Mr Steven Wright
Senior Research Technician
Contact details
Address
- Street
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The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
I am currently working in the Roslin Institute as core scientist in Dr David Collie’s research group. We are part of the larger Gene Therapy Group with research interests in the causes and treatments of lung disease. Our current research focus is on developing strategies to mitigate the risk of radiation-induced lung injury. We have further interests in how microbial communities develop within the healthy lung and the changes caused by chronic infection. These interests complement our involvement within the UK Cystic Fibrosis Gene Therapy Consortium in developing lung-directed gene therapy. My previous laboratory experience was in helminthology research, where I was involved in developing a serodiagnostic assay for screening herds of cattle for cysticercosis infection. I also worked on research into mast cells and their involvement in the expulsion of nematodes from the gut.
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Regional and organ-level responses to local lung irradiation in sheep
In:
Scientific Reports
DOI: https://doi.org/10.1038/s41598-021-88863-8
Research output: Contribution to Journal › Article (Published) -
Effects of direct lung dosing of Tobramycin in a rat chronic infection model using Pseudomonas aeruginosa RP73
(3 pages)
In:
European Respiratory Journal, vol. 52
DOI: https://doi.org/10.1183/13993003.congress-2018.PA2656
Research output: Contribution to Journal › Meeting abstract (Published) -
Nebulisation of synthetic lamellar lipids mitigates radiation-induced lung injury in a large animal model
In:
Scientific Reports, vol. 8
DOI: https://doi.org/10.1038/s41598-018-31559-3
Research output: Contribution to Journal › Article (Published) -
Rat Model of Chronic Lung Infection Using Pseudomonas Strain RP73
(2 pages)
In:
American Journal of Respiratory and Critical Care Medicine, vol. 197
Research output: Contribution to Journal › Meeting abstract (Published) -
Comparing microbiotas in the upper aerodigestive and lower respiratory tracts of lambs
In:
Microbiome, vol. 5
DOI: https://doi.org/10.1186/s40168-017-0364-5
Research output: Contribution to Journal › Article (Published) -
Microbiota in Exhaled Breath Condensate and the Lung
In:
Applied and Environmental Microbiology, vol. 83
DOI: https://doi.org/10.1128/AEM.00515-17
Research output: Contribution to Journal › Article (Published) -
Variability of the Sheep Lung Microbiota
In:
Applied and Environmental Microbiology, vol. 82, pp. 3225-3238
DOI: https://doi.org/10.1128/AEM.00540-16
Research output: Contribution to Journal › Article (Published) -
Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact of Intravenous Colistimethate Sodium
In:
PLoS ONE, vol. 10, pp. e0142097
DOI: https://doi.org/10.1371/journal.pone.0142097
Research output: Contribution to Journal › Article (Published) -
A Lung Segmental Model of Chronic Pseudomonas Infection in Sheep
In:
PLoS ONE, vol. 8
DOI: https://doi.org/10.1371/journal.pone.0067677
Research output: Contribution to Journal › Article (Published) -
The Goblet Cell Is the Cellular Source of the Anti-Microbial Angiogenin 4 in the Large Intestine Post Trichuris muris Infection
(7 pages)
In:
PLoS ONE, vol. 7, pp. -
DOI: https://doi.org/10.1371/journal.pone.0042248
Research output: Contribution to Journal › Article (Published)