Asthma UK Centre for Applied Research


Research outputs from members of the Centre, and other relevant publications



Title Authors Reference

Real-world efficacy of treatment with benralizumab, dupilumab, mepolizumab and reslizumab for severe asthma: A systematic review and meta-analysis.

Charles D, Shanley J, Temple SN, Rattu A, Khaleva E, Roberts G.

Clin Exp Allergy. 2022 May;52(5):616-627. doi: 10.1111/cea.14112. Epub 2022 Mar 9. PMID: 35174566.

Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.

Vlieg-Boerstra B, de Jong N, Meyer R, Agostoni C, De Cosmi V, Grimshaw K, Milani GP, Muraro A, Oude Elberink H, Pali-Schöll I, Roduit C, Sasaki M, Skypala I, Sokolowska M, van Splunter M, Untersmayr E, Venter C, O'Mahony L, Nwaru BI.

Allergy. 2022 May;77(5):1373-1388. doi: 10.1111/all.15136. Epub 2021 Oct 27. PMID: 34626488.

Socioeconomic disparities in asthma health care utilization, exacerbations, and mortality: A systematic review and meta-analysis.

Redmond C, Akinoso-Imran AQ, Heaney LG, Sheikh A, Kee F, Busby J.

J Allergy Clin Immunol. 2022 May;149(5):1617-1627. doi: 10.1016/j.jaci.2021.10.007. Epub 2021 Oct 18. PMID: 34673047.

Exacerbation Profile and Risk Factors in a T2-Low Severe Asthma Population.

McDowell PJ, Busby J, Hanratty CE, Djukanovic R, Woodcock A, Walker S, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan D, Mansur AH, Fowler SJ, Diver SE, Howarth P, Lordan J, Menzies-Gow A, Harrison T, Robinson DS, Holweg CTJ, Matthews JG, Pavord ID, Heaney LG; investigators for the MRC Refractory Asthma Stratification Program.

Am J Respir Crit Care Med. 2022 May 12. doi: 10.1164/rccm.202201-0129OC. Epub ahead of print. PMID: 35549845.

Vitamin D replacement in children with acute wheeze: a dose-escalation study.

Stefanidis C, Bush A, Newby C, Nwokoro C, Liebeschuetz S, Skene IP, Griffiths CJ, Martineau AR.

ERJ Open Res. 2022 May 16;8(2):00609-2021. doi: 10.1183/23120541.00609-2021. PMID: 35586451; PMCID: PMC9108968.

Clinical Remission in Severe Asthma: A Pooled Post Hoc Analysis of the Patient Journey with Benralizumab.

Menzies-Gow A, Hoyte FL, Price DB, Cohen D, Barker P, Kreindler J, Jison M, Brooks CL, Papeleu P, Katial R.

Adv Ther. 2022 May;39(5):2065-2084. doi: 10.1007/s12325-022-02098-1. Epub 2022 Mar 14. PMID: 35287231; PMCID: PMC9056458.

Understanding Online and Offline Social Networks in Illness Management of Older Patients With Asthma and Chronic Obstructive Pulmonary Disease: Mixed Methods Study Using Quantitative Social Network Assessment and Qualitative Analysis.

Andreou A, Dhand A, Vassilev I, Griffiths C, Panzarasa P, De Simoni A.

JMIR Form Res. 2022 May 17;6(5):e35244. doi: 10.2196/35244. PMID: 35579933; PMCID: PMC9157321.

Experiences and behaviours of patients with asthma requesting prescriptions from primary care during medication shortages linked to the COVID-19-lockdown: insights from a qualitative analysis of a UK asthma online community.

Ow NL, Sadek Attalla S, Davies G, Griffiths C, De Simoni A.

BJGP Open. 2022 May 30:BJGPO.2021.0222. doi: 10.3399/BJGPO.2021.0222. Epub ahead of print. PMID: 35640963.

Breathing Exercises for Asthma Patients in Specialist Care: A Multicenter Randomized Trial.

Andreasson KH, Skou ST, Ulrik CS, Madsen H, Sidenius K, Assing KD, Porsbjerg C, Bloch-Nielsen J, Thomas M, Bodtger U.

