Linda Mullins

Research Fellow

  • Centre for Cardiovascular Science

Contact details



Queens Medical Research Institute
Edinburgh Bioquarter
47 Little France Crescent

Post code
EH16 4TJ

Research summary

Over the last 25 years I have been involved in the generation and characterisation of transgenic mouse and rat models - using microinjection with BACs, ES cell gene knock-out and blastocyst injection, and more recently using genome engineering with ZFN and CRISPR-Cas9 technologies. Gene targets have included renin, 11 B-hydroxylase and hydroxysteroid dehydrogenase type 2. The models have been extensively characterised for renal function, blood pressure and aspects of metabolism. I am currently planning CRISPR-Cas 9 targeting experiments in zebrafish

View all 48 publications on Research Explorer