Karin Purshouse
PhD supervisors:
Background
I am a Medical Oncology Registrar currently undertaking a PhD in Regenerative Medicine.
I am the Clinical Outreach and Scotland Lead for the UK Coronavirus Cancer Monitoring project: https://ukcoronaviruscancermonitoring.com/
Qualifications
MBBS (Hons) - University of Newcastle upon Tyne, BSC (Hons) - Imperial College London, MSc - University of Edinburgh, PGCert Health Research - Oxford University, MRCP (Med Onc), FRSA
Responsibilities & affiliations
Honorary Specialty Registrar in Medical Oncology, NHS Lothian
Research summary
Current research interests
I am interested in the spatial regulation of gene expression and how this affects initiation and propagation of glioblatoma stem cells, having previously worked in the areas of DNA damage and hypoxia in cancer. Other current research: - Member of Project Management Group, UK Coronavirus Cancer Monitoring Project: https://ukcoronaviruscancermonitoring.com/ - Co-Principal Investigator Scottish COVID CAncer iMmunity Prevalence (SCCAMP) study: https://cancer-data.ecrc.ed.ac.uk/sccamp/ - Scotland lead for National Oncology Trainees Collaborative for Healthcare Research (NOTCH)Past research interests
Previous labs: Prof Adrian Harris - Oxford University - https://www.oncology.ox.ac.uk/team/adrian-harris, Prof Ester Hammond - Oxford University - https://www.oncology.ox.ac.uk/team/ester-hammond, Ass. Prof Ranjit Bindra - Yale University - https://bindralab.org/Knowledge exchange
Publications available at:
https://www.ncbi.nlm.nih.gov/pubmed/?term=purshouse+k
Current project grants
Wellcome Trust PhD Fellowship
Past project grants
NIHR Academic Clinical Fellow (Oxford University Hospitals NHS Foundation Trust)
Fulbright Postgraduate Award
-
The Scottish COVID Cancer Immunity Prevalence Study: A Longitudinal Study of SARS-CoV-2 Immune Response in Patients Receiving Anti–Cancer Treatment
In:
The Oncologist
DOI: https://doi.org/10.1093/oncolo/oyac257
Research output: Contribution to Journal › Article (Published) -
Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells
In:
eLIFE, vol. 11
DOI: https://doi.org/10.7554/eLife.80207
Research output: Contribution to Journal › Article (Published) -
Mortality among Adults with Cancer undergoing Chemotherapy or Immunotherapy Infected with COVID-19
In:
JAMA Network Open
DOI: https://doi.org/10.1001/jamanetworkopen.2022.0130
Research output: Contribution to Journal › Article (Published) -
Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19
In:
JAMA Network Open, vol. 5, pp. e220130
DOI: https://doi.org/10.1001/jamanetworkopen.2022.0130
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Characterisation and outcomes of patients referred to a regional cancer of unknown primary team: a 10-year analysis
In:
British Journal of Cancer
DOI: https://doi.org/10.1038/s41416-021-01544-1
Research output: Contribution to Journal › Article (Published) -
COVID-19 and cancer registries: Learning from the first peak of the SARS-CoV-2 pandemic
In:
British Journal of Cancer
DOI: https://doi.org/10.1038/s41416-021-01324-x
Research output: Contribution to Journal › Article (Published) -
COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study
In:
The Lancet Oncology
DOI: https://doi.org/10.1016/S1470-2045(20)30442-3
Research output: Contribution to Journal › Article (E-pub ahead of print) -
COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study
(8 pages)
In:
The Lancet, vol. 395, pp. 1919-1926
DOI: https://doi.org/10.1016/S0140-6736(20)31173-9
Research output: Contribution to Journal › Article (Published) -
Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?
In:
British Journal of Cancer
DOI: https://doi.org/10.1038/s41416-020-0930-7
Research output: Contribution to Journal › Comment/debate (Published) -
Distinguishing between direct and indirect consequences of covid-19
In:
British Medical Journal (BMJ), vol. 369, pp. m2377
DOI: https://doi.org/10.1136/bmj.m2377
Research output: Contribution to Journal › Letter (Published) -
The UK Coronavirus Cancer Monitoring Project: protecting patients with cancer in the era of COVID-19
In:
The Lancet Oncology, vol. 21, pp. 622-624
DOI: https://doi.org/10.1016/S1470-2045(20)30230-8
Research output: Contribution to Journal › Comment/debate (Published)