Rose Zamoyska


1981    PhD in Immunology, Department of Pathology, University of Cambridge

1981-1984    Postdoctoral Research Assistant, Department of Pathology, University of Cambridge

1984-1987    Postdoctoral Research Fellow, Dept. of Medicine, Stanford University, U.S.A.

1987-1991    Research Scientist, ICRF, Tumour Immunology Unit, University College London

1991-2007    Senior Research Scientist, MRC National Institute for Medical Research, Mill Hill, London

2007-present    Professor of Immune Cell Biology, University of Edinburgh

Research summary

We are interested in understanding how T lymphocytes communicate with their environment both during differentiation in the thymus and subsequently in the periphery to regulate survival, expansion and further differentiation into effector or memory cells, while maintaining tolerance. In particular we are focussed on the role of the Src-kinase family and their modifiers such as the phosphatase, PTPN22, in facilitating responsiveness to antigens while retaining tolerance to self-proteins.