Dr Mark Bastin
Reader
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities
In:
Stroke
DOI: https://doi.org/10.1161/STROKEAHA.119.027544
Research output: Contribution to Journal › Article (Published) -
Aging-sensitive networks within the human structural connectome are implicated in late-life cognitive declines.
In:
Biological Psychiatry
DOI: https://doi.org/10.1016/j.biopsych.2020.06.010
Research output: Contribution to Journal › Article (Accepted/In press) -
Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3
In:
European Stroke Journal, pp. 239698732092961
DOI: https://doi.org/10.1177/2396987320929617
Research output: Contribution to Journal › Article (Published) -
Evolution of white matter damage in amyotrophic lateral sclerosis
In:
Annals of Clinical and Translational Neurology
DOI: https://doi.org/10.1002/acn3.51035
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study: A multi-cohort study
In:
Frontiers in psychiatry, vol. 11
DOI: https://doi.org/10.3389/fpsyt.2020.00342
Research output: Contribution to Journal › Article (Published)