Dr Liam Morrison
Senior Research Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Qualifications
Doctor of Philosophy (PhD), University of Glasgow The dynamics and nature of the hierarchical expression of VSGs during Trypanosoma brucei infection. Bachelor of Veterinary Medicine & Surgery, University of Glasgow Bachelor of Science, University of Glasgow
Professional Qualifications
2000Member of the Royal College of Veterinary Surgeons, MRCVS
Undergraduate teaching
MSc Animal Bioscience
One Health, Zoonoses and Emerging Infections
Module co-ordinator and member of Examiner's Board
Research summary
I am interested in the infection biology of protozoan parasites of livestock. I am particularly attracted to integrated approaches where we can learn about both host and parasite processes that are key to infection/disease progression – especially in the clinically relevant host, the cow. I work primarily on African trypanosomes, but also on Theileria parva , which together are the most significant pathogens affecting livestock in sub-Saharan Africa. I also work on Cryptosporidium parvum, a worldwide enteric pathogen of humans and livestock. My work aims to identify key host-parasite interactions that determine disease outcome, further our understanding of bovine immunobiology, and identify targets for interventions (e.g. drug & vaccine development).
Current research interests
PhD (*primary supervisor)Charlotte McCarroll (University of Glasgow) 2010-2014Alison Burrells (Moredun Research Institute) 2010-2014Olumide Ajibola (University of Glasgow) 2011-2015Heli Vaikinnen (University of Glasgow) 2011-2016Omar Alfituri (Roslin Institute) 2014-2018Hannah Shaw (Moredun Research Institute) 2015-2019*Fiona Allan (Roslin Institute) 2015-2019Kirsty McWilliam (University of Edinburgh) 2015-2019*Jessica Powell (Roslin Institute) 2016-2020*James Iremonger (Roslin Institute) 2017-2020MScKeely Young (Moredun Research Institute) 2013-2014-
Antigenic diversity in Theileria parva populations from sympatric cattle and African buffalo analysed using long read sequencing
In:
Frontiers in genetics
DOI: https://doi.org/10.3389/fgene.2021.684127
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition
In:
PLoS Pathogens
Research output: Contribution to Journal › Article (Accepted/In press) -
Genetic diversity and shedding profiles for Cryptosporidium parvum in adult cattle and their calves
In:
Current Research in Parasitology & Vector-Borne Diseases
DOI: https://doi.org/10.1016/j.crpvbd.2021.100027
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Dermal bacterial LPS-stimulation reduces susceptibility to intradermal Trypanosoma brucei infection
In:
Scientific Reports
DOI: https://doi.org/10.1038/s41598-021-89053-2
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Pharma to Farmer: Field Challenges of Optimizing Trypanocide use in African Animal Trypanosomiasis
In:
Trends in Parasitology
DOI: https://doi.org/10.1016/j.pt.2021.04.007
Research output: Contribution to Journal › Article (Published) -
Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential
In:
Molecular Biology
DOI: https://doi.org/10.1111/mmi.14733
Research output: Contribution to Journal › Article (Published) -
Corrigendum to "Inverted CD4 +/CD8+T cell ratio in Boran (Bos indicus) cattle" [Vet. Immunol. Immunopathol. 230 110126]
In:
Veterinary Immunology and Immunopathology
DOI: https://doi.org/10.1016/j.vetimm.2021.110219
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo
In:
PLoS Pathogens
DOI: https://doi.org/10.1371/journal.ppat.1009224
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs
In:
PLoS Pathogens, vol. 16
DOI: https://doi.org/10.1371/journal.ppat.1008932
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Contrasting population genetics of co-endemic cattle- and buffalo- derived Theileria annulata
In:
Ticks and tick-borne diseases
DOI: https://doi.org/10.1016/j.ttbdis.2020.101595
Research output: Contribution to Journal › Article (E-pub ahead of print)