Mr. O’Neill graduated from Edinburgh Medical School with Honours in 2005 and joined the South-East Scotland surgical training programme in 2007. He was appointed to the ECAT training programme in 2009 and completed his PhD in the Edinburgh Cancer Research Centre in 2013 under the supervision of Professor Ted Hupp and Professor Rebecca Fitzgerald.
Oesophageal cancer is the four leading cause of cancer death in Scotland. Oesophageal adenocarcinoma (OAC), the predominant subtype, is largely resistant to current chemotherapies and the majority of patients succumb to systemic disease. My research aims to identify novel therapeutic targets for this disease. I have established an oesophageal tissue resource and am using proteomic methods to identify cancer-specific proteins and computational and network analysis methods to understand OAC biology. I lead the Edinburgh component of the OCCAMS multicentre collaborative; currently undertaking the oesophageal adenocarcinoma genome project.
I have both wet-lab, computational and clinical research studies in progress and welcome motivated students to get in touch by email if you are interested in joining this work.
Funding and Support
PhD funded by the Wellcome Trust, as part of the ECAT programme.
- Bachelor of Science (Bsc Hons First Class), Physiology, 2002. University of Edinburgh
- Bachelor of Medicine and Bachelor of Surgery (MB ChB with Honours) 2005. University of Edinburgh
- Member Royal College of Surgeons of Edinburgh (MRCSEd) 2008. Royal College of Surgeons of Edinburgh
- Doctor of Philosophy 2014