Dr Mark Bastin
Reader
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Interleukin-8 dysregulation is implicated in brain dysmaturation following preterm birth.
In:
Brain, Behavior, and Immunity
Research output: Contribution to Journal › Article (Published) -
Effect of antenatal magnesium sulphate on MRI biomarkers of white matter development at term equivalent age: The MagNUM Study.
In:
EBioMedicine
DOI: https://doi.org/10.1016/j.ebiom.2020.102957
Research output: Contribution to Journal › Article (Published) -
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22824 adults
In:
Nature Communications
Research output: Contribution to Journal › Article (Accepted/In press) -
Quantitative measurements of enlarged perivascular spaces in the brain are associated with retinal microvascular parameters in older community-dwelling subjects
In:
Cerebral Circulation—Cognition and Behavior
Research output: Contribution to Journal › Article (Accepted/In press) -
Association of common genetic variants with brain microbleeds: A genome-wide association study
In:
Neurology
Research output: Contribution to Journal › Article (Accepted/In press)