Ian Simpson

Director CDT in Biomedical Artificial Intelligence & Reader in Biological Informatics

Institute for Adaptive & Neural Computation
School of Informatics

School of Informatics

Street: School of Informatics
The University of Edinburgh
10 Crichton Street
City: Edinburgh
Post code: EH8 9AB

Teaching & PhD supervision

Postgraduate teaching

Bioinformatics 1 - (INFR11160)

Bioinformatics 2 - (INFR11005)

Open to PhD supervision enquiries?

Yes

Areas of interest for supervision

UG4, MInf, MSc & PhD students

Current PhD students supervised

Current PhD Students

Alba Crespi
Magdalena Navarro
Aidan Marnane
Antoine Lain

Past PhD students supervised

Completed PhD Students

Xin He (2017)
Maciej Pajak (2018)
Emilia Wysocka (2019)
Samuel Heron (2019)

Developing novel computational, statistical and machine learning methodologies to understand biological systems. In particular the development and function of the brain in relation to neurological diseases.

Current research interests

- Analysis of High-Throughput Data from the Brain - Graph-Based Approaches for the Analysis of Biological Data - Molecular Phylogenetics - Molecular Modelling of Brain Disease

Knowledge exchange

Member of the RSE Young Academy of Scotland (https://www.youngacademyofscotland.org.uk)
STEM Ambassador

Affiliated research centres

Publications

A unified resource and configurable model of the synapse proteome and its role in disease 11 May 2021 In: Scientific Reports, vol. 11
DOI: https://doi.org/10.1038/s41598-021-88945-7
Research output: Contribution to Journal › Article (E-pub ahead of print)
SFARI Genes and where to find them; classification modelling to identify genes associated with Autism Spectrum Disorder from RNA-seq data 1 Feb 2021
DOI: https://doi.org/10.1101/2021.01.29.428754
Research output: › Other contribution (Published)
A configurable model of the synaptic proteome reveals the molecular mechanisms of disease co-morbidity 27 Oct 2020
DOI: https://doi.org/10.1101/2020.10.27.356899
Research output: › Working paper (Published)
MicroRNA-34a Acutely Regulates Synaptic Efficacy in the Adult Dentate Gyrus In Vivo (14 pages) 31 Mar 2020 In: Molecular Neurobiology, vol. 57, pp. 1432–1445
DOI: https://doi.org/10.1007/s12035-019-01816-1
Research output: Contribution to Journal › Article (Published)
Mixed-species RNA-seq for elucidating non-cell-autonomous control of gene transcription (26 pages) 24 Sep 2018 In: Nature Protocols
DOI: https://doi.org/10.1038/s41596-018-0029-2
Research output: Contribution to Journal › Article (Published)
Circadian protein regulation in the green lineage I. A phospho-dawn anticipates light onset before proteins peak in daytime (35 pages) 4 Apr 2018
DOI: https://doi.org/10.1101/287862
Research output: › Working paper (Published)
Erratum: Author Correction: Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism (Nature communications (2017) 8 (15132)) (1 page) 6 Feb 2018 In: Nature Communications, vol. 9
DOI: https://doi.org/10.1038/ncomms16176
Research output: Contribution to Journal › Comment/debate (Published)
Analysis of proteins in computational models of synaptic plasticity (53 pages) 28 Jan 2018
DOI: https://doi.org/10.1101/254094
Research output: › Working paper (Published)
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism (17 pages) 2 May 2017 In: Nature Communications, vol. 8, pp. 1-17
DOI: https://doi.org/10.1038/ncomms15132
Research output: Contribution to Journal › Article (Published)
Community detection identifies a subnetwork of the synaptic proteome associated with differences in educational attainment 22 Mar 2017
Research output: Contribution to Conference › Poster (Published)

View all 40 publications on Research Explorer

This article was published on 14 Oct, 2021