Ann Am Thorac Soc. 2022 May 19. doi: 10.1513/AnnalsATS.202111-1228OC. Epub ahead of print. PMID: 35588357.

Electronic Inhaler Monitoring for Chronic Airway Disease: Development and Application of a Multidimensional Efficacy Framework.

Tay TR, van Boven JFM, Chan A, Hew M.

J Allergy Clin Immunol Pract. 2022 May;10(5):1189-1201.e1. doi: 10.1016/j.jaip.2021.11.027. Epub 2021 Dec 13. PMID: 34915225.

Global Variability in Administrative Approval Prescription Criteria for Biologic Therapy in Severe Asthma.

Porsbjerg CM, Menzies-Gow AN, Tran TN, Murray RB, Unni B, Audrey Ang SL, Alacqua M, Al-Ahmad M, Al-Lehebi R, Altraja A, Belevskiy AS, Björnsdóttir US, Bourdin A, Busby J, Canonica GW, Christoff GC, Cosio BG, Costello RW, FitzGerald JM, Fonseca JA, Hansen S, Heaney LG, Heffler E, Hew M, Iwanaga T, Jackson DJ, Kocks JWH, Kallieri M, Bruce Ko HK, Koh MS, Larenas-Linnemann D, Lehtimäki LA, Loukides S, Lugogo N, Maspero J, Papaioannou AI, Perez-de-Llano L, Pitrez PM, Popov TA, Rasmussen LM, Rhee CK, Sadatsafavi M, Schmid J, Siddiqui S, Taillé C, Taube C, Torres-Duque CA, Ulrik C, Upham JW, Wang E, Wechsler ME, Bulathsinhala L, Carter V, Chaudhry I, Eleangovan N, Hosseini N, Rowlands MA, Price DB, van Boven JFM.

J Allergy Clin Immunol Pract. 2022 May;10(5):1202-1216.e23. doi: 10.1016/j.jaip.2021.12.027. Epub 2022 Jan 3. PMID: 34990866.

Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma.

Khalfaoui L, Symon FA, Couillard S, Hargadon B, Chaudhuri R, Bicknell S, Mansur AH, Shrimanker R, Hinks TSC, Pavord ID, Fowler SJ, Brown V, McGarvey LP, Heaney LG, Austin CD, Howarth PH, Arron JR, Choy DF, Bradding P.

Allergy. 2022 May 17. doi: 10.1111/all.15376. Epub ahead of print. PMID: 35579040. 10.3310/HLZE0479. PMID: 35639493.

Engaging stakeholders and communities to improve respiratory health in Asia.

Jackson T, Williams S, Fernandes G.

J Glob Health. 2022 May 7;12:01001. doi: 10.7189/jogh.12.01001. PMID: 35524773; PMCID: PMC9078154.

Evaluation of sputum eosinophil count as a predictor of treatment response to mepolizumab.

Pavord ID, Buhl R, Kraft M, Prazma CM, Price RG, Howarth PH, Yancey SW.

ERJ Open Res. 2022 May 3;8(2):00560-2021. doi: 10.1183/23120541.00560-2021. PMID: 35509441; PMCID: PMC9062111.

The effects of social distancing and self-isolation during the COVID-19 pandemic on adults diagnosed with asthma: A qualitative study.

Tyson L, Hardeman W, Stratton G, Wilson AM, Semlyen J.

J Health Psychol. 2022 May;27(6):1408-1420. doi: 10.1177/13591053211012766. Epub 2021 May 4. PMID:33947267; PMCID: PMC9036148.

Sub-stratification of type-2 high airway disease for therapeutic decision-making: A 'bomb' (blood eosinophils) meets 'magnet' (FeNO) framework.

Couillard S, Pavord ID, Heaney LG, Petousi N, Hinks TSC.

Respirology. 2022 May 19. doi: 10.1111/resp.14294. Epub ahead of print. PMID: 35591794.




Publications 2020-2018

A summary of selected relevant publications by members of the Asthma UK Centre for Applied Research is available as both a PDF and an EXCEL sheet. Includes publications up to and including October 2020.