Dr Umer Naveed Chaudhry
Postdoctoral Scientist
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
I am a veterinary researcher and molecular parasitologist, focusing on multi-host parasites of global animal and human health importance. I am leading antimicrobial drug resistance projects funded by BBSRC UK, Carnegie trust UK, NSERC Canada, HEC Pakistan. A pivotal component of my work involves the construction of Haemonchus contortus genetic linkage map and XQTL analysis to aid in the identification of anthelmintic resistance loci that might help to improve long-term sustainable helminth control measures. Another key component of the work involves field studies, investigating the relationships between pasture larval contamination, the availability of infective larvae on pasture and the build-up of infection in animals, which has led to the investigation of the emergence and spread of resistance mutations and patterns of drug selection in parasitic nematodes: the sustainable control of parasites. Last few years, I also work on the genetics of trematode parasites including the origins of the Calicophoron daubneyi rumen fluke infection in UK (funded by BBSRC-UK) and the spread of anthelmintic resistance in Fasciola gigantica liver fluke funded by HEC Pakistan. I plan to develop this expertise in the study of antimicrobial resistance in protozoan parasites, building on work that I have undertaken to provide genetic evidence of pyrimethamine resistance in Plasmodium vivax funded by HEC Pakistan. I am interested to use and develop this expertise, working with natural field populations of T. annulata to provide new insights into the broader topic of antimicrobial drug resistance funded by Carnegie trust UK.
Research activities
- Selective sweep and phylogenetic models for the emergence and spread of pyrimethamine resistance mutations in Plasmodium vivax (27th Conference of WAAVP Madison USA)
- Parasitology Research (Journal)
- Veterinary Parasitology: Regional Studies and Reports (Journal)
- Frontiers in Cellular and Infection Microbiology (Journal)
- Archives of Virology (Journal)
- Molecular biology reports (Journal)
- Veterinary Parasitology (Journal)
- Nuffield Research Placement
- Molecular genetics and genomics (Journal)
- Parasitology International (Journal)
- Genomics (Journal)
- Microbial pathogenesis (Journal)
-
A 4 year observation of gastrointestinal nematode egg counts, nemabiomes, and the benzimidazole resistance genotypes of Teladorsagia circumcincta on a Scottish sheep farm.
In:
International Journal For Parasitology
DOI: https://doi.org/10.1016/j.ijpara.2020.10.007
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm
In:
Communications biology
DOI: https://doi.org/10.1038/s42003-020-01377-3
Research output: Contribution to Journal › Article (Published) -
Contrasting population genetics of co-endemic cattle- and buffalo- derived Theileria annulata
In:
Ticks and tick-borne diseases
DOI: https://doi.org/10.1016/j.ttbdis.2020.101595
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Zoonotic and Reverse Zoonotic Events of SARS-CoV-2 and their Impact on Global Health
(35 pages)
In:
Emerging Microbes & Infections, pp. 1-35
DOI: https://doi.org/10.1080/22221751.2020.1827984
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Contrasting patterns of isotype-1 β-tubulin allelic diversity in Haemonchus contortus and Haemonchus placei in the southern USA are consistent with a model of localised emergence of benzimidazole resistance
In:
Veterinary Parasitology, vol. 286, pp. 109240
DOI: https://doi.org/10.1016/j.vetpar.2020.109240
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Foot and mouth disease in a wide range of wild hosts: a potential constraint in disease control efforts worldwide particularly in disease-endemic settings
In:
Acta Tropica
DOI: https://doi.org/10.1016/j.actatropica.2020.105567
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Investigation of a gamasid mite infestation in a UK textile mill caused by Dermanyssus gallinae (DeGeer, 1778) (Mesostigmata: Dermanyssidae) special lineage L1
In:
Parasitology International, pp. 102146
DOI: https://doi.org/10.1016/j.parint.2020.102146
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A novel metabarcoded 18S ribosomal DNA sequencing tool for the detection of Plasmodium species in malaria positive patients.
In:
Infection, Genetics and Evolution
DOI: https://doi.org/10.1016/j.meegid.2020.104305
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Sentinel surveillance of selected veterinary and public health pathogens in camel population originating from Southern Punjab province, Pakistan
In:
Acta Tropica
DOI: https://doi.org/10.1016/j.actatropica.2020.105435
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Diagnostic Methods for Detecting Internal Parasites of Livestock
(19 pages)
In:
Veterinary Clinics of North America: Food Animal Practice, vol. 36, pp. 125-143
DOI: https://doi.org/10.1016/j.cvfa.2019.12.003
Research output: Contribution to Journal › Article (Published) -
Genetic diversity and multiplicity of infection in Fasciola gigantica isolates of Pakistani livestock
In:
Parasitology International, pp. 102071
DOI: https://doi.org/10.1016/j.parint.2020.102071
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Contrasting population genetics of cattle-and buffalo-derived Theileria annulata causing tropical theileriosis
DOI: https://doi.org/10.1101/2020.01.10.902031
Research output: › Working paper (Published)