency contraception)

CHOICE (cervical ripening at home or in hospital)

PAPAGENO (a pragmatic approach to the prevention of gestational diabetes and pre-eclampsia in obese pregnant women in resource poor settings)

Further information:

How to get your trial adopted and access support    
All current studies Commercial Partnerships Data Linkage Studies
Health Services Research Studies Completed Studies