Julie Rodor
Senior Scientist
- Centre for Cardiovascular Science
Contact details
- Tel: 0131 242 6745
- Email: Julie.Rodor@igmm.ed.ac.uk
Address
- Street
-
Queens Medical Research Institute
Edinburgh Bioquarter
47 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4TJ
Research summary
I am working as a bioinformatician in the group of Professor Andrew Baker since March 2016. I am interested in the identification and characterization of long non-coding RNAs involved in vascular biology and disease, using computational approached. I am currently analysing several ‘vascular’ RNA-seq data obtained in Professor Andrew Baker’s group, such as the differentiation of human embryonic stem cells to endothelial cells as well as clinical studies linked to plaque instability. I would like to identify the lncRNAs that are differentially expressed during development or in pathology. Then, I would like to characterise their function, by integrating them into a gene expression network.
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Response to: Are endothelial cell proliferation and mesenchymal transition as distinguishing characteristics of three-week SuHx mice model?
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvad075
Research output: Contribution to Journal › Letter (E-pub ahead of print) -
INKILN is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10
In:
Circulation
Research output: Contribution to Journal › Article (Accepted/In press) -
Deciphering endothelial heterogeneity in health and disease at single cell resolution: progress and perspectives
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvac018
Research output: Contribution to Journal › Review article (Published) -
Nuclear S-nitrosylation impacts tissue regeneration in zebrafish
In:
Nature Communications
DOI: https://doi.org/10.1038/s41467-021-26621-0
Research output: Contribution to Journal › Article (Published) -
Single-cell RNA-seq profiling of mouse endothelial cells in response to pulmonary arterial hypertension
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvab296
Research output: Contribution to Journal › Article (Published) -
CARMN loss regulates smooth muscle cells and accelerates atherosclerosis in mice
In:
Circulation Research
DOI: https://doi.org/10.1161/CIRCRESAHA.120.318688
Research output: Contribution to Journal › Article (Published) -
MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease
In:
Circulation Research
DOI: https://doi.org/10.1161/CIRCRESAHA.120.318124
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Novel transcript discovery expands the repertoire of pathologically-associated, long non-coding RNAs in vascular smooth muscle cells
In:
International Journal of Molecular Sciences
DOI: https://doi.org/10.3390/ijms22031484
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Identifying cell enriched miRNAs in kidney injury and repair
In:
JCI Insight, vol. 5
DOI: https://doi.org/10.1172/jci.insight.140399
Research output: Contribution to Journal › Article (E-pub ahead of print) -
T-Cell–Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension
In:
Circulation Research, vol. 126, pp. 988–1003
DOI: https://doi.org/10.1161/CIRCRESAHA.119.315428
Research output: Contribution to Journal › Article (Published) -
The LINC00961 transcript and its encoded micropeptide SPAAR regulate endothelial cell function
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvaa008
Research output: Contribution to Journal › Article (Published) -
A Novel Plaque Enriched Long Noncoding RNA in Atherosclerotic Macrophage Regulation (PELATON)
In:
Arteriosclerosis, Thrombosis, and Vascular Biology
DOI: https://doi.org/10.1161/ATVBAHA.119.313430
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF-β signalling: implications for PAH vascular remodelling
In:
Cell communication and signaling, vol. 17
DOI: https://doi.org/10.1186/s12964-019-0449-9
Research output: Contribution to Journal › Article (Published) -
The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling.
In:
Circulation Research, vol. 125, pp. 535–551
DOI: https://doi.org/10.1161/CIRCRESAHA.119.314876
Research output: Contribution to Journal › Article (Published) -
Endothelial Function and Dysfunction in the Cardiovascular System: The Long Non-Coding Road
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvz154
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
The RNA-binding landscape of RBM10 and its role in alternative splicing regulation in models of mouse early development
In:
Rna biology
DOI: https://doi.org/10.1080/15476286.2016.1247148
Research output: Contribution to Journal › Article (Published) -
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation
(16 pages)
In:
RNA, vol. 22, pp. 1411-1426
DOI: https://doi.org/10.1261/rna.057158.116
Research output: Contribution to Journal › Article (Published)