Dr James Prendergast
Group Leader
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Background
James completed his PhD in bioinformatics and statistical genetics in 2007 from the University of Edinburgh, and following positions at the European Bioinformatics Institute and University College Dublin returned to Edinburgh to work first at the MRC Human genetics unit before joining the Roslin in 2013. James’s group is focused on understanding mammalian gene regulation, genome evolution and human and animal disease genetics.
Current research interests
Mammalian gene regulation and disease genetics.-
Rare missense functional variants at COL4A1 and COL4A2 in sporadic intracerebral Hhmorrhage
In:
Neurology
DOI: https://doi.org/10.1212/WNL.0000000000012227
Research output: Contribution to Journal › Article (Accepted/In press) -
Corrigendum to "Inverted CD4 +/CD8+T cell ratio in Boran (Bos indicus) cattle" [Vet. Immunol. Immunopathol. 230 110126]
In:
Veterinary Immunology and Immunopathology
DOI: https://doi.org/10.1016/j.vetimm.2021.110219
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Whole-genome sequence data suggests environmental adaptation of Ethiopian sheep populations
In:
Genome Biology and Evolution
DOI: https://doi.org/10.1093/gbe/evab014
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Investigating the origin and authenticity of Victoria Cross Medals using X-ray fluorescence spectrometry
In:
Scientific Reports
DOI: https://doi.org/10.1038/s41598-020-76783-y
Research output: Contribution to Journal › Article (Published) -
Inverted CD4+/CD8+ T cell ratio in Boran (Bos indicus) cattle
In:
Veterinary Immunology and Immunopathology
DOI: https://doi.org/10.1016/j.vetimm.2020.110126
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication
(13 pages)
In:
Nature Communications, vol. 11
DOI: https://doi.org/10.1038/s41467-020-18550-1
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophages.
In:
Frontiers in Cell and Developmental Biology
DOI: https://doi.org//10.3389/fcell.2020.00661
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Loss‐of‐function mutations in the ALPL gene presenting with adult onset osteoporosis and low serum concentrations of total alkaline phosphatase
(4 pages)
In:
Journal of Bone and Mineral Research, vol. 35, pp. 657-661
DOI: https://doi.org/10.1002/jbmr.3928
Research output: Contribution to Journal › Article (Published) -
Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalization
In:
Nature Communications, vol. 11
DOI: https://doi.org/10.1038/s41467-019-13762-6
Research output: Contribution to Journal › Article (Published) -
Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions
(30 pages)
In:
PLoS Genetics, vol. 15, pp. 1-29
DOI: https://doi.org/10.1371/journal.pgen.1008480
Research output: Contribution to Journal › Article (E-pub ahead of print)