DEXFEM

Developmental Clinical Studies Reversing endometrial glucocorticoid deficiency in heavy menstrual bleeding

This study builds on previous research which has provided compelling evidence that deficient activity of glucocorticoids in the endometrium is a cause of increased menstrual bleeding. This study aims to demonstrate that a glucocorticoid (dexamethasone), already in common use for other conditions, (e.g. to treat medical conditions such as asthma and rheumatoid arthritis in early pregnancy) will reverse the endometrial glucocortoid deficiency and as a result reduce menstrual blood loss.

Chief Investigator: Prof Hilary Critchley

Funder: MRC

For further information on this trial use this link: :  https://clinicaltrials.gov/show/NCT01769820)%2520(http://www.ukctg.nihr.ac.uk/trialdetails/NCT01769820)

Current status: awaiting publication

ECTU Involvement: Database and Data Management, Statistics and Randomisation Service