Ruminant functional genomics

The Ovine FAANG Project

We are creating an atlas of transcription starts sites for the new sheep genome

Ovine FAANG Project Logo
The Ovine FAANG Project

The Ovine FAANG Project is a collaborative effort by the International Sheep Genomics Consortium to provide a comprehensive annotation of the new highly contiguous reference genome for sheep Oar_rambouillet_v1.0.

The project has three objectives:

  1.  to develop a deep and robust dataset of transcribed elements and regulatory features in the sheep genome;
  2.  to provide a high-quality annotation of the new ovine reference assembly;
  3.  to provide ovine FAANG data and support to the livestock genomics community.

To contribute to these objectives we have generated a high-resolution atlas of transcription start sites (TSS) for sheep, using Cap Analysis Gene Expression (CAGE) sequencing of tissue samples collected from the reference ewe Benz2616.

Mapping of TSS is a key first step in understanding transcript regulation and diversity. When complete the ovine Funcation Annotation of Animal Genomes (FAANG) project will provide one of the highest resolution annotations of a livestock species to date.

The Ovine FAANG project is led by the University of Idaho and is supported by the National Institute of Food and Agriculture, U.S. Department of Agriculture, award number USDA-NIFA-2017-67016-26301.

Related Links

Funded FAANG projects

Functional Annotation of Animal Genomes (FAANG)

The FAANG data portal

International Sheep Genomics Consortium