Infection and Immunity
Head of Department
Group Leaders/Career Track Fellows
|Name (sorted in ascending order)||Role||Research Interests|
|Pip Beard||Senior Lecturer and Principal Investigator||
The aim of my research is to understand the interactions between large DNA viruses and their host, and translate this knowledge into clinical outcomes. My research team focuses on the three capripoxvirus species (lumpy skin disease virus, sheeppox virus and goatpox virus) which each cause severe disease in livestock in Africa, Asia and the Middle East.
In addition to my research I am the OIE laboratory expert for capripoxviruses at the Pirbright Institute and provide advice to international agencies on the control of these viruses. I lead the European Commission funded project DEFEND which is tackling the emergence of African swine fever and lumpy skin disease in Europe in partnership with 31 other consortium members including industry partners ID-VET and Zoetis. (EU H2020 research programme 773701).
|Professor Mark Bronsvoort||Personal Chair of Veterinary Epidemiology||
I currently have a broad portfolio of interests including the epidemiology of foot-and-mouth disease and bovine tuberculosis and using molecular tools to understand transmission and spread at different scales in LMICs.
|Dr Tim Connelley||Roslin Research Fellow|
|Dr Abigail Diack||Roslin Research Fellow||
Human and animal prion disease pathogenesis and strain characterisation.
|Professor Ross Fitzgerald||Personal Chair of Molecular Bacteriology||
Use of genomic and molecular tools to examine the evolution and pathogenesis of clinically important species of Staphylococci and Legionella
|Professor David Gally||Personal Chair of Microbial Genetics||
My research aims to define the genetic determinants that contribute to the spread of important zoonotic diseases such as those caused by enterohaemorrhagic E. coli and Salmonella. Current work is applying machine learning and phylogenomics to predict the source and disease threat of isolates. The other main focus of our research is to understand the expression of bacterial colonisation factors and apply this knowledge to develop vaccines to limit bacterial zoonotic diseases.
|Eleanor Gaunt||Sir Henry Dale Fellow|
|Dr Finn Grey||Senior Research Fellow||
Identifying host pathogen interactions using systems approaches
|Dr Musa Hassan||Chancellor's Fellow|
|Professor Jayne Hope||Personal Chair of Immunology||
Immune responses to Mycobacterial infections in cattle.
|Dr Fiona Houston||Senior Research Fellow/Group Leader||
Molecular mechanisms underlying the pathogenesis of infectious and neurological diseases of ruminant livestock.
|Dr Deborah Hoyle||Career Track Fellow/Research Fellow||
Molecular epidemiology of zoonotic and emerging pathogens, surveillance and disease control.
|Dr Samantha Lycett||Senior Lecturer / Group Leader - Pathogen Phylodynamics||
Pathogen Phylodynamics - evolution and epidemiology of viruses and bacteria using bayesian and machine learning methods.
|Nicola Lynskey||Career Track Fellows||
The overall interest of the Lynskey Lab is the study of virulence factor regulation and innate immune modulation by pathogenic streptococci. Our work is currently focused on two important pathogens, Streptococcus agalactiae (group B Streptococcus), the causative agent of economically important infections in multiple animal hosts which has also emerged as a major human pathogen, and the human pathogen Streptococcus pyogenes (group A Streptococcus). We seek to identify regulatory genes that enable the bacteria to switch from a benign to invasive disease state and characterise their mechanism of action and impact on host immune defences. We are also interested to use this information to better understand and characterise the factors driving host-species adaptation of S. agalactiae, which causes significant disease in humans, cattle and fish.
|Professor Neil Mabbott||Personal Chair of Immunopathology||
Host-pathogen interactions in the mucosal immune system.
|Professor Ivan Morrison||Professor Ivan Morrison||
The mechanisms of T cell-mediated immunity against intracellular pathogens of ruminants and how dysregulation of such responses can result in enhanced pathology.
|Dr Liam Morrison||Senior Research Fellow||
I am interested in the infection biology of protozoan parasites of livestock. I am particularly attracted to integrated approaches where we can learn about both host and parasite processes that are key to infection/disease progression – especially in the clinically relevant host, the cow. I work primarily on African trypanosomes, but also on Theileria parva , which together are the most significant pathogens affecting livestock in sub-Saharan Africa. I also work on Cryptosporidium parvum, a worldwide enteric pathogen of humans and livestock. My work aims to identify key host-parasite interactions that determine disease outcome, further our understanding of bovine immunobiology, and identify targets for interventions (e.g. drug & vaccine development).
|Professor Tanja Opriessnig||Chair of Infectious Disease Pathology, Group Leader||
Infectious disease models; Intervention strategies; Pathology; Veterinary diagnostics; Pigs.
|Dr Jo Stevens||Group Leader||
Studies intracellular bacterial pathogens, with specific interest in the bacterial genes required for intracellular survival and evasion of innate immune responses.
|Professor Mark Stevens||Personal Chair of Microbial Pathogenesis||
Salmonella, Campylobacter and Escherichia coli infections in farm animals, with emphasis on the bacterial and host factors that influence persistence, pathogenesis and protection.
|Professor Lonneke Vervelde||Personal Chair of Veterinary Immunology &Infectious Diseases||
Host-pathogen interactions and immunomodulation in avian species.
