Dr Mark Bastin
Reader
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Birth weight is associated with brain tissue volumes seven decades later but not with MRI markers of brain ageing
In:
NeuroImage: Clinical
Research output: Contribution to Journal › Article (Accepted/In press) -
Early life predictors of late life cerebral small vessel disease in four prospective cohort studies
In:
Brain
Research output: Contribution to Journal › Article (Accepted/In press) -
Relationship between inferior frontal sulcal hyperintensities on brain MRI, ageing and cerebral small vessel disease
In:
Neurobiology of Aging, vol. 106, pp. 130-138
DOI: https://doi.org/10.1016/j.neurobiolaging.2021.06.013
Research output: Contribution to Journal › Article (Published) -
Cerebral Small Vessel Disease Burden and Longitudinal Cognitive Decline from age 73 to 82: the Lothian Birth Cohort 1936
In:
Translational Psychiatry
Research output: Contribution to Journal › Article (Accepted/In press) -
Comparison of structural MRI brain measures between 1.5 and 3T: Data from the Lothian Birth Cohort 1936
In:
Human Brain Mapping
DOI: https://doi.org/10.1002/hbm.25473
Research output: Contribution to Journal › Article (E-pub ahead of print)