Evropi Theodoratou
Professor of Cancer Epidemiology and Global Health

- Usher Institute
- College of Medicine and Veterinary Medicine
Contact details
Address
- Street
-
Usher Institute – The University of Edinburgh
Old Medical School
Teviot Place - City
- Edinburgh
- Post code
- EH8 9AG
Background
Current roles
- Professor of Cancer Epidemiology and Global Health, University of Edinburgh 2019-
- CRUK Career Development Fellow 2017-
- Co-lead UNCOVER (Usher Network for COVID-19 Evidence Reviews) 2021-
Previous roles
- Reader, University of Edinburgh 2017-2019
- Senior Lecturer/ Chancellor’s Fellow, University of Edinburgh 2014-2017
- Post-doctoral research fellow, University of Edinburgh 2012-2014
- CRUK Population research post-doctoral fellow, University of Edinburgh 2009-2012
Qualifications
- BSc in Biology, Aristotle University of Thessalonica, Greece, 2003
- MSc in Medical Biology, University of Linkoping, Sweden, 2004
- PhD in Cancer Epidemiology, University of Edinburgh, UK, 2009
Responsibilities & affiliations
- Fellow by distinction of the Faculty of Public Health (2018)
- Chief Scientist Office, Health Improvement, Protection and Services Research Committee, 2019-
- Cancer Research UK, Prevention and Population Research Committee, 2020-
- Affiliate scientist, Stanford University (USA), Stanford School of Medicine, METRICS (Meta-research Innovation Centre at Stanford), 2018-
Undergraduate teaching
Programme Director of BMedSci (Epidemiology) intercalated Honours programme that can be taken by medical students in year 3.
Postgraduate teaching
Course Director of “Intermediate Epidemiology”, an elective for the University of Edinburgh’s Master of Public Health (MPH) online programme.
Professor Theodoratou currently supervises MPH students, MSc students, undergraduate students, PhD students (currently 5) and MRes students.
Research summary
Professor Theodoratou’s primary research interest is in colorectal cancer epidemiology (see www.ed.ac.uk/cancer-centre/research/evropi-theodoratou for more information). This research focuses on projects in genetic, molecular and clinical epidemiology. She currently holds six personal awards as PI or co-investigator.
Her CRUK Career Development Fellowship (£1.5m over 6 years) aims to improve and refine bowel cancer identification for those with bowel symptoms, using population screening and diagnostic pathways. The ultimate target is to reduce the overall death rate by improving survival outcomes and patient journeys (see www.ed.ac.uk/usher/lothian-bowel-symptoms-study for more information).
Another active research area is the application of the phenome-wide association study methodology (PheWAS) to investigate the associations between certain genetic variations or biomarker levels and multiple clinical outcomes.
Professor Theodoratou is also interested in developing and applying new research methods in relation to empirical research and evidence-based medicine. She co-leads UNCOVER, a network of population health researchers and information specialists who are committed to responding quickly to requests from policymakers for evidence reviews in relation to the COVID-19 pandemic. See www.ed.ac.uk/usher/uncover for more information.
Project activity
-
Field synopsis of environmental and genetic risk factors of sporadic early-onset colorectal cancer and advanced adenoma
In:
Cancer Epidemiology, Biomarkers & Prevention
DOI: https://doi.org/10.1158/1055-9965.EPI-22-1316
Research output: Contribution to Journal › Article (Published) -
Letter: disentangling the role of redox-active compounds in the development of inflammatory bowel diseases – moving towards causal associations - authors' reply
In:
Alimentary Pharmacology and Therapeutics, vol. 57, pp. 1048-1049
DOI: https://doi.org/10.1111/apt.17468
Research output: Contribution to Journal › Letter (Published) -
Editorial: in search of environmental risk factors of Crohn's disease and ulcerative colitis with mendelian randomisation-authors' reply
(2 pages)
In:
Alimentary Pharmacology and Therapeutics, vol. 57, pp. 1034-1035
DOI: https://doi.org/10.1111/apt.17471
Research output: Contribution to Journal › Article (Published) -
Defining gene–lifestyle interactions in inflammatory bowel disease: progress towards understanding disease pathogenesis
In:
Gut
DOI: https://doi.org/10.1136/gutjnl-2023-329875
Research output: Contribution to Journal › Letter (E-pub ahead of print) -
Exploring the complex relationship between gut microbiota and risk of colorectal neoplasia using bidirectional Mendelian Randomization analysis
In:
Cancer Epidemiology, Biomarkers & Prevention
DOI: https://doi.org/10.1158/1055-9965.EPI-22-0724
Research output: Contribution to Journal › Article (Published) -
Double faecal immunochemical testing in patients with symptoms suspicious of colorectal cancer
In:
British Journal of Surgery, vol. 110, pp. 471-480
DOI: https://doi.org/10.1093/bjs/znad016
Research output: Contribution to Journal › Article (Published) -
A feasibility study of perioperative vitamin D supplementation in patients undergoing colorectal cancer resection
(8 pages)
In:
Frontiers in Nutrition, vol. 10, pp. 1106431
DOI: https://doi.org/10.3389/fnut.2023.1106431
Research output: Contribution to Journal › Article (Published) -
Cross-cancer pleiotropic analysis identifies three novel genetic risk variants for colorectal cancer
In:
Human Molecular Genetics
DOI: https://doi.org/10.1093/hmg/ddad044
Research output: Contribution to Journal › Article (E-pub ahead of print) -
N6-methylandenosine-related gene expression signatures for predicting the overall survival and immune responses of patients with colorectal cancer
In:
Frontiers in genetics, vol. 14, pp. 885930
DOI: https://doi.org/10.3389/fgene.2023.885930
Research output: Contribution to Journal › Article (Published) -
The contribution of genetic risk and lifestyle factors in the development of adult-onset inflammatory bowel disease: a prospective cohort study
In:
The American Journal of Gastroenterology, vol. 118, pp. 511-522
DOI: https://doi.org/10.14309/ajg.0000000000002180
Research output: Contribution to Journal › Article (Published)