Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing.
Wee BA, Alves J, Lindsay DSJ, Klatt AB, Sargison FA, Cameron RL, Pickering A, Gorzynski J, Corander J, Marttinen P, Opitz B, Smith AJ, Fitzgerald JR. Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing. Nat Commun. 2021 Dec 9;12(1):7165. doi: 10.1038/s41467-021-27478-z. PMID: 34887398.
Evolutionary and functional analysis of coagulase positivity among the staphylococci.
Pickering AC, Yebra G, Gong X, Goncheva MI, Wee BA, MacFadyen AC, Muehlbauer LF, Alves J, Cartwright RA, Paterson GK, Fitzgerald JR. Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci. mSphere. 2021 Aug 25;6(4):e0038121. doi: 10.1128/mSphere.00381-21. Epub 2021 Aug 4. PMID: 34346700; PMCID: PMC8386474.
Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients.
Liu Y, Ling L, Wong SH, Wang MH, Fitzgerald JR, Zou X, Fang S, Liu X, Wang X, Hu W, Chan H, Wang Y, Huang D, Li Q, Wong WT, Choi G, Zou H, Hui DS, Yu J, Tse G, Gin T, Wu WK, Chan MT, Zhang L. Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients. EClinicalMedicine. 2021 Jun 10;37:100955. doi: 10.1016/j.eclinm.2021.100955. PMID: 34386745; PMCID: PMC8343259.
Radical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen.
Yebra G, Haag AF, Neamah MM, Wee BA, Richardson EJ, Horcajo P, Granneman S, Tormo-Más MÁ, de la Fuente R, Fitzgerald JR, Penadés JR. Radical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen. PLoS Pathog. 2021 May 20;17(5):e1009606. doi: 10.1371/journal.ppat.1009606. PMID: 34015034; PMCID: PMC8171923.
Staphylococcus aureus secreted lipases do not inhibit innate immune killing mechanisms.
Advances in transposon mutagenesis of staphylococcus aureus: insights into pathogenesis and antimicrobial resistance.
The role of gram-positive surface proteins in bacterial niche- and host-specialization.
A case report: insights into reducing plastic waste in a microbiology laboratory.
Population analysis of staphylococcus aureus reveals a cryptic, highly prevalent superantigen SElW that contributes to the pathogenesis of bacteremia.
Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model.
One Health: a multifaceted concept combining diverse approaches to prevent and control antimicrobial resistance.
Staphylococcus aureus lipase 1 enhances influenza A virus replication.
Developing novel host-based therapies targeting microbicidal responses in macrophages and neutrophils to combat bacterial antimicrobial resistance.
Metagenomic sequencing of clinical samples reveals a single widespread clone of Lawsonia intracellularis responsible for porcine proliferative enteropathy.
A multihost bacterial pathogen overcomes continuous population bottlenecks to adapt to new host species.
Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion.
Gene exchange drives the ecological success of a multi-host bacterial pathogen.
Population genomics of bacterial host adaptation.
The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function.
Population Genomics of Legionella longbeachae and Hidden Complexities of Infection Source Attribution.
Evolutionary Dynamics of Pandemic Methicillin-Sensitive Staphylococcus aureus ST398 and Its International Spread via Routes of Human Migration.
Genomics of Natural Populations of Staphylococcus aureus.
Identification of source and sink populations for the emergence and global spread of the East-Asia clone of community-associated MRSA.
Recombination-mediated remodelling of host-pathogen interactions during Staphylococcus aureus niche adaptation.
A single natural nucleotide mutation alters bacterial pathogen host tropism.
Gene flow in environmental Legionella pneumophila leads to genetic and pathogenic heterogeneity within a Legionnaires' disease outbreak.
Time-Scaled Evolutionary Analysis of the Transmission and Antibiotic Resistance Dynamics of Staphylococcus aureus Clonal Complex 398.
High-throughput sequencing for the study of bacterial pathogen biology.
Staphylococcus aureus proteins SSL6 and SElX interact with neutrophil receptors as identified using secretome phage display.
Livestock origin for a human pandemic clone of community-associated methicillin-resistant Staphylococcus aureus.
A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic.
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