Laboratory for Bacterial Evolution and Pathogenesis (LBEP)


Selected articles

Staphylococcus aureus secreted lipases do not inhibit innate immune killing mechanisms.

Advances in transposon mutagenesis of staphylococcus aureus: insights into pathogenesis and antimicrobial resistance.

The role of gram-positive surface proteins in bacterial niche- and host-specialization.

Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model.

Developing novel host-based therapies targeting microbicidal responses in macrophages and neutrophils to combat bacterial antimicrobial resistance.

Metagenomic sequencing of clinical samples reveals a single widespread clone of Lawsonia intracellularis responsible for porcine proliferative enteropathy.

A multihost bacterial pathogen overcomes continuous population bottlenecks to adapt to new host species.

Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion.

Bovine Staphylococcus aureus superantigens stimulate the entire T cell repertoire of cattle.

Population genomics of bacterial host adaptation.

Population Genomics of Legionella longbeachae and Hidden Complexities of Infection Source Attribution.

Evolutionary Dynamics of Pandemic Methicillin-Sensitive Staphylococcus aureus ST398 and Its International Spread via Routes of Human Migration. 

Genomics of Natural Populations of Staphylococcus aureus.

Identification of source and sink populations for the emergence and global spread of the East-Asia clone of community-associated MRSA. 

Gene flow in environmental Legionella pneumophila leads to genetic and pathogenic heterogeneity within a Legionnaires' disease outbreak.

Time-Scaled Evolutionary Analysis of the Transmission and Antibiotic Resistance Dynamics of Staphylococcus aureus Clonal Complex 398.

High-throughput sequencing for the study of bacterial pathogen biology.

Staphylococcus aureus proteins SSL6 and SElX interact with neutrophil receptors as identified using secretome phage display. 

Livestock origin for a human pandemic clone of community-associated methicillin-resistant Staphylococcus aureus.

Molecular dating of human-to-bovid host jumps by Staphylococcus aureus reveals an association with the spread of domestication. 

Livestock-associated Staphylococcus aureus: origin, evolution and public health threat. 

A structural model of the Staphylococcus aureus ClfA-fibrinogen interaction opens new avenues for the design of anti-staphylococcal therapeutics. 

Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health. 

Complete list of Prof Ross Fitzgerald publications (Google Scholar)