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Postdoctoral Research Fellow

To functionally map the impact of cattle genetic variants on gene regulation and disease. Closing on 25 Oct.

Fixed Term: 30 months, Grade 7 (£34,304 - £40,927)

The mammalian and host-pathogen genomics groups at the Roslin Institute are looking for a research fellow to join our inter-disciplinary team to use state-of-the-art gene editing and functional genomics approaches to functionally map the impact of cattle genetic variants on gene regulation and disease. The fellow will use the genome-wide massively parallel reporter assay (MPRA), CRISPR/Cas9, and single-cell screening approaches to characterise the variants driving important cattle phenotypes and investigate their mode of action. The researcher will benefit from being part of a wider inter-disciplinary group of wet- and dry-lab researchers working on both human and livestock genomics. With the Roslin institute being one of the world’s leading livestock research institutes and a member of the Centre for Tropical Livestock Research Institute, the applicant will have access to a range of resources, training opportunities and core expertise.

The position will be on grade 7 (salary above) and is available initially for 30 months. Informal enquiries can be directed to Dr Musa Hassan (Musa.Hassan@roslin.ed.ac.uk) and Dr James Prendergast (james.prendergast@roslin.ed.ac.uk).

Please apply with your CV and a cover letter outlining your suitability for the role addressing the criteria set out in the skills section.

Your skills and attributes for success:

Essential skills:

  • A PhD in a relevant discipline in molecular biology, genetics, cell biology, biochemistry, or similar.
  • Previous work experience in a laboratory and superior skills in basic molecular biological methods such as cloning, sterile cell culture, and PCR.
  • Knowledge and experience with RNA/DNA modification methods, preferably with some working experience with CRISPR/Cas9.
  • Ability to quickly learn and independently apply new techniques after initial training
  • Exceptional organizational and time management skills and computer literacy for the recording and communication of results.

Desired skills:

  • Experience with relevant high-throughput molecular assays
  • Prior experience with lentivirus production, and transduction or transfection of mammalian cells.
  • Ability to communicate clearly and concisely with a variety of scientists at all levels.
  • Demonstrated ability to adapt to changing priorities and workloads.

Futher Information

All applicants are encouraged to apply online. The application process is quick and easy to follow, and you will receive email confirmation of safe receipt of your application. Applications should be received by the closing date of 25 October 2021.

Further information and application