Mr Mark Hughes (BSc (Hons) MBChB MSc PhD FRCS)
Consultant Neurosurgeon and Honorary Clinical Senior Lecturer
- Department of Clinical Neurosciences
- Centre for Clinical Brain Sciences
- Edinburgh translational neurosurgery research group
Contact details
- Email: mhughes4@exseed.ed.ac.uk
Address
- Street
-
Department of Clinical Neurosciences
- City
- Post code
Background
Mark Hughes is consultant neurosurgeon and honorary senior lecturer. He underwent neurosurgical training in London, Edinburgh, New York, and Leeds - and completed a Wellcome Trust-funded PhD en route.
Qualifications
BSc (Hons) Neuroscience
MB ChB
MSc Surgical sciences
MRCS (Ed)
PhD Neuroscience and electrical engineering
FRCS (Neurosurgery)
Undergraduate teaching
SSC students
Postgraduate teaching
MSc students
Research summary
The brain is a powerful and efficient biological computer. Mark Hughes’ doctoral research explored the interface between neurons and biomaterials, especially silicon. Engineering and interacting with simple networks of neurons in the lab offers a chance to explore how larger networks operate in complex, living organisms. As well as being relevant to understanding how nervous systems represent and process information, related insights can also inform novel (or hybrid) computational strategies. Moreover, tools to interface with engineered networks are relevant in the fledgling field of neuroprosthetics.
Current research interests
Current research projects include exploring the use of artificial intelligence to analyse facial images for early detection of acromegaly, and the use of 3D printing to improve patient counselling and surgical planning for skull base operations. In the context of surgical simulation, I have been involved in the research and development of micro-neurosurgical and other minimally invasive surgery platforms. This work has been driven forward via the formation of a spinout company from the University of Edinburgh and has had global impact, with simulators now in use on over 60 different countries and also incorporated into several regional training programs.-
Sellar Remodeling after Surgery for Nonfunctioning Pituitary Adenoma: Intercarotid Distance as a Predictor of Recurrence
In:
Journal of Neurological Surgery Part B: Skull Base
DOI: https://doi.org/10.1055/s-0039-1693700
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Cytotoxicity of ultraviolet-C radiation on a heterogeneous population of human glioblastoma multiforme cells: Meta-analysis
In:
Photodiagnosis and Photodynamic Therapy, vol. 24, pp. 158-163
DOI: https://doi.org/10.1016/j.pdpdt.2018.10.003
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Chondroitinase ABC for neurological recovery after acute brain injury: systematic review and meta-analyses of preclinical studies
(15 pages)
In:
Brain Injury, pp. 1-15
DOI: https://doi.org/10.1080/02699052.2018.1438665
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Effects of Ultraviolet Radiation on Glioma: Systematic Review
(9 pages)
In:
Journal of cellular biochemistry, vol. 118, pp. 4063-4071
DOI: https://doi.org/10.1002/jcb.26061
Research output: Contribution to Journal › Literature review (Published) -
Delayed diffuse cerebellar swelling after resection of medulloblastoma: case report and review of literature
In:
Child's Nervous System
DOI: https://doi.org/10.1007/s00381-017-3496-9
Research output: Contribution to Journal › Article (E-pub ahead of print)