Asthma UK Centre for Applied Research


Research outputs from members of the Centre, and other relevant publications


Title Authors Reference

Temporal trends and forecasting of COVID-19 hospitalisations and deaths in Scotland using a national real-time patient-level data platform: a statistical modelling study.

Simpson CR, Robertson C, Vasileiou E, Moore E, McCowan C, Agrawal U, Stagg HR, Docherty A, Mulholland R, Murray JLK, Ritchie LD, McMenamin J, Sheikh A.

Lancet Digit Health. 2021 Aug;3(8):e517-e525. doi: 10.1016/S2589-7500(21)00105-9. Epub 2021 Jul 5. PMID: 34238721; PMCID: PMC8257056.

Digital Inhalers for Asthma or Chronic Obstructive Pulmonary Disease: A Scientific Perspective.

Chan AHY, Pleasants RA, Dhand R, Tilley SL, Schworer SA, Costello RW, Merchant R

Pulm Ther. 2021 Aug 11. doi: 10.1007/s41030-021-00167-4. Epub ahead of print. PMID: 34379316.

Effect of smoke-free policies in outdoor areas and private places on children's tobacco smoke exposure and respiratory health: a systematic review and meta-analysis.

Radó MK, Mölenberg FJM, Westenberg LEH, Sheikh A, Millett C, Burdorf A, van Lenthe FJ, Been JV.

Lancet Public Health. 2021 Aug;6(8):e566-e578. doi: 10.1016/S2468-2667(21)00097-9. Epub 2021 Jul 16. PMID: 34274050.

Risk Predictors and Symptom Features of Long COVID Within a Broad Primary Care Patient Population Including Both Tested and Untested Patients.

Jones R, Davis A, Stanley B, Julious S, Ryan D, Jackson DJ, Halpin DMG, Hickman K, Pinnock H, Quint JK, Khunti K, Heaney LG, Oliver P, Siddiqui S, Pavord I, Jones DHM, Hyland M, Ritchie L, Young P, Megaw T, Davis S, Walker S,Holgate S, Beecroft S, Kemppinen A, Appiagyei F, Roberts EJ, Preston M, Hardjojo A, Carter V, van Melle M, Price D.

Pragmat Obs Res. 2021 Aug 11;12:93-104. doi:10.2147/POR.S316186. PMID: 34408531; PMCID: PMC8366779.

The Induction of Alpha-1 Antitrypsin by Vitamin D in Human T Cells Is TGF-β Dependent: A Proposed Anti-inflammatory Role in Airway Disease.

Chen YH, Cheadle CE, Rice LV, Pfeffer PE, Dimeloe S, Gupta A, Bush A, Gooptu B, Hawrylowicz CM.

Front Nutr. 2021 Aug 12;8:667203. doi: 10.3389/fnut.2021.667203. PMID: 34458299; PMCID: PMC8397538.

Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents.

Ruffles T, Jones CJ, Palmer C, Turner S, Grigg J, Tavendale R, Hogarth F, Rauchhaus P, Pilvinyte K, Hannah R, Smith H, Littleford R, Lipworth B, Mukhopadhyay S.

Eur Respir J. 2021 Aug 19;58(2):2004107. doi: 10.1183/13993003.04107-2020. PMID: 33479111.

From DREAM to REALITI-A and beyond: Mepolizumab for the treatment of eosinophil driven diseases.

Pavord ID, Bel EH, Bourdin A, Chan R, Han JK, Keene ON, Liu MC, Martin N, Papi A, Roufosse F, Steinfeld J, Wechsler ME, Yancey SW.

Allergy. 2021 Aug 17. doi: 10.1111/all.15056. Epub ahead of print. PMID: 34402066.

Association between pre-existing respiratory disease and its treatment, and severe COVID-19: a population cohort study. Aveyard P, Gao M, Lindson N, Hartmann-Boyce J, Watkinson P, Young D, Coupland CAC, Tan PS, Clift AK, Harrison D, Gould DW, Pavord ID, Hippisley-Cox J.

Lancet Respir Med. 2021 Aug;9(8):909-923. doi: 10.1016/S2213-2600(21)00095-3. Epub 2021 Apr 1. PMID: 33812494; PMCID: PMC8016404.

Menopausal hormone therapy and women's health: An umbrella review.

Zhang GQ, Chen JL, Luo Y, Mathur MB, Anagnostis P, Nurmatov U, Talibov M, Zhang J, Hawrylowicz CM, Lumsden MA, Critchley H, Sheikh A, Lundbäck B, Lässer C, Kankaanranta H, Lee SH, Nwaru BI.

