Dr Emily Clark
Chancellors Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
My undergraduate degree was in Animal Biology at the University of St Andrews where I stayed to do a masters in quantitative biology before moving to the University of Dundee and James Hutton Institute for my PhD in molecular phylogenetics. I then continued similar phylogenetics work at the Royal Veterinary College as a post doc, this time in the poultry parasite Eimeria. After 3 years at the RVC I moved to become a Research Fellow in livestock functional genomics and transcriptomics at The Roslin Institute where I led the BBSRC funded Sheep Gene Expression Atlas Project. The main focus of the project was to analyse gene expression across a wide range of different tissues and cell types from multiple developmental stages from sheep using RNA-Sequencing. The Sheep Gene Expression Atlas is a key contribution to the international Functional Annotation of Animal Genomes (FAANG) initiative. I have recently been appointed a Chancellor’s Fellow at the University of Edinburgh to continue work on functional genomics in livestock at the Roslin Institute and within the Centre for Tropical Livestock Genetics and Health.
Qualifications
2006 Doctor of Philosophy (PhD), University of Dundee Molecular characterisation of the bacteria associated with the Cabbage Aphid
2005 Master of Research, University of St Andrews
2001 Bachelor of Science (Honours), University of St Andrews
Research summary
My main research interests focus on transcriptomics and genomics in livestock in both production animals and indigenous African breeds. I am particularly interested in functional annotation and the transcriptional control of complex traits.
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Breeding in an Era of Genome Editing
Research output: › Chapter (peer-reviewed) (Accepted/In press) -
Profiling of open chromatin in developing pig (Sus scrofa) muscle to identify regulatory regions
In:
G3: Genes | Genomes | Genetics
Research output: Contribution to Journal › Article (Accepted/In press) -
VarGoats project: a dataset of 1159 whole-genome sequences to dissect Capra hircus global diversity
In:
Genetics Selection Evolution, vol. 53, pp. 86
DOI: https://doi.org/10.1186/s12711-021-00659-6
Research output: Contribution to Journal › Article (Published) -
An improved ovine reference genome assembly to facilitate in depth functional annotation of the sheep genome
In:
GigaScience
Research output: Contribution to Journal › Article (Accepted/In press) -
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
In:
Nature Communications, vol. 12
DOI: https://doi.org/10.1038/s41467-021-23143-7
Research output: Contribution to Journal › Article (Published) -
Detection of copy number variants in African goats using whole genome sequence data
In:
BMC Genomics, vol. 22, pp. 398
DOI: https://doi.org/10.1186/s12864-021-07703-1
Research output: Contribution to Journal › Article (Published) -
Use of quantitative real-time PCR to determine the local inflammatory response in the intestinal mucosa and muscularis externa of horses undergoing small intestinal resection
In:
Equine Veterinary Journal
DOI: https://doi.org/10.1111/evj.13429
Research output: Contribution to Journal › Article (Published) -
Whole-genome sequence data suggests environmental adaptation of Ethiopian sheep populations
In:
Genome Biology and Evolution
DOI: https://doi.org/10.1093/gbe/evab014
Research output: Contribution to Journal › Article (E-pub ahead of print) -
KLB dysregulation mediates disrupted muscle development in intrauterine growth restriction
In:
Journal of Physiology
Research output: Contribution to Journal › Article (Accepted/In press) -
From FAANG to Fork: Application of Highly Annotated Genomes to Improve Farmed Animal Production
In:
Genome Biology
DOI: https://doi.org/10.1186/s13059-020-02197-8
Research output: Contribution to Journal › Article (Published)