How to make better vaccines for humans and animals
Jayne Hope, a Roslin Institute scientist, reports on a project she led, which discovered why some vaccines are not as effective at stimulating an immune response as we would hope.
Researchers at the Institute for Animal Health (IAH) and collaborators at the Jenner Institute, University of Oxford, have discovered why some vaccines are not as effective at stimulating an immune response as we would hope and have investigated ways in which improvements could be made.
Dr Jayne Hope led the work at IAH in Compton, Berkshire prior to her recent move to The Roslin Institute, University of Edinburgh. The research was a collaboration with Dr Efrain Guzman and Dr Bryan Charleston at IAH and Professor Sarah Gilbert at Jenner Institute. The work, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) is published this week in the journal, Vaccine. For more information about the project, visit Dr Hope's research pages or the Institute for Animal Health website.
This research is published in Vaccine in the article entitled Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin.
doi 10.1016/j.vaccine.2012.01.036 and copyright is (c) 2012 Elsevier Ltd. All rights reserved.