Dr James Prendergast
Group Leader
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Background
James completed his PhD in bioinformatics and statistical genetics in 2007 from the University of Edinburgh, and following positions at the European Bioinformatics Institute and University College Dublin returned to Edinburgh to work first at the MRC Human genetics unit before joining the Roslin in 2013. James’s group is focused on understanding mammalian gene regulation, genome evolution and human and animal disease genetics.
Current research interests
Mammalian gene regulation and disease genetics.-
Profiling the immune epigenome across global cattle breeds
(31 pages)
In:
Genome Biology, vol. 24, pp. 1-31
DOI: https://doi.org/10.1186/s13059-023-02964-3
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Rare genetic variants underlie outlying levels of DNA methylation and gene-expression
(10 pages)
In:
Human Molecular Genetics, pp. 1-10
DOI: https://doi.org/10.1093/hmg/ddad028
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Reply to: Genotype by sex interactions in ankylosing spondylitis
(2 pages)
In:
Nature Genetics, vol. 55, pp. 17-18
DOI: https://doi.org/10.1038/s41588-022-01251-4
Research output: Contribution to Journal › Article (Published) -
Using machine learning to detect the differential usage of novel gene isoforms
In:
BMC Bioinformatics, vol. 23
DOI: https://doi.org/10.1186/s12859-022-04576-3
Research output: Contribution to Journal › Article (Published) -
Longitudinal transcriptome analysis of cattle infected with Theileria parva
In:
International Journal For Parasitology, vol. 52, pp. 799-813
DOI: https://doi.org/10.1016/j.ijpara.2022.07.006
Research output: Contribution to Journal › Article (Published) -
Optical mapping compendium of structural variants across global cattle breeds
(8 pages)
In:
Scientific Data, vol. 9, pp. 1-8
DOI: https://doi.org/10.1038/s41597-022-01684-w
Research output: Contribution to Journal › Article (Published) -
The conservation of human functional variants and their effects across livestock species
(13 pages)
In:
Communications biology, vol. 5, pp. 1-13
DOI: https://doi.org/10.1038/s42003-022-03961-1
Research output: Contribution to Journal › Article (Published) -
Assessment of genotyping array performance for genome-wide association studies and imputation in African cattle
In:
Genetics Selection Evolution, vol. 54, pp. 1-23
DOI: https://doi.org/10.1186/s12711-022-00751-5
Research output: Contribution to Journal › Article (Published) -
Next generation sequencing of transcribed genes in ruminant γδ T cell populations
(14 pages)
In:
Molecular Immunology, vol. 149, pp. 129-142
DOI: https://doi.org/10.1016/j.molimm.2022.06.009
Research output: Contribution to Journal › Article (Published) -
Graphia: A platform for the graph-based visualisation and analysis of high dimensional data
In:
PLoS Computational Biology, vol. 18
DOI: https://doi.org/10.1371/journal.pcbi.1010310
Research output: Contribution to Journal › Article (Published)