Oriol Canela Xandri
RCUK Innovation/ Rutherford Fund Fellowships
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Research summary
Developing methods for understanding how genes are related to the development of different traits.
Current research interests
Understanding how genes influence the observed phenotypes in human populations is relevant in many fields. In particular, this can help to improve the population health. Our research is focused on developing new methods that will allow a better understanding of the linking between genotypes and the corresponding phenotypes. In the future this will help to predict which diseases individuals could develop and which drugs and preventative treatments could be applied for best results.-
Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes
(13 pages)
In:
Communications biology, vol. 6, pp. 1-13
DOI: https://doi.org/10.1038/s42003-023-04836-9
Research output: Contribution to Journal › Article (Published) -
Reply to: Genotype by sex interactions in ankylosing spondylitis
(2 pages)
In:
Nature Genetics, vol. 55, pp. 17-18
DOI: https://doi.org/10.1038/s41588-022-01251-4
Research output: Contribution to Journal › Article (Published) -
Sex differences in genetic architecture in the UK Biobank
(7 pages)
In:
Nature Genetics, vol. 53, pp. 1283-1289
DOI: https://doi.org/10.1038/s41588-021-00912-0
Research output: Contribution to Journal › Article (Published) -
Evidence of horizontal indirect genetic effects in humans
In:
Nature Human Behaviour
DOI: https://doi.org/10.1038/s41562-020-00991-9
Research output: Contribution to Journal › Article (Published) -
Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits
In:
PLoS Genetics, vol. 16
DOI: https://doi.org/10.1371/journal.pgen.1008785
Research output: Contribution to Journal › Article (Published) -
Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle
In:
Genome Research
DOI: https://doi.org/10.1101/gr.250704.119
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Statistical and Functional Studies Identify Epistasis of Cardiovascular Risk Genomic Variants From Genome-Wide Association Studies
In:
Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, vol. 9, pp. e014146
DOI: https://doi.org/10.1161/JAHA.119.014146
Research output: Contribution to Journal › Article (Published) -
A comprehensive catalogue of regulatory variants in the cattle transcriptome
In:
bioRxiv
Research output: Contribution to Journal › Article (Published) -
Indirect assortative mating for human disease and longevity
In:
Heredity
DOI: https://doi.org/10.1038/s41437-019-0185-3
Research output: Contribution to Journal › Article (Published) -
Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation
In:
Nature Communications, vol. 10, pp. 2069
DOI: https://doi.org/10.1038/s41467-019-10155-7
Research output: Contribution to Journal › Article (Published)