Dr James Prendergast
Group Leader
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Background
James completed his PhD in bioinformatics and statistical genetics in 2007 from the University of Edinburgh, and following positions at the European Bioinformatics Institute and University College Dublin returned to Edinburgh to work first at the MRC Human genetics unit before joining the Roslin in 2013. James’s group is focused on understanding mammalian gene regulation, genome evolution and human and animal disease genetics.
Current research interests
Mammalian gene regulation and disease genetics.-
A locus conferring tolerance to Theileria infection in African cattle
In:
PLoS Genetics
Research output: Contribution to Journal › Article (Accepted/In press) -
Using machine learning to detect the differential usage of novel gene isoforms
In:
BMC Bioinformatics, vol. 23
DOI: https://doi.org/10.1186/s12859-022-04576-3
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Inherited tolerance in cattle to the apicomplexan protozoan Theileria parva is associated with decreased proliferation of parasite-infected lymphocytes
In:
Frontiers in Cellular and Infection Microbiology
DOI: https://doi.org/10.3389/fcimb.2021.751671
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Clinical evaluation of Corridor disease in Bos indicus (Boran) cattle naturally infected with buffalo-derived Theileria parva
In:
Frontiers in Veterinary Science, vol. 8
DOI: https://doi.org/10.3389/fvets.2021.731238
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Sex differences in genetic architecture in the UK Biobank
(7 pages)
In:
Nature Genetics, vol. 53, pp. 1283-1289
DOI: https://doi.org/10.1038/s41588-021-00912-0
Research output: Contribution to Journal › Article (Published) -
Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability
In:
PLoS ONE, vol. 16
DOI: https://doi.org/10.1371/journal.pone.0256181
Research output: Contribution to Journal › Article (E-pub ahead of print) -
nf-LO: A scalable, containerised workflow for genome-to-genome lift over
In:
Genome Biology and Evolution
DOI: https://doi.org/10.1093/gbe/evab183
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Rare missense functional variants at COL4A1 and COL4A2 in sporadic intracerebral Hhmorrhage
In:
Neurology
DOI: https://doi.org/10.1212/WNL.0000000000012227
Research output: Contribution to Journal › Article (Published) -
Corrigendum: Inverted CD4 +/CD8+T cell ratio in Boran (Bos indicus) cattle"
In:
Veterinary Immunology and Immunopathology
DOI: https://doi.org/10.1016/j.vetimm.2021.110219
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Whole-genome sequence data suggests environmental adaptation of Ethiopian sheep populations
In:
Genome Biology and Evolution
DOI: https://doi.org/10.1093/gbe/evab014
Research output: Contribution to Journal › Article (E-pub ahead of print)