Dr Ian Morrison

Dr Morrison is a Consultant Neurologist at Ninewells Hospital, Tayside and a Consultant in Sleep Medicine at the Royal Infirmary of Edinburgh.

Background

Dr Morrison has a specialist clinical interest in the diagnosis and management of patients with complex sleep behaviour disorders and epilepsy, and he is the author of a number of articles on these subjects.

He is the Chair of the Tayside and West of Scotland Managed Clinical Network for epilepsy.

Dr Morrison graduated from the University of Glasgow, completing his clinical training in the Institute of Neurological Sciences in Glasgow, and has been in post in Tayside since 2011, and Lothian since 2013.

He completed his PhD in Neurosciences with Professor Hugh Willison at the University of Glasgow, and Professor Wes Thompson at the University of Texas in Austin, studying the pathogenesis of autoimmune neuropathies.

He previously worked with Professor Jack Griffin in Johns Hopkins hospital, Baltimore and has received funding support from the Wellcome Trust, Patrick Berthoud Trust and Carnegie Trust.

Research interests

Dr Morrison's main research interests include understanding the pathogenesis of both rapid eye movement and non-rapid eye movement sleep disorders and the forensic implications of sleep behaviours. He is also involved in the running of trials for new epilepsy treatments.

Selected bibliography

Sleep medicine

Selby KE, Morrison I, Riha RL. Psychiatric co-morbidity in Arousal Disorders: Chicken or egg. Journal of Neuropsychology and Clinical Neurosciences 2012;24:E36-E36

Morrison I, Riha RL, Douglas NJ, Horne JA. Dangers of driving after night-shifts. British Medical Journal (Careers) 2012. Vol 344, Issue 7855

White C, Hill EA, Morrison I, Riha RL. Diagnostic delay in REM behaviour disorder. Journal of Clinical Sleep Medicine 2012, Vol8, No22

Morrison I, Riha RL. Excessive daytime sleepiness and narcolepsy - an approach to investigation and management. European Journal of Internal Medicine 2012. Vol 23(2), pp 110-117

Morrison I, Bušková J, Nevšimalová S, Douglas N, Riha RL. Diagnosing narcolepsy with cataplexy on history alone: challenging the International Classification of Sleep Disorders (ICSD) criteria. European Journal of Neurology 2011 Jul;18(7):1017-20

Morrison I, Frangulyan R, Riha RL. Beta-blockers as a cause of violent REM sleep behaviour disorder. American Journal of Medicine. 2011 Jan;124 (1):e11

Autoimmune neuropathies

Rupp A, Morrison I, Halstead SK, Townson KH, Greenshields KN, Willison HJ. Motor nerve terminal destruction and recovery following anti-ganglioside and complement mediated injury: an in-vivo and ex-vivo experimental imaging study in the mouse. Experimental Neurology 2012 Feb;233(2):836-48

Gabreyes A, Abbasi H, Forbes KP, McQuaker G, Duncan A, Morrison I. Hypocupremia Associated Cytopenia and Myelopathy: A National Retrospective Review. European Journal of Haematology. 2013 Jan;90(1):1-9

Morrison I, Li Y., Halstead SK, Thompson WJ, Willison HJ. The consequences of terminal Schwann cell ablation at the murine neuromuscular junction observed through in vivo imaging Journal of the Peripheral Nervous System 2007

Morrison I, Halstead SK, O'Hanlon GM, Humphreys PD, Goodfellow JA, Plomp JJ, Willison JH. An anti-disialosyl antibody causing perisynaptic Schwann cell death at mouse neuromuscular junctions. Journal of the Peripheral Nervous System 2005

Halstead SK, Morrison I, O'Hanlon GM, Humphreys PD, Goodfellow JA, Plomp JJ, Willison HJ. Anti-disialosyl antibodies mediate selective neuronal or Schwann cell injury at mouse neuromuscular junctions. Glia (2005) Vol. 52 (pp177-189)

O'Hanlon GM, Plomp JJ, Chakrabarti M, Morrison I, Wagner ER, Goodyear CS, Yin X, Trapp BDT, Conner J, Molenaar PC, Stewart S, Rowan EG, Willison HJ. Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain (2001). Vol. 124(5)(pp 893-906)

Goodyear CS, O'Hanlon GM, Plomp JJ, Wagner ER, Morrison I, Veitch J, Cochrane L, Bullens RW, Molenaar PC, Conner J, Willison HJ. Monoclonal antibodies raised against Guillain-Barre syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations. Journal of Clinical Investigation (1999) Vol. 104 (pp 697-708)

Goodyear CS, O’Hanlon GM, Morrison I, Willison HJ. Characterisation of anti-ganglioside antibodies cloned from mice immunised with Miller-Fisher Syndrome associated strains of Campylobacter jejuni lipopolysaccharide. Muscle and Nerve (1998), Supplement 7 S11 No 4

Epilepsy and general neurology

Morrison I, Razvi SSM. Driving regulations and psychogenic non-epileptic seizures: Perspectives from the United Kingdom. Seizure: European Journal of Epilepsy 2011, pp. 177-180

Morrison I, Razvi SSM, Metcalfe RA, Duncan R. External and internal ophthalmoplegia, facial diplegia, ataxia and exaggerated deep tendon reflexes associated with anti-GQ1b antibodies: a new variant of acute ophthalmoparesis. Scottish Medical Journal (2010) Vol. 55(1)

Reid JM, Morrison I, Gorrie G, Metcalfe RA. Positive “ice on eyes” test in Miller Fisher syndrome. Practical Neurology 2008, 000: 1-2

Morrison I, McEntagart A, Capell H. Polymyositis with cardiac manifestations and unexpected immunology. Annals of the Rheumatic Disease (2002). Vol. 61(12) (pp 1110-1111)