Dr Ruth Morgan
Postdoctoral Researcher
Address
- Street
-
The Royal (Dick) School of Veterinary Studies and The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Background
I undertook my veterinary training at the University of Cambridge graduating in 2006. I spent some years in practice and then went on to specialist training in Equine Internal Medicine at the University of Liverpool before moving to edinburgh to undertake my PhD. Following my PhD I spent some time as a post-doctoral researcher prior to becoming a Wellcome Trust Clinical Career Development Fellow, a 4 year post.
Collaborative Activity
I have an active collaboration with Professor Alex Odermatt at the University of Basel.
Qualifications
MA VetMB CertAVP(EM) DipECEIM PhD MRCVS European Specialist in Equine Internal Medicine
Responsibilities & affiliations
The Dick Vet Equine Practice
Research summary
I am interested in the metabolism of stress hormones by different species (horses, humans and mice) and the impact of metabolism on health and disease. I investigate the role of glucocorticoid metabolites in the excessive activation of glucocorticoid and mineralocorticoid receptors in obesity associated morbidities such as hypertension. I am interested in comparative endocrinology and what we can learn about glucocorticoids and disease from different species.
-
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
In:
Molecular Metabolism
DOI: https://doi.org/10.1016/j.molmet.2021.101225
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Inducing weight loss in native ponies: is straw a viable alternative to hay?: Inducing weight loss in native ponies: is straw a viable alternative to hay?
In:
Veterinary Record
DOI: https://doi.org/10.1136/vr.105793
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Quantitative analysis of 11-dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography triple quadrupole mass spectrometry
In:
Rapid communications in mass spectrometry
DOI: https://doi.org/10.1002/rcm.8610
Research output: Contribution to Journal › Article (Published) -
Adipose tissue dysfunction in obese horses with Equine Metabolic Syndrome
In:
Equine Veterinary Journal
DOI: https://doi.org/10.1111/evj.13097
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Dysregulation of cortisol metabolism in equine pituitary pars intermedia dysfunction
(10 pages)
In:
Endocrinology, vol. 159, pp. 3791–3800
DOI: https://doi.org/10.1210/en.2018-00726
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Equine Obesity: Current Perspectives
In:
UK-Vet Equine, vol. 2
DOI: https://doi.org/10.12968/ukve.2018.2.S2.3
Research output: Contribution to Journal › Review article (Published) -
Assessment of tissue-specific cortisol activity with regard to degeneration of the suspensory ligaments in horses with pituitary pars intermedia dysfunction
(12 pages)
In:
American Journal of Veterinary Research, vol. 79, pp. 199-210
DOI: https://doi.org/10.2460/ajvr.79.2.199
Research output: Contribution to Journal › Article (Published) -
Species-specific regulation of angiogenesis by glucocorticoids reveals contrasting effects on inflammatory and angiogenic pathways
In:
PLoS ONE, vol. 13
DOI: https://doi.org/10.1371/journal.pone.0192746
Research output: Contribution to Journal › Article (Published) -
Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity
In:
Scientific Reports, vol. 7
DOI: https://doi.org/10.1038/s41598-017-10410-1
Research output: Contribution to Journal › Article (Published) -
Vascular Dysfunction in Horses with Endocrinopathic Laminitis
In:
PLoS ONE, vol. 11
DOI: https://doi.org/10.1371/journal.pone.0163815
Research output: Contribution to Journal › Article (Published)