Centre for Regenerative Medicine

High Content Screening

The High Content Screening facility contains equipment for assay development (throughput and miniaturisation), high throughput imaging and subsequent high content data analysis for internal and external users.

The facility provides the potential for a complete semi-automated workflow for increased assay throughput and screening. This includes sterile cell seeding and media changes, reagent addition and staining of 96 and 384 well plates. Imaging and analysis can be performed on any multiwell plates (6-1584 well) or slides. An example workflow is shown in the schematic. Equipment can also be reconfigured and booked independently for custom workflows.  

The facility is spread between imaging (G.46 & G.45) and a high throughput cell culture room (1.52). Samples of multi-well plates and dyes are available upon request.

Dr Justyna Cholewa-Waclaw

High Content Screening Facility Manager

  • Centre for Regenerative Medicine
  • Institute for Regeneration and Repair

Contact details

Operetta high content microscope

An automated microscope for high content imaging

Multidrop (bench)

Bulk liquid dispense

Multidrop (sterile)

Multidrop (sterile)

ViaFlo

Lightweight electronic pipettes

Cy Bio FeliX

A flexible and fully automatic multi-channel pipetting robot

BioTek 405 Platewasher

A deep well microplate washer that aspirates and dispenses into 96- and 384-well plates

Columbus Image analysis server

Slide and multiwell plate image analyser

Vectra Polaris Automated Quantitative Pathology Imaging System

Imaging system which enables identification and quantification of multiple biomarkers