Dr Emily Clark
Chancellors Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
My undergraduate degree was in Animal Biology at the University of St Andrews where I stayed to do a masters in quantitative biology before moving to the University of Dundee and James Hutton Institute for my PhD in molecular phylogenetics. I then continued similar phylogenetics work at the Royal Veterinary College as a post doc, this time in the poultry parasite Eimeria. After 3 years at the RVC I moved to become a Research Fellow in livestock functional genomics and transcriptomics at The Roslin Institute where I led the BBSRC funded Sheep Gene Expression Atlas Project. The main focus of the project was to analyse gene expression across a wide range of different tissues and cell types from multiple developmental stages from sheep using RNA-Sequencing. The Sheep Gene Expression Atlas is a key contribution to the international Functional Annotation of Animal Genomes (FAANG) initiative. I have recently been appointed a Chancellor’s Fellow at the University of Edinburgh to continue work on functional genomics in livestock at the Roslin Institute and within the Centre for Tropical Livestock Genetics and Health.
Qualifications
2006 Doctor of Philosophy (PhD), University of Dundee Molecular characterisation of the bacteria associated with the Cabbage Aphid
2005 Master of Research, University of St Andrews
2001 Bachelor of Science (Honours), University of St Andrews
Research summary
My main research interests focus on transcriptomics and genomics in livestock in both production animals and indigenous African breeds. I am particularly interested in functional annotation and the transcriptional control of complex traits.
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Improving the annotation of the cattle genome by annotating transcription start sites in a diverse set of tissues and populations using CAGE sequencing
(38 pages)
In:
G3: Genes | Genomes | Genetics, pp. 1-38
DOI: https://doi.org/10.1093/g3journal/jkad108
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A versatile nuclei extraction protocol for single nucleus sequencing in non-model species – optimization in various Atlantic salmon tissues
In:
PLoS ONE
Research output: Contribution to Journal › Article (Accepted/In press) -
Phenotypic and genetic characterisation of disease subtypes of equine recurrent exertional rhabdomyolysis
(2 pages)
DOI: https://doi.org/10.1016/j.anscip.2023.01.454
Research output: Contribution to Conference › Conference contribution (Published) -
Natural adaptation and human selection of northeast African sheep genomes
In:
Genomics, vol. 114
DOI: https://doi.org/10.1016/j.ygeno.2022.110448
Research output: Contribution to Journal › Article (Published) -
Geographical contrasts of Y-chromosomal haplogroups from wild and domestic goats reveal ancient migrations and recent introgressions
(17 pages)
In:
Molecular Ecology, vol. 31, pp. 4364-4380
DOI: https://doi.org/10.1111/mec.16579
Research output: Contribution to Journal › Article (Published) -
Correction to: Expression of mitochondrial protein genes encoded by nuclear and mitochondrial genomes correlate with energy metabolism in dairy cattle
In:
BMC Genomics, vol. 23
DOI: https://doi.org/10.1186/s12864-022-08404-z
Research output: Contribution to Journal › Comment/debate (Published) -
Breeding in an Era of Genome Editing
DOI: https://doi.org/10.1007/978-1-4939-2493-6_1122-1
Research output: › Chapter (peer-reviewed) (E-pub ahead of print) -
KLB dysregulation mediates disrupted muscle development in intrauterine growth restriction
In:
The Journal of Physiology, vol. 600, pp. 1771-1790
DOI: https://doi.org/10.1113/JP281647
Research output: Contribution to Journal › Article (Published) -
An improved ovine reference genome assembly to facilitate in depth functional annotation of the sheep genome
In:
GigaScience, vol. 11
DOI: https://doi.org/10.1093/gigascience/giab096
Research output: Contribution to Journal › Article (Published) -
Profiling of open chromatin in developing pig (Sus scrofa) muscle to identify regulatory regions
In:
G3: Genes | Genomes | Genetics
DOI: https://doi.org/10.1093/g3journal/jkab424
Research output: Contribution to Journal › Article (E-pub ahead of print)