Professor Andrew McIntosh
Chair of Biological Psychiatry
Division of Psychiatry
University of Edinburgh
Royal Edinburgh Hospital
- Post code
- EH10 5HF
Andrew McIntosh is a Professor of Psychiatry at the Division of Psychiatry, Centre for Clinical Brain Sciences.
Prof McIntosh trained in Medicine at the University of Aberdeen before completing his postgraduate training in Edinburgh in Psychiatry and in Applied Statistics. He leads the Generation Scotland Expert Working Group for Psychiatric Disorders and co-chairs the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC).
- 1995, Bachelor of Medicine and Bachelor of Surgery, University of Aberdeen
- 1992, Bachelor of Science (Hons), University of Aberdeen
- 2004, Master of Science, Edinburgh Napier University
- 2000, Master of Philosophy, University of Edinburgh
- 2004, Doctor of Medicine, University of Edinburgh
- 2012, Fellow of the Royal College of Psychiatrists, FRCPsych
- 1999, Member of The Royal College of Psychiatrists, MRCPsych
Responsibilities & affiliations
- Chair of Generation Scotland Mental Health Expert Working Group
- Co-chair of Psychiatric Genomics Consortium Major Depressive Disorder Working Group
- Associate Director of the NRS Mental Health network
- Ad-hoc member of Wellcome Trust Review Groups and Fellowships Committee
- Chair of MQ Mental Health Data Science Group
- Rotating Chair of UK Biobank Mental Health Genetic Group
Open to PhD supervision enquiries?
Professor McIntosh seeks to better understand the causes and consequences of depression and resilience . He uses a number of methods including: genetic analysis, NHS data linkage, clinical and cogntive measurement and brain imaging.
Current research interestsDepression and psychological resilience The genetic and environmental causes of depression The mechanisms and causal consequences of depression Public enagagement around the use of mental health data in research
Professor McIntosh is closely inviolved in several public enagagement activities, which include:
- Public enagagement around the use of NHS data in research
- Public engagement around the value of large population-based studies such as Generation Scotland and UK Biobank
- Knowledge exchange activities around depression research, including "Big Data Detectives" (Edinburgh Science Festival, 2019)
- Work with schools and young people around depression and resilience
Current project grants
04036/Z/14/Z; McIntosh AM (PI) 2015-2019; Wellcome Trust Strategic Award; “Stratifying Resilience and Depression Longitudinally”
MR/S035818/1; McIntosh AM (PI) 2019-2024; MRC Global Challenge Research Fund Award: “Generation Malawi: A study of family, maternal and childhood mental health”
MC_PC_17209; McIntosh AM (PI) 2018-2020; MRC Mental Health Pathfinder Award: “Leveraging routinely collected and linked research data to study the causes and consequences of common mental disorders”
MR/R023484/1; Elliot (PI) McIntosh AM (CoI) et al 2018-2023; MRC Programme Grant "The Airwave Health Monitoring Study (AHMS). An Occupational Cohort Study of the British Police Forces"
Uncovering the genetic architecture of major depression
Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
Parent of origin genetic effects on methylation in humans are common and influence complex trait variation
An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort
Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing
How data science can advance mental health research