The Roslin Institute
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Functional Genetics and Development

Staff list

Head of Department:

Professor Helen Sang

Personal Chair of Vertebrate Molecular Development

Contact details

Research Interests:
Applications of transgenesis in the chick, particularly in study of the development of the chick embryo and resistance to disease.

Group Leaders / Career Track Fellows

Name (sorted in ascending order) Role Research Interests
Prof David Argyle William Dick Chair of Veterinary Clinical Studies

Mechanistic studies into canine disease, specifically the focus of my research is comparative cancer biology.  This involves studies on the stem cell basis of cancer through to the translation of new therapeutics into clinical development.

Dr Kenneth Baillie Snr. Clinical Research Fellow in Anaesthesia & Critical Care

Translational genomics in critical care medicine.

Dr Adam Balic Roslin Research Fellow

Defining the molecular and cellular mechanisms that underpin lymphoid organ development in chickens. Developing and exploiting novel gene transfer and editing technologies in order to visualise and manipulate specific chicken immune cell populations.

Dr Tom Burdon Group Leader/Senior Research Fellow

Regulation of growth and differentiation of embryo derived stem cells.

Dr Mike Clinton Group Leader/Senior Research Fellow

Molecular control of sex determination and gonadal development. Mechanisms underlying sexual dimorphisms in birds. Micro-RNA regulation of cell and tissue differentiation.

Dr David Collie Group Leader/Reader

Pathophysiologic mechanisms underlying lung disease.

Dr Megan Davey Group Leader

Our current projects include:

  • The embryological origin of radial aplasia
  • Fate mapping the limb bud and the control of co-ordinated development of limb anatomy
  • Developing novel avian transgenic tools for developmental biology
  • The evolution of limb pattern in birds
  • The function of TALPID3
Dr Xavier Donadeu Reader

My research interests lie in the areas of Stem Cell biology and Reproductive Biology in large animal species. I am interested in these species both from a veterinary perspective and as disease models.  

Prof Colin Farquharson Personal Chair of Skeletal Biology

Identification of the cellular and molecular mechanisms responsible for bone and cartilage growth, development and mineralisation in health and disease.

Dr Denis Headon Group Leader/Senior Research Fellow

Development, maintenance and repair of the skin and its appendages.

Professor Ian Jackson Programme Leader/ Professorial Fellow

Mouse models of human and animal disease

Dr Vicky MacRae Reader

Investigating new mechanisms of bone formation and vascular calcification.

Dr Mike McGrew Senior Lecturer

Biobanking and gene editing of avian germ cells

 

Dr Gerry McLachlan Group Leader/Senior Research Fellow

Preclinical studies to evaluate safety and efficacy of vectors for respiratory gene/miRNA delivery in mice & sheep. Sheep as a large animal model for respiratory disease.

Professor Simone Meddle Personal Chair of Behavioural Neuroendocrinology

Adaptations of the neuroendocrine system: hormonal and neural regulation of reproduction and behaviour.  Animal Welfare: Neurobiology of positive welfare and behaviour.

Dr Joe Rainger Roslin Research Fellow
Dr Douglas Vernimmen Chancellors Fellow/Research Fellow

Our collaborative research with Prof K Kranc is to address the precise functions of epigenetic regulators in myeloid leukaemia using in vitro, ex-vivo and in vivo models. Together with additional screening in patients for mutations in this gene, this research will enable us to develop new approaches to treat leukaemia.

Professor Bruce Whitelaw Genus Personal Chair of Animal Biotechnology

Development of genetically engineered livestock for biomedical and agricultural applications.

Dr Thomas Wishart Group Leader

Elucidating the mechanisms underpinning neuronal development, stability and degeneration in health and disease.

Clinical Research Associates

Name (sorted in ascending order) Role Research Interests
Dr Sally Argyle Senior Lecturer
Dr Guraa Bergkvist Senior Lecturer

My research interests are in molecular pathways that become dysregulated in cancer and dysregulation of osteoclasts in bone. 

Prof Brendan Corcoran Personal Chair of Veterinary Cardiopulmonary Medicine

Mitral valve disease in dogs, tissue engineered solutions to sourcing valve tissue for research.

Prof Padraic Dixon Personal Chair of Equine Surgery

Aetiopathogenesis of equine dental and upper airway disorders.

Dr Adam Gow Senior Lecturer in Small Animal Medicine

In vitro production of functional canine hepatocytes from stem cell sources.

Canine liver disease and pathogenesis of hepatic encephalopathy. 

Dr John Keen Senior Lecturer

The equine cardiovascular system and its relationship to endocrinological disorders such as equine metabolic syndrome and pituitary pars intermedia dysfunction.

Mrs Yolanda Martinez-Pereira Senior Lecturer in Cardiopulmonary Medicine

Clinical biomarkers of congestive heart failure in canine patients Novel diagnostic tools in canine mesothelioma

Prof Bruce McGorum Personal Chair of Equine Medicine

Equine internal medical disorders, particularly equine respiratory diseases and grass sickness.

Dr Sarah Taylor Senior Lecture in Equine Orthopeadics

Advanced imaging of equine fractures

miRNAs and osteoarthritis

miRNAs and SNPs in equine stress fractures

 

Dr Erin Williams Senior Lecturer in Applied Veterinary Anatomy

Associate Scientists

Name (sorted in ascending order) Role Research Interests
Dr Thalia Blacking Lecturer in Applied Vet Physiology
Prof Eddie Clutton Personal Chair of Veterinary Anaesthesiology
Dr Joe Rainger Roslin Research Fellow

Sub-divisions