Prof David Argyle
Vice Principal and Head of College of Medicine & Veterinary, College of Medicine and Veterinary Medicine
Contact details
Address
- Street
-
The Royal (Dick) School of Veterinary Studies
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Background
David Argyle is a graduate of Veterinary Medicine and Surgery from the University of Glasgow. He gained his PhD in Immunology and Oncology from the same faculty.
He has served as a clinical academic for the universities of Glasgow, Wisconsin-Madison and Edinburgh. He is an RCVS and European-recognised specialist in veterinary oncology and his major interests are cancer biology and comparative oncology.
In 2011, he was appointed William Dick chair of Veterinary Clinical Studies and Dean of Veterinary Medicine at The Royal (Dick) School of Veterinary Studies. In 2022, he was appointed to be Vice Principal and Head of College of Medicine and Veterinary Medicine at the University of Edinburgh.
He is a Fellow of the Royal College of Veterinary Surgeons, Fellow of the Royal Society of Edinburgh and a Fellow of the Royal Society for the Arts.
Collaborative Activity
Professor Ted Hupp
Professor Steve McLaughlin (Heriot-Watt University)
Professor Mark Bradley
Professor Andy Mount
Professor Ian Kunkler
Dr. Simon Langdon
Professor Joyce Tait (Innogen)
Dr. Jan Mol (Utrecht)
Qualifications
Doctor of Philosophy (PhD), University of Glasgow Cloning, Sequencing, Expression and Characterization of Feline Interferon-Gamm Bachelor of Veterinary Medicine & Surgery, University of Glasgow
Professional Qualifications
Diplomate of the European College of Veterinary Internal Medicine, DECVIM-CA (Oncology) Member of the Royal College of Veterinary Surgeons (Register Index Number: 6191897), MRCVS
Responsibilities & affiliations
Head of School
Research summary
Mechanistic studies into canine disease, specifically the focus of my research is comparative cancer biology. This involves studies on the stem cell basis of cancer through to the translation of new therapeutics into clinical development.
Current research interests
The Comparative Oncology and Stem Cell Research Group is a multidisciplinary team that draws its expertise from both clinical and laboratory trained staff and is further augmented by collaborations within the Edinburgh area research community (University of Edinburgh cancer research centre, The Roslin Institute) the USA and EU. Our approach to the integration of laboratory and clinical research make us well placed to carry out high quality translational studies. Many of the group members are also faculty members of the Royal (Dick) School of Veterinary Studies.-
Use of multi-color flow cytometry for canine immune cell characterization in cancer
(15 pages)
In:
PLoS ONE, vol. 18, pp. 1-15
DOI: https://doi.org/10.1371/journal.pone.0279057
Research output: Contribution to Journal › Article (Published) -
Improving livestock genetics to enhance animal welfare and production for African smallholder farmers
In:
American Journal of Veterinary Research, vol. 84
DOI: https://doi.org/10.2460/ajvr.22.11.0199
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Association of fecal and serum microRNA profiles with gastrointestinal cancer and chronic inflammatory enteropathy in dogs
In:
Journal of Veterinary Internal Medicine, vol. 36, pp. 1989-2001
DOI: https://doi.org/10.1111/jvim.16530
Research output: Contribution to Journal › Article (Published) -
Correction: Canine Mammary Cancer Stem Cells Are Radio- and Chemo- Resistant and Exhibit an Epithelial-Mesenchymal Transition Phenotype.
In:
Cancers, vol. 14
DOI: https://doi.org/10.3390/cancers14174242
Research output: Contribution to Journal › Article (Published) -
Effective Penetration of a Liposomal Formulation of Bleomycin through Ex-Vivo Skin Explants from Two Different Species
In:
Cancers, vol. 14
DOI: https://doi.org/10.3390/cancers14041083
Research output: Contribution to Journal › Article (Published) -
Exosomes Derived from Radioresistant Breast Cancer Cells Promote Therapeutic Resistance in Naïve Recipient Cells
In:
Journal of personalized medicine
DOI: https://doi.org/10.3390/jpm11121310
Research output: Contribution to Journal › Special issue (E-pub ahead of print) -
In vivo application of an implantable tri-anchored methylene blue-based electrochemical pH sensor
In:
Biosensors & Bioelectronics, pp. 113728
DOI: https://doi.org/10.1016/j.bios.2021.113728
Research output: Contribution to Journal › Article (E-pub ahead of print) -
REV1 Inhibition Enhances Radioresistance and Autophagy
In:
Cancers, vol. 13
DOI: https://doi.org/10.3390/cancers13215290
Research output: Contribution to Journal › Article (Published) -
Corrigendum to "Feline mammary carcinoma stem cells are tumorigenic, radioresistant, chemoresistant and defective in activation of the ATM/p53 DNA damage pathway" [The Veterinary Journal 196 (2013) 414-423]
In:
The Veterinary Journal, vol. 276, pp. 105744
DOI: https://doi.org/10.1016/j.tvjl.2021.105744
Research output: Contribution to Journal › Comment/debate (E-pub ahead of print) -
COX-2 Silencing in Canine Malignant Melanoma Inhibits Malignant Behaviour
In:
Frontiers in Veterinary Science, vol. 8
DOI: https://doi.org/10.3389/fvets.2021.633170
Research output: Contribution to Journal › Article (E-pub ahead of print)