Dr Mark Hughes
Clinical Lecturer & Honorary Specialist Registrar in Neurosurgery

Background
Mark Hughes is a clinical lecturer in neurosurgery and recently completed a Wellcome Trust-funded PhD (via the Edinburgh Clinical Academic Track).
Research summary
The brain is a powerful and efficient biological computer. Mark Hughes’ research explores the interface between neurons and biomaterials, especially silicon. Engineering and interacting with simple networks of neurons in the lab offers a chance to explore how larger networks operate in complex, living organisms.
As well as being relevant to understanding how nervous systems represent and process information, related insights can also inform novel (or hybrid) computational strategies. Moreover, tools to interface with engineered networks are relevant in the fledgling field of neuroprosthetics.
Areas of interest
neuron:silicon interfaces biomaterials neuro-engineering surgical simulation
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Sellar Remodeling after Surgery for Nonfunctioning Pituitary Adenoma: Intercarotid Distance as a Predictor of Recurrence
In:
Journal of Neurological Surgery Part B: Skull Base
DOI: https://doi.org/10.1055/s-0039-1693700
Contribution to journal › Article (Published) -
Chondroitinase ABC for neurological recovery after acute brain injury : systematic review and meta-analyses of preclinical studies
(15 pages)
In:
Brain Injury, pp. 1-15
DOI: https://doi.org/10.1080/02699052.2018.1438665
Contribution to journal › Review article (E-pub ahead of print) -
Cytotoxicity of ultraviolet-C radiation on a heterogeneous population of human glioblastoma multiforme cells: Meta-analysis
In:
Photodiagnosis and Photodynamic Therapy, vol. 24, pp. 158-163
DOI: https://doi.org/10.1016/j.pdpdt.2018.10.003
Contribution to journal › Article (E-pub ahead of print) -
Delayed diffuse cerebellar swelling after resection of medulloblastoma : case report and review of literature
In:
Child's Nervous System
DOI: https://doi.org/10.1007/s00381-017-3496-9
Contribution to journal › Article (E-pub ahead of print) -
Effects of Ultraviolet Radiation on Glioma : Systematic Review
(9 pages)
In:
Journal of cellular biochemistry, vol. 118, no. 11, pp. 4063-4071
DOI: https://doi.org/10.1002/jcb.26061
Contribution to journal › Literature review (Published)