Asthma UK Centre for Applied Research

Adam Peel

Project: The utility of biomarkers in the management of acute asthma: a feasibility study

PhD overview

PhD Title: The utility of biomarkers in the management of acute asthma: a feasibility study

Funded by: Asthma UK

Supervisors: Professor Andrew Wilson, Professor Yoon Loke, Dr Gwyneth Davies, Dr Stephen Fowler

Based at: University of East Anglia


Headshot of Adam Peel
Asthma UK Centre for Applied Research PhD student Adam Peel

Existing ways of assessing asthma (such as peak flow meters) tell us about lung function and how well people are breathing but they don’t actually tell us how inflamed their airways are nor what the most appropriate treatment is. Every time a person exhales, they breathe out water vapour and various gases; dissolved in the water vapour are different substances that come from the lining of the airways. We hope that by capturing and examining these compounds during an asthma attack we can discover which ones provide the most reliable and useful information for guiding treatment and managing patients. There is a growing body of research in this field; this PhD study aims to determine the feasibility of such a study in the acute hospital setting.

About me

My research interests lie in the management of chronic disease; from issues around therapy adherence to the use of technology to guide treatment and management. My current focus is on breathomics – the analysis of volatile organic compounds in exhaled breath – for biomarker discovery, diagnosis and disease management. I hold undergraduate degrees in Social Sciences, Osteopathy and Nursing, and am a registered nurse practicing at the Norfolk & Norwich University Hospital.


Research activity (conferences, congress, annual scientific meeting)

  • Terrington, D. Hayton, C. Fowler, S. Wilson, A. (2018) Exhaled Breath Biomarkers in Sarcoidosis: A Systematic Review. European Respiratory Society Conference (poster presentation).
  • Peel, A. (2017) Joint Centre meeting with the MRC & Asthma UK Centre in Allergic Mechanisms of Asthma - a PhD perspective. Weblog; Asthma UK Centre for Applied
  • Peel, AM. Fowler, SJ. Davies, GA. Wilson, AM. Loke, YK (2017) Asthma Bronchial Challenge: A Study in Breathomics. Poster presentation. AUKCAR MRC Asthma UK Joint Centre Event 20/09/2017 & AUKCAR Annual Scientific Meeting 23/01/2018
  • Peel, AM. Crossman-Barnes, CJ. Tang, J. Fowler, SJ. Davies, GA. Wilson, AM. Loke, YK (2016) Biomarkers in Adult Asthma: A Systematic Review of 8-Isoprostane in Exhaled Breath Condensate. British Thoracic Society Winter Meeting, Oral Presentation. 7/12/2016
  • Peel, AM. Crossman-Barnes, CJ. Tang, J. Fowler, SJ. Davies, GA. Wilson, AM. Loke, YK (2016) 8-isoprostane in Exhaled Breath Condensate: A Systematic Review in Adult Asthma. Asthma UK Annual Scientific Meeting, Oral Presentation. 9/11/2016
  • Christina-Jane Crossman-Barnes, Adam Peel, Rebekah Fong-Soe-Khioe, Tracey Sach, Andrew Wilson, Garry Barton (2016) Economic evidence for non-pharmacological asthma management interventions: Systematic Review. Asthma UK Annual Scientific Meeting, Poster Presentation. 9/11/2016
  • Peel, A. Fowler, S. Davies, G. Loke Y. Wilson, A. (2016) Biomarkers in the Management of Acute Asthma: A Feasibility Study. UEA Faculty of Medicine & Health Sciences Student Conference, Poster Presentation. 03/03/2016 


Funded by Asthma UK