Understanding Development and Disease
|Name (sorted in ascending order)||Role||Research Interests|
|Prof David Argyle||William Dick Chair of Veterinary Clinical Studies||
Mechanistic studies into canine disease, specifically the focus of my research is comparative cancer biology. This involves studies on the stem cell basis of cancer through to the translation of new therapeutics into clinical development.
|Dr Adam Balic||Roslin Research Fellow||
Defining the molecular and cellular mechanisms that underpin lymphoid organ development in chickens. Developing and exploiting novel gene transfer and editing technologies in order to visualise and manipulate specific chicken immune cell populations.
|Dr Tom Burdon||Group Leader/Senior Research Fellow||
Regulation of growth and differentiation of embryo derived stem cells.
|Dr David Collie||Group Leader/Reader||
Pathophysiologic mechanisms underlying lung disease.
|Dr Xavier Donadeu||Reader||
I lead a research group working in the areas of Stem Cell biology and Reproductive Biology in large animal species. We are interested in these species both from a veterinary perspective and as disease models. Work in my laboratory spans from hypothesis-led studies to understand basic cell, organ and whole animal biology and physiology, all the way through to translational studies with industry to develop novel molecular diagnostics and cell-based therapies to address specific key challenges faced by the livestock (cattle) industry and companion animal sectors. My laboratory is best known for pioneering work on 1) the use of miRNAs as novel diagnostic biomarkers for cattle, and 2) the generation and application of stem cells, particularly induced pluripotent stem cells (iPSCs), in farm species (horse, cattle, pigs).
|Prof Colin Farquharson||Personal Chair of Skeletal Biology||
Identification of the cellular and molecular mechanisms responsible for bone and cartilage growth, development and mineralisation in health and disease.
|Dr Denis Headon||Group Leader/Senior Research Fellow||
Development, maintenance and repair of the skin and its appendages.
|Professor Ian Jackson||Programme Leader/ Professorial Fellow||
Mouse models of human and animal disease
|Dr Vicky MacRae||Reader||
Investigating new mechanisms of bone formation and vascular calcification.
|Dr Gerry McLachlan||Group Leader/Senior Research Fellow||
Preclinical studies to evaluate safety and efficacy of vectors for respiratory gene/miRNA delivery in mice & sheep. Sheep as a large animal model for respiratory disease.
|Professor Simone Meddle||Personal Chair of Behavioural Neuroendocrinology||
Adaptations of the neuroendocrine system: hormonal and neural regulation of reproduction and behaviour. Animal Welfare: Neurobiology of positive welfare and behaviour.
|Dr Joe Rainger||Roslin Research Fellow|
|Professor Bruce Whitelaw||Genus Personal Chair of Animal Biotechnology||
Development of genetically engineered livestock for biomedical and agricultural applications.
Career Track fellow
|Name (sorted in descending order)||Role||Research Interests|
|Dr Douglas Vernimmen||Chancellors Fellow/Research Fellow||
Our collaborative research with Prof K Kranc is to address the precise functions of epigenetic regulators in myeloid leukaemia using in vitro, ex-vivo and in vivo models. Together with additional screening in patients for mutations in this gene, this research will enable us to develop new approaches to treat leukaemia.