Nicholas Mullin
Contact details
- Tel: 0131 651 9560/9561
- Email: nick.mullin@ed.ac.uk
Address
- Street
-
Centre for Regenerative Medicine
Institute for Regeneration and Repair
The University of Edinburgh
Edinburgh BioQuarter
5 Little France Drive - City
- Edinburgh
- Post code
- EH16 4UU
-
Phosphorylation of NANOG by CASEIN KINASE I regulates embryonic stem cell self-renewal
(12 pages)
In:
FEBS Letters, vol. 595, pp. 14-25
DOI: https://doi.org/10.1002/1873-3468.13969
Research output: Contribution to Journal › Article (Published) -
TET1 interacts directly with NANOG via independent domains containing hydrophobic and aromatic residues
In:
Journal of Molecular Biology, vol. 432, pp. 6075-6091
DOI: https://doi.org/10.1016/j.jmb.2020.10.008
Research output: Contribution to Journal › Article (Published) -
Distinct SoxB1 networks are required for naïve and primed pluripotency
(28 pages)
In:
eLIFE, vol. 6
DOI: https://doi.org/10.7554/eLife.27746
Research output: Contribution to Journal › Article (Published) -
A new twist to Sin3 complexes in pluripotent cells
In:
EMBO Journal
DOI: https://doi.org/10.15252/embj.201797516
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function
In:
Journal of Molecular Biology
DOI: https://doi.org/10.1016/j.jmb.2016.12.001
Research output: Contribution to Journal › Article (Published) -
The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells
In:
Genes and Development
DOI: https://doi.org/10.1101/gad.275685.115
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal
(17 pages)
In:
EMBO Journal, vol. 32, pp. 2231-47
DOI: https://doi.org/10.1038/emboj.2013.161
Research output: Contribution to Journal › Article (Published) -
Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog
(15 pages)
In:
Cell Stem Cell, vol. 12, pp. 531-45
DOI: https://doi.org/10.1016/j.stem.2013.04.023
Research output: Contribution to Journal › Article (Published) -
OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells
(16 pages)
In:
EMBO Journal, vol. 31, pp. 4547-4562
DOI: https://doi.org/10.1038/emboj.2012.321
Research output: Contribution to Journal › Article (Published) -
The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells
(10 pages)
In:
Human Genetics, vol. 130, pp. 255-264
DOI: https://doi.org/10.1007/s00439-011-0998-5
Research output: Contribution to Journal › Article (Published) -
An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
(13 pages)
In:
Cell Stem Cell, vol. 6, pp. 369-381
DOI: https://doi.org/10.1016/j.stem.2010.02.014
Research output: Contribution to Journal › Article (Published) -
The pluripotency rheostat Nanog functions as a dimer
(5 pages)
In:
Biochemical Journal, vol. 411, pp. 227-231
DOI: https://doi.org/10.1042/BJ20080134
Research output: Contribution to Journal › Article (Published) -
Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein
(17 pages)
In:
Journal of Molecular Biology, vol. 307, pp. 323-339
Research output: Contribution to Journal › Article (Published) -
Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
(11 pages)
In:
Cell, vol. 104, pp. 301-311
Research output: Contribution to Journal › Article (Published) -
Conserved Surface-Exposed K/R-X-K/R Motifs and Net Positive Charge on Poxvirus Complement Control Proteins Serve as Putative Heparin Binding Sites and Contribute to Inhibition of Molecular Interactions with Human Endothelial Cells: a Novel Mechanism for Evasion of Host Defense
(8 pages)
In:
Journal of Virology, vol. 74, pp. 5659-5666
DOI: https://doi.org/10.1128/JVI.74.12.5659-5666.2000
Research output: Contribution to Journal › Article (Published)