PLoS Med. 2021 Aug 2;18(8):e1003731. doi: 10.1371/journal.pmed.1003731. PMID: 34339416; PMCID: PMC8366967.

Sibship size, birth order and risk of asthma and allergy: protocol for a systematic review and meta-analysis.

Lisik D, Ioannidou A, Milani G, Nyassi S, Özuygur Ermis SS, Spolidoro GCI, Goksör E, Wennergren G, Nwaru BI.

BMJ Open. 2021 Aug 23;11(8):e045795. doi: 10.1136/bmjopen-2020-045795. PMID: 34426461.

Long-term corticosteroid use, adrenal insufficiency and the need for steroid-sparing treatment in adult severe asthma.

Gurnell M, Heaney LG, Price D, Menzies-Gow A.

J Intern Med. 2021 Aug;290(2):240-256. doi: 10.1111/joim.13273. Epub 2021 Apr 1. PMID: 33598993; PMCID: PMC8360169.

Effectiveness and perceptions of using templates in long-term condition reviews: a systematic synthesis of quantitative and qualitative studies.

Morrissey M, Shepherd E, Kinley E, McClatchey K, Pinnock H.

Br J Gen Pract. 2021 Aug 26;71(710):e652-e659. doi: 10.3399/BJGP.2020.0963. PMID: 33690148; PMCID: PMC8321439.

Does lung function change in the months after an asthma exacerbation in children?

Martin J, Pijnenburg MW, Roberts G, Pike KC, Petsky H, Chang AB, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner S.

Pediatr Allergy Immunol. 2021 Aug;32(6):1208-1216. doi: 10.1111/pai.13503. Epub 2021 Mar 29. PMID: 33721352.

The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease.

Adeloye D, Elneima O, Daines L, Poinasamy K, Quint JK, Walker S, Brightling CE, Siddiqui S, Hurst JR, Chalmers JD, Pfeffer PE, Novotny P, Drake TM, Heaney LG, Rudan I, Sheikh A, De Soyza A; International COVID-19 Airways Diseases Group.

 Lancet Respir Med. 2021 Aug 17:S2213-2600(21)00286-1. doi: 10.1016/S2213-2600(21)00286-1. Epub ahead of print. PMID: 34416191; PMCID: PMC8372501.

Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities.

Kerkhof M, Tran TN, Allehebi R, Canonica GW, Heaney LG, Hew M, Perez de Llano L, Wechsler ME, Bulathsinhala L, Carter VA, Chaudhry I, Eleangovan N, Murray RB, Price CA, Price DB.

J Allergy Clin Immunol Pract. 2021 Aug 14:S2213-2198(21)00897-7. doi: 10.1016/j.jaip.2021.07.056. Epub ahead of print. PMID: 34403837.

Biologicals in childhood severe asthma: the European PERMEABLE survey on the <i>status quo</i>.

Santos-Valente E, Buntrock-Döpke H, Abou Taam R, Arasi S, Bakirtas A, Lozano Blasco J, Bønnelykke K, Craiu M, Cutrera R, Deschildre A, Elnazir B, Fleming L, Frey U, Gappa M, Nieto García A, Skamstrup Hansen K, Hanssens L, Jahnz-Rozyk K, Jesenak M, Kerzel S, Kopp MV, Koppelman GH, Krivec U, MacLeod KA, Mäkelä M, Melén E, Mezei G, Moeller A, Moreira A, Pohunek P, Minić P, Rutjes NWP, Sammut P, Schwerk N, Szépfalusi Z, Turkalj M, Tzotcheva I, Ulmeanu A, Verhulst S, Xepapadaki P, Niggel J, Vijverberg S, Maitland-van der Zee AH, Potočnik U, Reinartz SM, van Drunen CM, Kabesch M. ERJ Open Res. 2021 Aug 16;7(3):00143-2021. doi: 10.1183/23120541.00143-2021. PMID: 34409097; PMCID: PMC8365152.

Sociocultural influences on asthma self- management in a multicultural society: A qualitative study amongst Malaysian adults.

Koh WM, Abu Bakar AI, Hussein N, Pinnock H, Liew SM, Hanafi NS, Pang YK, Ho BK, Mohamed Isa S, Sheikh A, Khoo EM.

Health Expect. 2021 Aug 27. doi: 10.1111/hex.13352. Epub ahead of print. PMID: 34449970.

