Mr Maciej Parys | The University of Edinburgh

Vet Clinical Lectureship

Email: mparys@exseed.ed.ac.uk
Web: University of Edinburgh Research Explorer Profile

Street: The Royal (Dick) School of Veterinary Studies and The Roslin Institute
Easter Bush
Midlothian
City
Post code: EH25 9RG

Biography

Background

I have graduated from University of Warmia and Mazury in Olsztyn, Poland in 2009. Subsequently I worked in private practice. In 2010 I have started PhD at Michigan State University, College of Veterinary Medicine. During my PhD I was studying immunomodulatory properties of feline mesenchymal stem cells and their clinical application in chronic feline idiopathic cystitis. In 2016 I relocated to R(D)SVS to start a clinical lecturership position, which combines work in small animal internal medicine with research on identifying novel approaches to cancer immunotherapy. My research interests also include therapeutic use of stem cells in companion animals, use of next generation sequencing to identify disease causing genetic variants and pathways involved in disease pathogenesis in companion animals. In 2016 I was awarded an AVMA/AVMF Young Investigator Award for work on immunomodulatory properties of feline mesenchymal stem cells. In 2017 I was awarded an ABCD and Boeringher Ingelheim Young Scientist Award.

Qualifications

2010 Doctor of Philosophy (PhD), Michigan State University Evaluation of immunomodulatory properties of feline mesenchymal stem cells and their clinical application in treatment of feline chronic idiopathic cystitis

2004 University of Warmia and Mazury

Research

Research summary

My current research interests include studying the role of immune checkpoints in canine and feline cancer and inflammatory disease. I am also intereted in interactions between innate and adaptive immune system in cancer patients.

Current research interests

Cancer immunotherapy, therapeutic use of mesenchymal stem cells, immunology, personalized medicine, use of next generation sequencing to identify disease causing variants and pathways

Research activities

CT features of feline lipiduria and renal cortical lipid deposition 1 Nov 2019

View activity on Research Explorer

Publications

Hyperprogression Under Immune Checkpoint-Based Immunotherapy—Current Understanding, The Role of PD-1/PD-L1 Tumour-Intrinsic Signalling, Future Directions and a Potential Large Animal Model 27 Mar 2020 In: Cancers
DOI: https://doi.org/10.3390/cancers12040804
Research output: Contribution to Journal › Article (E-pub ahead of print)
Computed Tomography Retrograde Urethrography 24 Apr 2019
Research output: Contribution to Symposium › Poster (Published)
Dynamic Contrast-Enhanced Magnetic Resonance Imaging of OATP Dysfunction in Diabetes 28 Nov 2018 In: Diabetes
DOI: https://doi.org/10.2337/db18-0525
Research output: Contribution to Journal › Article (Published)
Diagnostic quality of computed tomographic retrograde urethrography in male dogs (1 page) 9 Nov 2018
Research output: Contribution to Conference › Abstract (Published)
Investigation of novel chemotherapeutics for feline oral squamous cell carcinoma 4 Sep 2018 In: Oncotarget, vol. 9, pp. 33098-33109
DOI: https://doi.org/10.18632/oncotarget.26006
Research output: Contribution to Journal › Article (Published)
A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies 1 Mar 2018 In: BMC Cancer, vol. 18, pp. 237
DOI: https://doi.org/10.1186/s12885-018-4132-0
Research output: Contribution to Journal › Article (Published)
Serum Cytokine Profiling in Cats with Acute Idiopathic Cystitis 22 Jan 2018 In: Journal of Veterinary Internal Medicine, vol. 32, pp. 274-279
DOI: https://doi.org/10.1111/jvim.15032
Research output: Contribution to Journal › Article (E-pub ahead of print)
OVARIAN ADENOCARCINOMA IN JAGUARS ( PANTHERA ONCA ): A NATURALLY-OCCURRING MODEL OF HUMAN INHERITED OVARIAN CANCER? 31 May 2017 In: Clinical Cancer Research, vol. 23
Research output: Contribution to Journal › Meeting abstract (Published)
Evaluation of immunomodulatory properties of feline mesenchymal stem cells 9 Feb 2017 In: Stem Cells and Development
DOI: https://doi.org/10.1089/scd.2016.0041
Research output: Contribution to Journal › Article (Published)
In Vivo Microcomputed Tomography of Nanocrystal-Doped Tissue Engineered Scaffolds (9 pages) 29 Feb 2016 In: ASC Biomaterials Science & Engineering, vol. 2, pp. 508-516
DOI: https://doi.org/10.1021/acsbiomaterials.5b00476
Research output: Contribution to Journal › Article (E-pub ahead of print)

View all 18 publications on Research Explorer

This article was published on 18 Oct, 2020