Dr Tom Moullaali
Address
- Street
-
Centre for Clinical Brain Sciences (CCBS)
Chancellor's Building
49 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4SB
Background
I am a member of the Research to Understand Stroke due to Haemorrhage (RUSH) team. Our research aims to improve the outcome for adults who have diseases that may cause, or have caused, intracranial haemorrhage.
Qualifications
2012 Bachelor of Medicine and Bachelor of Surgery, Newcastle University
2016 Membership of the Royal College of Physicians UK, MRCP (UK)
2017 Advanced life support course (ALS)
2021 PhD, University of Edinburgh
Responsibilities & affiliations
European Stroke Organisation young stroke physician and researchers committee member (2019–2024)
European Stroke Organisation Edinburgh stroke research workshop organising committee member (2019– )
Neurology higher speciality trainee, NHS Lothian (2021– )
Research summary
My research focuses on people who have suffered a stroke due to bleeding in the brain (intracerebral haemorrhage, or ICH).
Past research interests
British Heart Foundation clinical research training fellowship January 2018 - January 2021: is blood pressure variability associated with outcomes after stroke due to intracerebral haemorrhage? Blood pressure in acute stroke collaboration (BASC): meta-analysis of individual participant data from randomised controlled trials testing effects of interventions to lower blood pressure after acute intracerebral haemorrhage.Knowledge exchange
Current UK and US guidelines for the management of blood pressure after acute intracerebral haemorrhage include recommendations based on the findings of meta-analyses I led during my PhD fellowship.
Affiliated research centres
Current project grants
PLatform randomised controlled trial for INTracerebral Haemorrhage (PLINTH): community-based feasibility study (2023-2026) - co-investigator
Past project grants
British Heart Foundation clinical research training fellowship: Does blood pressure variability (BPV) affect outcome after stroke due to intracerebral haemorrhage?
-
Blood Pressure Management After Intracerebral and Subarachnoid Hemorrhage: The Knowns and Known Unknowns
In:
Stroke, vol. 53, pp. 1065-1073
DOI: https://doi.org/10.1161/STROKEAHA.121.036139
Research output: Contribution to Journal › Article (Published) -
J-shape relation of blood pressure reduction and outcome in acute intracerebral hemorrhage: A pooled analysis of INTERACT2 and ATACH-II individual participant data
In:
International Journal of Stroke, pp. 174749302110640
DOI: https://doi.org/10.1177/17474930211064076
Research output: Contribution to Journal › Article (Published) -
Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data
In:
Journal of Neurology, Neurosurgery & Psychiatry, pp. jnnp-2021-327195
DOI: https://doi.org/10.1136/jnnp-2021-327195
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Associations of Early Systolic Blood Pressure Control and Outcome After Thrombolysis-Eligible Acute Ischemic Stroke: Results From the ENCHANTED Study
In:
Stroke
DOI: https://doi.org/10.1161/STROKEAHA.121.034580
Research output: Contribution to Journal › Article (Published) -
Effects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage: Extended Follow-up of the RESTART Randomized Clinical Trial
In:
JAMA Neurology
DOI: https://doi.org/10.1001/jamaneurol.2021.2956
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Risks of recurrent stroke and all serious vascular events after spontaneous intracerebral haemorrhage: pooled analyses of two population-based studies
In:
Lancet Neurology, vol. 20, pp. 437-447
DOI: https://doi.org/10.1016/S1474-4422(21)00075-2
Research output: Contribution to Journal › Article (Published) -
Influence of Including Patients with Premorbid Disability in Acute Stroke Trials: The HeadPoST Experience
In:
Cerebrovascular diseases, pp. 1-10
DOI: https://doi.org/10.1159/000512608
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Prescription of blood pressure lowering treatment after intracerebral haemorrhage: Prospective, population-based cohort study
In:
European Stroke Journal, pp. 239698732097572
DOI: https://doi.org/10.1177/2396987320975724
Research output: Contribution to Journal › Article (Published) -
Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study
In:
International Journal of Stroke, pp. 174749302097428
DOI: https://doi.org/10.1177/1747493020974282
Research output: Contribution to Journal › Article (Published) -
Association between Computed Tomographic Biomarkers of Cerebral Small Vessel Diseases and Long-Term Outcome after Spontaneous Intracerebral Hemorrhage
In:
Annals of Neurology
DOI: https://doi.org/10.1002/ana.25949
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Treatment of intracerebral hemorrhage: From specific interventions to bundles of care
In:
International Journal of Stroke, pp. 174749302096466
DOI: https://doi.org/10.1177/1747493020964663
Research output: Contribution to Journal › Article (Published) -
Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome: Pooled Analysis of 20 000+ Patients
In:
Stroke, vol. 51, pp. 2411-2417
DOI: https://doi.org/10.1161/STROKEAHA.119.028523
Research output: Contribution to Journal › Article (Published) -
The Magnitude of Blood Pressure Reduction Predicts Poor In-Hospital Outcome in Acute Intracerebral Hemorrhage
In:
Neurocritical care
DOI: https://doi.org/10.1007/s12028-020-01016-z
Research output: Contribution to Journal › Article (Published) -
Interaction of Blood Pressure Lowering and Alteplase Dose in Acute Ischemic Stroke: Results of the Enhanced Control of Hypertension and Thrombolysis Stroke Study
In:
Cerebrovascular diseases, pp. 1-10
DOI: https://doi.org/10.1159/000504745
Research output: Contribution to Journal › Article (Published) -
Inspiring New Researchers in Stroke: The ESO Edinburgh Stroke Research Workshop
In:
Stroke
DOI: https://doi.org/10.1161/STROKEAHA.119.026936
Research output: Contribution to Journal › Comment/debate (Published) -
Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a pre-planned pooled analysis of individual participant data from the INTERACT2 and ATACH-II trials
In:
Lancet Neurology
DOI: https://doi.org/10.1016/S1474-4422(19)30196-6
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Lowering blood pressure after acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis using individual patient data from randomised controlled trials participating in the Blood Pressure in Acute Stroke Collaboration (BASC)
In:
BMJ Open, vol. 9
DOI: https://doi.org/10.1136/bmjopen-2019-030121
Research output: Contribution to Journal › Article (E-pub ahead of print) -
I Am, I Am, I Am: Seventeen Brushes With Death, by Maggie O’Farrell
In:
Practical Neurology, pp. practneurol-2019-002310
DOI: https://doi.org/10.1136/practneurol-2019-002310
Research output: Contribution to Journal › Book/Film/Article review (Published) -
Who will benefit more from low-dose alteplase in acute ischemic stroke?
In:
International Journal of Stroke, pp. 174749301985877
DOI: https://doi.org/10.1177/1747493019858775
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Low-dose versus standard-dose alteplase in acute ischemic stroke in Asian stroke registries: an individual patient data pooling study
In:
International Journal of Stroke, pp. 174749301985877
DOI: https://doi.org/10.1177/1747493019858777
Research output: Contribution to Journal › Review article (E-pub ahead of print)