A pragmatic approach to preventing gestational diabetes and pregnancy hypertensive disorders in obese pregnant women in resource poor settings.
This is a feasibility study of a randomised clinical trial of metformin (compared with matched placebo) for the prevention of gestational diabetes and pregnancy hypertensive disorders in obese pregnant women. This study will help to determine whether we can recruit enough women to conduct a larger trial in the future, to measure if the routine administration of metformin could prevent gestational diabetes and pregnancy hypertensive disorders in obese pregnant women in resource poor settings (in Malawi and Zambia).
In this feasibility study, we will measure if women are willing to be recruited and take a medication. We will then use this information to determine, if a larger study to prevent gestational diabetes could be conducted in the future.
Chief Investigator: Jane E. Norman
Number and location of participating sites / geographical scope (by region/ country): 1 Malawi
Funder: MRC Global
Start and End date
Of grant award: 31 December 2020
Current Status: In set up
UK GDPR privacy statement: http://www.accord.ed.ac.uk/search/node/privacy
Sponsor: ACCORD http://www.accord.ed.ac.uk/
Chief Investigator: Jane E Norman - Jane.Norman@ed.ac.uk
ECTU Involvement: Statistics / Data base and randomisation service provision only