Mr Mark Hughes (BSc (Hons) MBChB MSc PhD FRCS (SN) MFSTEd)

Consultant Neurosurgeon and Honorary Clinical Senior Lecturer

Department of Clinical Neurosciences
Centre for Clinical Brain Sciences
Edinburgh translational neurosurgery research group

Email: mhughes4@exseed.ed.ac.uk

Street: Department of Clinical Neurosciences
City: BioQuarter
Post code

Biography

Background

Mark Hughes is consultant neurosurgeon and honorary senior lecturer. He underwent neurosurgical training in London, Edinburgh, New York, and Leeds - and completed a Wellcome Trust-funded PhD en route. His subspecialist work focuses on pituitary tumours and anterior skull base neurosurgery.

Qualifications

BSc (Hons) Neuroscience

MB ChB

MSc Surgical sciences

MRCS (Ed)

PhD Neuroscience and electrical engineering

FRCS (Neurosurgery)

MFSTEd

Responsibilities & affiliations

Member of the Society of British Neurological Surgeons

Teaching & PhD supervision

Undergraduate teaching

I supervise undergraduate medical student for SSC research projects

Postgraduate teaching

I supervise University of Edinburgh and external MSc students, often via the ESSQ program

Research

Research summary

Mark Hughes’ doctoral research explored the interface between neurons and biomaterials, especially silicon. Engineering and interacting with simple networks of neurons in the lab offers a chance to explore how larger networks operate in complex, living organisms. As well as being relevant to understanding how nervous systems represent and process information, related insights can also inform novel (or hybrid) computational strategies. Moreover, tools to interface with engineered networks are relevant in the fledgling field of neuroprosthetics.

Current research interests

Current research projects include: - Development of an app-based tool to measure and monitor visual field loss due to pituitary and other tumours. - Exploring the use of artificial intelligence to analyse facial images for early detection of acromegaly. - Using 3D printing to improve patient counselling and surgical planning for skull base operations. - Ongoing prospective audit of surgical outcomes for our local endoscopic neurosurgical service.

Knowledge exchange

https://scholar.google.com/citations?user=c8-q2MYAAAAJ&hl=en

In the context of surgical simulation, I have been involved in the research and development of micro-neurosurgical and other minimally invasive surgery platforms. This work has been driven forward via the formation of a spinout company from the University of Edinburgh and has had global impact, with simulators now in use on over 60 different countries and also incorporated into several regional training programs.

