Rm. 1.13, Ashworth Building
- Post code
1981 PhD in Immunology, Department of Pathology, University of Cambridge
1981-1984 Postdoctoral Research Assistant, Department of Pathology, University of Cambridge
1984-1987 Postdoctoral Research Fellow, Dept. of Medicine, Stanford University, U.S.A.
1987-1991 Research Scientist, ICRF, Tumour Immunology Unit, University College London
1991-2007 Senior Research Scientist, MRC National Institute for Medical Research, Mill Hill, London
2007-present Professor of Immune Cell Biology, University of Edinburgh
We are interested in understanding how T lymphocytes communicate with their environment both during differentiation in the thymus and subsequently in the periphery to regulate survival, expansion and further differentiation into effector or memory cells, while maintaining tolerance. In particular we are focussed on the role of the Src-kinase family and their modifiers such as the phosphatase, PTPN22, in facilitating responsiveness to antigens while retaining tolerance to self-proteins.