Dr Mark Bastin
Reader
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Psychotic-like experiences, polygenic risk scores for schizophrenia, and structural properties of the salience, default mode, and central-executive networks in healthy participants from UK Biobank
In:
Translational Psychiatry, vol. 10
DOI: https://doi.org/10.1038/s41398-020-0794-x
Contribution to Journal › Article (Published) -
Age-related changes of Peak width Skeletonized Mean Diffusivity (PSMD) across the adult life span
In:
Frontiers in psychiatry
Contribution to Journal › Article (Accepted/In press) -
Peak width of skeletonized water diffusion MRI in the neonatal brain
In:
Frontiers in Neurology
DOI: https://doi.org/10.3389/fneur.2020.00235
Contribution to Journal › Article (Published) -
The genetic architecture of the human cerebral cortex
In:
Science, vol. 367, pp. eaay6690
DOI: https://doi.org/10.1126/science.aay6690
Contribution to Journal › Article (Published) -
Evolution of white matter damage in amyotrophic lateral sclerosis
In:
Annals of Clinical and Translational Neurology
Contribution to Journal › Article (Accepted/In press)