BREATHE - Health Data Research Hub for Respiratory Health


Standardised respiratory phenotypes to support research using Electronic Health Record data

BREATHE – the Health Data Research Hub for Respiratory Health, is collating a publicly available set of respiratory phenotypes for use in health research.

Available on the HDR UK CALIBER Phenotype Portal, the development of standardised phenotypes will enable researchers to draw on the wealth of information held in Electronic Health Records (EHRs).

Extracting information from Electronic Health Records (EHRs)

When a patient visits their doctor, information on their health is securely recorded in EHRs. This information is regularly updated, and can cover long periods of time, making them a valuable source of information for research.

Phenotyping algorithms are complex computer programs that extract useful information from EHRs so they can be used for health research. The development of these algorithms takes a lot of time and effort, as there are often inconsistencies and variations in how things are recorded in EHRs.

Despite the work which goes into their development, phenotyping algorithms are not often shared for others to re-use in future research. When different algorithms are used, it makes it hard to compare results.

Available on the HDR UK CALIBER Phenotype Portal

Working with Professor Spiros Denaxas, Professor of Biomedical Informatics at University College London, members of BREATHE are developing a list of phenotypes for respiratory conditions. The list is publicly available on the HDR UK CALIBER Phenotype Portal – a comprehensive, open-access resource providing the research community with information, tools and phenotyping algorithms for UK EHRs.

More phenotypes will be added over time, covering a range of respiratory conditions.

By providing a standard set of phenotypes across key respiratory conditions, BREATHE is taking steps to enable the use of Electronic Health Record data in quality health research, and ultimately deliver benefits back to UK patients.

Professor Jenni QuintBREATHE Deputy Director, and Programme Lead - Real World Evidence

Find out more

How BREATHE is supporting the use of Electronic Health Record data in research

View the respiratory phenotypes on the HDR UK CALIBER Phenotype Portal

Details about how patient data is used and kept safe is available from Understanding Patient Data