Centre for Regenerative Medicine

Pierre Bagnaninchi Research Group

Cell and tissue monitoring

Cell and tissue monitoring

Our main research interest is the development of label-free quantitative technologies to map biophysical properties (mechanical, optical, flow, electrical) of cells and tissues. They also address the need for real-time monitoring of 3D (spheroids, organoids) in vitro disease models, and the need to monitor tissue repair in pre-clinical studies. To this end, we currently investigate optical coherence tomography, impedance sensing and their combination into organ-on-a chip technologies with a focus on ophthalmological applications.

Dr Pierre Bagnaninchi

Group Leader

  • Centre for Regenerative Medicine

Contact details

We currently have projects on:

  1. Optical coherence tomography for tissue engineering and regenerative medicine 
    1. Measuring the mechanical properties of cells and tissues by optical means
  2. Noninvasive biosensors and quantitative methods in medicine and biology:
    1.  Label-free Impedance-based cellular assays (ECIS, EIT)
    2. Label-free 3D optical toxicity assays
  3. Organ-on-a-chip models of age-related macular degeneration

Pierre Bagnaninchi is a member of EPSRC, BBSRC and MRC funded Organ on a chip technologies network (www.organonachip.org.uk), for which he leads a Special interest group: Label-free real-time monitoring, translation to organ on a chip.

 

Group Members

 

Zhou Chen (PhD student)

Amelia Hallas-Potts (PhD Student)

Dawn Gillies (PhD Student)

Jonathan Mason (Post doc) 

Ryoma Ogawa (Tobitate Young Ambassador Japan) 

Ege Kaan Ozkaya (PhD Student)

Clara Vergez (PhD Student)

Hason Wu (PhD Student)

Jiwan Park (PhD Student)

 

Funders