In vitro/ex vivo organ cultures - organoids.
Clinical Research Associates
|Name (sorted in descending order)||Role||Research Interests|
|Dr Neil Anderson||Lecturer||
My research interests are currently focussed on the epidemiology and ecology of trypanosomiasis in sub-Saharan Africa and the health of wild raptor populations in Scotland.
|Dr Alexander Corbishley||Senior Lecturer in Farm Animal Practice||
|Dr Jorge Del-Pozo||Senior Lecturer in Veterinary Anatomic Pathology||
My main research interest is to improve the understanding of infectious fish disease pathogenesis and resistance, and research in pathology morphometric approaches. I also provide pathology input on a range of collaborative research projects (e.g. squirrel leprosy, canine mast cell tumour metastasis, pulmonary hypertension models, radiation induced lung injury models, and surgical approaches to canine liver biopsy sampling).
|Dr Deborah Gow||Senior Lecturer in Veterinary Dermatology, EBVS® European Specialist & RCVS Specialist in Veterinary Dermatology|
|Prof Danielle Gunn-Moore||Personal Chair of Feline Medicine||
As a RCVS recognised Specialist in Feline Medicine, I am interested in all aspects of feline internal medicine, though I have current projects on Mycobacterial infections, feline genomics and dementia.
|Prof Anna Meredith||Personal Chair of Zoological and Conservation Medicine||
Red squirrel surveillance and infectious diseases (squirrelpox, squirrel leprosy); Scottish wildcat conservation and infectious diseases; a novel Amphibiocystidium disease in palmate newts on the Isle of Rum; Scottish raptor mortality; infectious diseases of pine martens
|Dr Tim Nuttall||Senior Lecturer in Veterinary Dermatology||
The genetics of atopic dermatitis; allergen specific immunology; antibiotic resistance, particularly meticillin-resistance staphylococci and multi-drug resistant E. coli; and responsible antimicrobial use and infection control.
|Mr Maciej Parys||Vet Clinical Lectureship||
My current research interests include studying the role of immune checkpoints in canine and feline cancer and inflammatory disease. I am also intereted in interactions between innate and adaptive immune system in cancer patients.
|Dr Gavin Paterson||Senior Lecturer in Molecular and Applied Microbiology|
|Prof Scott Pirie||Personal Chair of Equine Clinical Sciences||
Aetiopathogenesis of equine airway disease and characterising the equine pulmonary innate immune response. Equine dysautonomia, primarily in relation to the investigation of aetiologic pathways.
Scotts currently active areas of reseach include the following:
(1) studies on equine grass sickness with a particular focus on the potential aetiological role of ingested pasture-derived mycotoxins;
(2) studies of the innate immunity of the equine airway, with a particular focus on the role of the alveolar macrophage in determining disease susceptibility;
(3) studies on the role of intestinal macrophage activation in the initiation and maintenance of gut motility disturbances following gastrointestinal surgery (post-operative ileus).
|Dr Patrick Pollock||Senior Lecturer in Equine Surgery||
Wound healing in horses and other species. Poor perforance in horses. The structure and function of the equine airway. Acute phase proteins.
|Prof Neil Sargison||Personal Chair of Farm Animal Practice||
Use of deep amplicon sequencing approaches to study nematode parasite diversity and co-infections. Performance of different sheep breeds and selected lines in a harsh hill environment. Changing epidemiology of trematode parasites. Population genetics of anthelmintic resistance in nematodes. Haemonchus contotus and Teladorsagia circumcincta genomics. Train-the-trainer livestock health education.
|Dr Tobias Schwarz||Reader in Diagnostic Imaging DI Service Head||
Veterinary diagnostic imaging, in particular computed tomography
|Mr Alessandro Seguino||Senior Lecturer||
Current research interests are mainly in the wild game sector, in particular looking at Campylobacter colonisation of pheasants and E, coli STEC in venison and their relevance to public health. I am also interested in innovative ways of teaching veterinary public health.
|Dr Darren Shaw||Reader in Comparative Epidemiology||
Comparative epidemiology of parasitic and infectious diseases and general aspects of animal health.
|Name (sorted in ascending order)||Role||Research Interests|
|Sander Granneman||MRC Senior Non-Clinical Research Fellow in RNA Biochemistry and Group Leader||
My lab is interested in the role of RNA regulators and RNA binding proteins in the regulation of gene expression. Most of our research has focussed on the assembly of large macromolecular complexes, such as the yeast ribosome. However, more recently, we have also been working on understanding the role of RNA surveillance factors in the regulation of mRNA transcription and translation in both yeast and pathogenic bacteria. The goal of our research is to obtain detailed mechanistic insights into the strategies that organisms use for regulating gene expression during rapid adaptive responses. For our research we use highly innovative methodologies such as CRAC and CLASH and high-throughput structure probing methods. Our work is funded by the BBSRC, SULSA, the Wellcome Trust and the Medical Research Council.
|Dr Takanori Kitamura||Chancellor's Fellow||
Solid tumours include a range of immune cells that promote tumour development such as regulatory T (Treg) cell, myeloid derived suppressor cell (MDSC), tumour-associated macrophage (TAM), and neutrophil (TAN). I am interested in their roles in metastatic tumour outgrowth and effects on anti-tumour immune reactions as well as efficacy of immunotherapy.