Publications

Genomes shed light on the evolution of Begonia , a mega‐diverse genus 2022 In: New Phytologist
DOI: https://doi.org/10.1111/nph.17949
Research output: Contribution to Journal › Article (Published)
The digital Cullen chart: a red colour perimetry aid for visual field examination 17 Dec 2021 In: British Journal of Neurosurgery, pp. 1-5
DOI: https://doi.org/10.1080/02688697.2021.2014782
Research output: Contribution to Journal › Article (E-pub ahead of print)
The Impact of Novel Nontechnical Stressors (Visual and Auditory) on Simulated Laparoscopic Task Performance Among Surgeons and Students 2 Dec 2021 In: Journal of laparoendoscopic & advanced surgical techniques
DOI: https://doi.org/10.1089/lap.2021.0695
Research output: Contribution to Journal › Article (E-pub ahead of print)
Letter to the Editor. A UK perspective on gender diversity in American neurosurgery training programs 2 Jul 2021 In: Journal of Neurosurgery, pp. 1-2
DOI: https://doi.org/10.3171/2021.3.JNS21548
Research output: Contribution to Journal › Letter (E-pub ahead of print)
The gender gap in European neurosurgical conference presentations 1 Mar 2021 In: Neurosurgical focus, vol. 50, pp. E7
DOI: https://doi.org/10.3171/2020.12.FOCUS20885
Research output: Contribution to Journal › Article (E-pub ahead of print)
Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study 25 Nov 2020 In: International Journal of Stroke, pp. 174749302097428
DOI: https://doi.org/10.1177/1747493020974282
Research output: Contribution to Journal › Article (Published)
Using Automated Continuous Instrument Tracking to Benchmark Simulated Laparoscopic Performance and Personalize Training 16 Oct 2020 In: Journal of Surgical Education
DOI: https://doi.org/10.1016/j.jsurg.2020.09.021
Research output: Contribution to Journal › Article (Published)
Sellar Remodeling after Surgery for Nonfunctioning Pituitary Adenoma: Intercarotid Distance as a Predictor of Recurrence 24 Jul 2019 In: Journal of Neurological Surgery Part B: Skull Base
DOI: https://doi.org/10.1055/s-0039-1693700
Research output: Contribution to Journal › Article (E-pub ahead of print)
Cytotoxicity of ultraviolet-C radiation on a heterogeneous population of human glioblastoma multiforme cells: Meta-analysis 9 Oct 2018 In: Photodiagnosis and Photodynamic Therapy, vol. 24, pp. 158-163
DOI: https://doi.org/10.1016/j.pdpdt.2018.10.003
Research output: Contribution to Journal › Article (E-pub ahead of print)
Chondroitinase ABC for neurological recovery after acute brain injury: systematic review and meta-analyses of preclinical studies (15 pages) 14 Feb 2018 In: Brain Injury, pp. 1-15
DOI: https://doi.org/10.1080/02699052.2018.1438665
Research output: Contribution to Journal › Review article (E-pub ahead of print)
Effects of Ultraviolet Radiation on Glioma: Systematic Review (9 pages) Nov 2017 In: Journal of cellular biochemistry, vol. 118, pp. 4063-4071
DOI: https://doi.org/10.1002/jcb.26061
Research output: Contribution to Journal › Literature review (Published)
Delayed diffuse cerebellar swelling after resection of medulloblastoma: case report and review of literature 29 Jun 2017 In: Child's Nervous System
DOI: https://doi.org/10.1007/s00381-017-3496-9
Research output: Contribution to Journal › Article (E-pub ahead of print)
Efficacy, complications and cost of surgical interventions for idiopathic intracranial hypertension: a systematic review of the literature Jan 2017 In: Acta Neurochirurgica, vol. 159
DOI: https://doi.org/10.1007/s00701-016-3010-2
Research output: Contribution to Journal › Review article (Published)
Focused ultrasound as a non-invasive intervention for neurological disease: a review 22 Apr 2016 In: British Journal of Neurosurgery, vol. 30
DOI: https://doi.org/10.3109/02688697.2016.1173189
Research output: Contribution to Journal › Literature review (E-pub ahead of print)
Insinuating electronics in the brain 9 Apr 2016 In: The Surgeon
DOI: https://doi.org/10.1016/j.surge.2016.03.003
Research output: Contribution to Journal › Article (E-pub ahead of print)
Towards a 'siliconeural computer': technological successes and challenges 15 Jul 2015 In: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, vol. 373
DOI: https://doi.org/10.1098/rsta.2014.0217
Research output: Contribution to Journal › Article (Published)
The LEAPTM Gesture Interface Device and Take-Home Laparoscopic Simulators: A Study of Construct and Concurrent Validity 14 Jul 2015 In: Surgical Innovation
DOI: https://doi.org/10.1177/1553350615594734
Research output: Contribution to Journal › Article (Published)
Interventions for idiopathic intracranial hypertension 2015 In: Cochrane Database of Systematic Reviews, vol. 8, pp. CD003434
DOI: https://doi.org/10.1002/14651858.CD003434.pub3
Research output: Contribution to Journal › Article (Published)
Accessible Laparoscopic Instrument Tracking ("InsTrac''): Construct Validity in a Take-Home Box Simulator (6 pages) Aug 2014 In: Journal of laparoendoscopic & advanced surgical techniques, vol. 24, pp. 578-583
DOI: https://doi.org/10.1089/lap.2014.0015
Research output: Contribution to Journal › Article (Published)
Engineering brain-computer interfaces: past, present and future (7 pages) Jun 2014 In: Journal of neurosurgical sciences, vol. 58, pp. 117-123
Research output: Contribution to Journal › Article (Published)

View all 41 publications on Research Explorer

This article was published on 27 Jun, 2022