Edinburgh Clinical Trials


A randomised multicentre trial of a brief cognitive-behavioural intervention plus information versus information alone for the treatment of post-stroke fatigue

The purpose of this study is to assess whether a brief cognitive behavioural intervention for post-stroke fatigue leads to clinically relevant improvements in fatigue after 6 months.



Chief Investigator: Professor Gillian Mead

Number and location of participating sites / geographical scope (by region/ country): UK – 3 sites

Funder: Chest Heart & Stroke Scotland


Start and End date

Of grant award: July 2018 to October 2020

Of recruitment: ended on 31 January 2020


Current status: In analysis


Website: The POSITIF Trial


Sponsor: The University of Edinburgh and NHS Lothian – ACCORD (http://www.accord.ed.ac.uk/ ).  The Queen’s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ


Chief Investigator: Professor Gillian Mead Gillian.E.Mead@ed.ac.uk

Trial Manager: Alix Macdonald alix.macdonald@ed.ac.uk


UK GDPR Privacy Statement: If you have participated in this study and would like to read how it complies with UK GDPR, please read this document.


ECTU Involvement: Trial management, Data management, Statistics, Research Nurse