Ethnic and social inequalities in COVID-19 outcomes in Scotland: protocol for early pandemic evaluation and enhanced surveillance of COVID-19 (EAVE II).

Henery P, Vasileiou E, Hainey KJ, Buchanan D, Harrison E, Leyland AH, Alexis T, Robertson C, Agrawal U, Ritchie L, Stock SJ, McCowan C, Docherty A, Kerr S, Marple J, Wood R, Moore E, Simpson CR, Sheikh A, Katikireddi SV.

BMJ Open. 2021 Aug 10;11(8):e048852. doi: 10.1136/bmjopen-2021-048852. PMID: 34376451; PMCID: PMC8359861.

Addressing a system failure to diagnose COPD and asthma.

Roberts CM, Calvert J, Hickman K, Quint JK, Sinha IP, Singh SJ, Hurst JR.

Lancet Respir Med. 2021 Aug;9(8):814-816. doi: 10.1016/S2213-2600(21)00272-1. Epub 2021 Jun 15. PMID: 34144000.

A feasibility trial of a digital mindfulness-based intervention to improve asthma-related quality of life for primary care patients with asthma.

Ainsworth B, Stanescu S, Stuart B, Russell D, Liddiard M, Djukanovic R,Thomas M

J Behav Med. 2021 Aug 27. doi: 10.1007/s10865-021-00249-3. Epub ahead of print. PMID: 34448986.

Lung health in LMICs: tackling challenges ahead.

Khoo EM, Li D, Ungan M, Jordan R, Pinnock H.

Lancet. 2021 Aug 7;398(10299):488-489. doi: 10.1016/S0140-6736(21)01230-7. PMID: 34364520.

Associations between smoke-free vehicle legislation and childhood admissions to hospital for asthma in Scotland: an interrupted time-series analysis of whole-population data.

Mackay DF, Turner SW, Semple SE, Dick S, Pell JP.

Lancet Public Health. 2021 Aug;6(8):e579-e586. doi: 10.1016/S2468-2667(21)00129-8. Epub 2021 Jul 16. PMID: 34274049.

COVID-19 vaccines: addressing hesitancy in young people with allergies.

Abrams EM, Shaker M, Sinha I, Greenhawt M

Lancet Respir Med. 2021 Aug 17:S2213-2600(21)00370-2. doi: 10.1016/S2213-2600(21)00370-2. Epub ahead of print. PMID: 34416192; PMCID: PMC8372552.

Derivation of a prototype asthma attack risk scale centred on blood eosinophils and exhaled nitric oxide.

Couillard S, Laugerud A, Jabeen M, Ramakrishnan S, Melhorn J, Hinks T, Pavord I.

Thorax. 2021 Aug 6:thoraxjnl-2021-217325. doi: 10.1136/thoraxjnl-2021-217325. Epub ahead of print. PMID: 34362839.

Aeroallergen sensitization for detecting asthma in primary care: A diagnostic test accuracy study.

Kocks JWH, Andringa HJH, van Heijst E, Louis R, Ojanguren Arranz I, Riemersma RA, Ryan D, Usmani OS, Flokstra-de Blok BMJ.

Clin Exp Allergy. 2021 Aug;51(8):1080-1084. doi: 10.1111/cea.13888. Epub2021 May 11. PMID: 33914988.

Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST.

Maspero JF, FitzGerald JM, Pavord ID, Rice MS, Maroni J, Rowe PJ, Pirozzi G, Amin N, Ruddy M, Graham NMH, Teper A, Hardin M. ​​​​​​

Allergy. 2021 Aug;76(8):2621-2624. doi: 10.1111/all.14872. Epub 2021 May 10. PMID: 33905544; PMCID: PMC8360078.

Predicted COVID-19 positive cases, hospitalisations, and deaths associated with the Delta variant of concern, June- July, 2021.

Shah SA, Moore E, Robertson C, McMenamin J, Katikireddi SV, Simpson CR, Shi T, Agrawal U, McCowan C, Stock S, Ritchie LD, Sheikh A; Public Health Scotland and the EAVE II Collaborators.

Lancet Digit Health. 2021 Sep;3(9):e539-e541. doi: 10.1016/S2589-7500(21)00175-8. Epub 2021 Aug 9. PMID: 34384736; PMCID: PMC8352493.



Publications 2020-2018

A summary of selected relevant publications by members of the Asthma UK Centre for Applied Research is available as both a PDF and an EXCEL sheet. Includes publications up to and including October 2020.