Dr Mark Bastin

Reader

Centre for Clinical Brain Sciences
Edinburgh Imaging

Tel: 0131 537 2511
Email: Mark.Bastin@ed.ac.uk

Research

Research summary

My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.

Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.

Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.

Research aims and areas of interest

My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:

Diffusion magnetic resonance imaging and tractography
Magnetization transfer magnetic resonance imaging
Quantitative spin-lattice relaxation (T1) measurement
Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder

Affiliated research centres

Publications

Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort 23 Apr 2021 In: Neurobiology of Aging, pp. 2021.02.02.21250986
DOI: https://doi.org/10.1101/2021.02.02.21250986
Research output: Contribution to Journal › Article (E-pub ahead of print)
Three major dimensions of human brain cortical ageing in relation to cognitive decline across the eighth decade of life (12 pages) 4 Jan 2021 In: Molecular Psychiatry
DOI: https://doi.org/10.1038/s41380-020-00975-1
Research output: Contribution to Journal › Article (E-pub ahead of print)
Association of common genetic variants with brain microbleeds: A genome-wide association study 15 Dec 2020 In: Neurology, vol. 95, pp. e3331-e3343
DOI: https://doi.org/10.1212/WNL.0000000000010852
Research output: Contribution to Journal › Article (Published)
Brain network reorganisation and spatial lesion distribution in systemic lupus erythematosus 13 Dec 2020 In: Lupus
DOI: https://doi.org/10.1177/0961203320979045
Research output: Contribution to Journal › Article (Published)
Cerebral small vessel disease genomics and its implications across the lifespan 8 Dec 2020 In: Nature Communications
DOI: https://doi.org/10.1038/s41467-020-19111-2
Research output: Contribution to Journal › Article (E-pub ahead of print)

View all 294 publications on Research Explorer

This article was published on 11 Jun, 2021