Ian Simpson

Director CDT in Biomedical Artificial Intelligence & Reader in Biological Informatics

Institute for Adaptive & Neural Computation
School of Informatics

School of Informatics

Street: School of Informatics
The University of Edinburgh
10 Crichton Street
City: Edinburgh
Post code: EH8 9AB

Teaching & PhD supervision

Postgraduate teaching

Bioinformatics 1 - (INFR11160)

Bioinformatics 2 - (INFR11005)

Open to PhD supervision enquiries?

Yes

Areas of interest for supervision

UG4, MInf, MSc & PhD students

Current PhD students supervised

Current PhD Students

Alba Crespi
Magdalena Navarro
Aidan Marnane
Antoine Lain
Barry Ryan

Current M.D. Students

Jamie Campbell
Michael Yates

Past PhD students supervised

Completed PhD Students

Xin He (2017)
Maciej Pajak (2018)
Emilia Wysocka (2019)
Samuel Heron (2019)

Developing novel computational, statistical and machine learning methodologies to understand biological systems. In particular the development and function of the brain in relation to neurological diseases.

Current research interests

- Analysis of High-Throughput Data from the Brain - Graph-Based Approaches for the Analysis of Biological Data - Molecular Phylogenetics - Molecular Modelling of Brain Disease

Knowledge exchange

Member of the RSE Young Academy of Scotland (https://www.youngacademyofscotland.org.uk)
Fellow of the Alan Turing Institute (2021-)
Member of the BBSRC Pool of Experts (2021-)
STEM Ambassador

Affiliated research centres

Publications

SFARI genes and where to find them; modelling Autism Spectrum Disorder specific gene expression dysregulation with RNA-seq data (15 pages) 16 Jun 2022 In: Scientific Reports, vol. 12
DOI: https://doi.org/10.1038/s41598-022-14077-1
Research output: Contribution to Journal › Article (Published)
Creation and evaluation of full-text literature-derived, feature-weighted disease models of genetically determined developmental disorders (10 pages) 7 Jun 2022 In: Database: The Journal of Biological Databases and Curation, vol. 2022
DOI: https://doi.org/10.1093/database/baac038
Research output: Contribution to Journal › Article (Published)
Comparison of rule- and ordinary differential equation-based dynamic model of DARPP-32 signalling network (24 pages) 27 Mar 2022
DOI: https://doi.org/10.1101/2022.03.26.485918
Research output: › Preprint (Published)
Creation and evaluation of full-text literature-derived, feature-weighted disease models of genetically determined developmental disorders 5 Nov 2021
DOI: https://doi.org/10.1101/2021.11.04.21265878
Research output: › Other contribution (Published)
Presence of DNA from Chlamydia-like organisms in the nasal cavities of grey seal pups (Halichoerus grypus) and three different substrates present in a breeding colony 13 Oct 2021 In: BMC Veterinary Research, vol. 17, pp. 328
DOI: https://doi.org/10.1186/s12917-021-03032-3
Research output: Contribution to Journal › Article (Published)
A unified resource and configurable model of the synapse proteome and its role in disease 11 May 2021 In: Scientific Reports, vol. 11
DOI: https://doi.org/10.1038/s41598-021-88945-7
Research output: Contribution to Journal › Article (E-pub ahead of print)
SFARI Genes and where to find them; classification modelling to identify genes associated with Autism Spectrum Disorder from RNA-seq data 1 Feb 2021
DOI: https://doi.org/10.1101/2021.01.29.428754
Research output: › Other contribution (Published)
A configurable model of the synaptic proteome reveals the molecular mechanisms of disease co-morbidity 27 Oct 2020
DOI: https://doi.org/10.1101/2020.10.27.356899
Research output: › Working paper (Published)
MicroRNA-34a Acutely Regulates Synaptic Efficacy in the Adult Dentate Gyrus In Vivo (14 pages) 31 Mar 2020 In: Molecular Neurobiology, vol. 57, pp. 1432–1445
DOI: https://doi.org/10.1007/s12035-019-01816-1
Research output: Contribution to Journal › Article (Published)
Mixed-species RNA-seq for elucidating non-cell-autonomous control of gene transcription (26 pages) 24 Sep 2018 In: Nature Protocols
DOI: https://doi.org/10.1038/s41596-018-0029-2
Research output: Contribution to Journal › Article (Published)

View all 45 publications on Research Explorer

This article was published on 3 Aug, 2022