Evropi Theodoratou
Professor of Cancer Epidemiology and Global Health
- Usher Institute
- College of Medicine and Veterinary Medicine
Contact details
Address
- Street
-
Usher Institute – The University of Edinburgh
Old Medical School
Teviot Place - City
- Edinburgh
- Post code
- EH8 9AG
Background
Current roles
- Professor of Cancer Epidemiology and Global Health, University of Edinburgh 2019-
- CRUK Career Development Fellow 2017-
- Co-lead UNCOVER (Usher Network for COVID-19 Evidence Reviews) 2021-
Previous roles
- Reader, University of Edinburgh 2017-2019
- Senior Lecturer/ Chancellor’s Fellow, University of Edinburgh 2014-2017
- Post-doctoral research fellow, University of Edinburgh 2012-2014
- CRUK Population research post-doctoral fellow, University of Edinburgh 2009-2012
Qualifications
- BSc in Biology, Aristotle University of Thessalonica, Greece, 2003
- MSc in Medical Biology, University of Linkoping, Sweden, 2004
- PhD in Cancer Epidemiology, University of Edinburgh, UK, 2009
Responsibilities & affiliations
- Fellow by distinction of the Faculty of Public Health (2018)
- Chief Scientist Office, Health Improvement, Protection and Services Research Committee, 2019-
- Cancer Research UK, Prevention and Population Research Committee, 2020-
- Affiliate scientist, Stanford University (USA), Stanford School of Medicine, METRICS (Meta-research Innovation Centre at Stanford), 2018-
Undergraduate teaching
Programme Director of BMedSci (Epidemiology) intercalated Honours programme that can be taken by medical students in year 3.
Postgraduate teaching
Course Director of “Intermediate Epidemiology”, an elective for the University of Edinburgh’s Master of Public Health (MPH) online programme.
Professor Theodoratou currently supervises MPH students, MSc students, undergraduate students, PhD students (currently 5) and MRes students.
Research summary
Professor Theodoratou’s primary research interest is in colorectal cancer epidemiology (see www.ed.ac.uk/cancer-centre/research/evropi-theodoratou for more information). This research focuses on projects in genetic, molecular and clinical epidemiology. She currently holds six personal awards as PI or co-investigator.
Her CRUK Career Development Fellowship (£1.5m over 6 years) aims to improve and refine bowel cancer identification for those with bowel symptoms, using population screening and diagnostic pathways. The ultimate target is to reduce the overall death rate by improving survival outcomes and patient journeys (see www.ed.ac.uk/usher/lothian-bowel-symptoms-study for more information).
Another active research area is the application of the phenome-wide association study methodology (PheWAS) to investigate the associations between certain genetic variations or biomarker levels and multiple clinical outcomes.
Professor Theodoratou is also interested in developing and applying new research methods in relation to empirical research and evidence-based medicine. She co-leads UNCOVER, a network of population health researchers and information specialists who are committed to responding quickly to requests from policymakers for evidence reviews in relation to the COVID-19 pandemic. See www.ed.ac.uk/usher/uncover for more information.
Project activity
-
Letter: disentangling the role of redox-active compounds in the development of inflammatory bowel diseases – moving towards causal associations - authors' reply
In:
Alimentary Pharmacology and Therapeutics
Research output: Contribution to Journal › Letter (Accepted/In press) -
The contribution of genetic risk and lifestyle factors in the development of adult-onset inflammatory bowel disease: a prospective cohort study
In:
The American Journal of Gastroenterology, vol. 118, pp. 511-522
DOI: https://doi.org/10.14309/ajg.0000000000002180
Research output: Contribution to Journal › Article (Published) -
Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank
In:
The American Journal of Clinical Nutrition (AJCN), vol. 117, pp. 564-575
DOI: https://doi.org/10.1016/j.ajcnut.2023.01.005
Research output: Contribution to Journal › Article (Published) -
Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases
In:
EBioMedicine, vol. 89
DOI: https://doi.org/10.1016/j.ebiom.2023.104488
Research output: Contribution to Journal › Article (Published) -
N6-methylandenosine-related gene expression signatures for predicting the overall survival and immune responses of patients with colorectal cancer
In:
Frontiers in genetics
Research output: Contribution to Journal › Article (Accepted/In press) -
Double faecal immunochemical testing in patients with symptoms suspicious of colorectal cancer
In:
British Journal of Surgery
DOI: https://doi.org/10.1093/bjs/znad016
Research output: Contribution to Journal › Article (Published) -
Antioxidants, Minerals, and Vitamins in Relation to Crohn’s disease and Ulcerative Colitis: A Mendelian Randomization Study
In:
Alimentary Pharmacology and Therapeutics, vol. 57, pp. 399-408
DOI: https://doi.org/10.1111/apt.17392
Research output: Contribution to Journal › Article (Published) -
Comprehensive Investigation on Associations between Dietary Intake and Blood Levels of Fatty Acids and Colorectal Cancer Risk
(13 pages)
In:
Nutrients, vol. 15
DOI: https://doi.org/10.3390/nu15030730
Research output: Contribution to Journal › Article (Published) -
Risk of serious COVID-19 outcomes among adults and children with moderate-to-severe asthma: a systematic review and meta-analysis
In:
European Respiratory Review, vol. 31
DOI: https://doi.org/10.1183/16000617.0066-2022
Research output: Contribution to Journal › Review article (Published) -
Bi-directional Mendelian randomization analysis provides evidence for the causal involvement of dysregulation of CXCL9, CCL11 and CASP8 in the pathogenesis of ulcerative colitis
In:
Journal of Crohn's and Colitis
DOI: https://doi.org/10.1093/ecco-jcc/jjac191
Research output: Contribution to Journal › Article (E-pub ahead of print)