National Avian Research Facility
National Avian Research Facility

Inbred white Leghorn lines SPF

White Leghorn inbred lines have been extensively used for many years to investigate the genetic basis of disease resistance and susceptibility (1-3). MHC haplotypes and known resistance and susceptibility are detailed below*.

*The MHC haplotypes and differential resistance and susceptibilities of the lines to pathogens itemised below have not been validated in recent years.

These lines are available from the SPF unit.


Currently, we have a good egg supply between March-September, a limited supply in September-November and in February.

Eggs are not available from November to January.

For the inbred lines advanced notice is required for large numbers of eggs or chicks, or if eggs or chicks are required outwith March to September.  Contact the NARF directly with requests (


  1. Bacon, L. D., H. D. Hunt, and H. H. Cheng. 2000. A review of the development of chicken lines to resolve genes determining resistance to diseases. Poult. Sci. 79:1082-1093.
  2. Stone, H.A. 1975. Use of highly inbred chickens in research. USDA-ARS Technical Bulletin No. 1514, Washington, DC.
  3. Waters, N. F. 1945. Breeding for Resistance and Susceptibility to Avian Lymphomatosis. Poult. Sci. 24:259-269.