Dr Mark Bastin
Reader
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Strong intercorrelations among global graph-theoretic indices of structural connectivity in the human brain
In:
NeuroImage, vol. 275
DOI: https://doi.org/10.1016/j.neuroimage.2023.120160
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
(13 pages)
In:
Nature Medicine, vol. 29, pp. 950-962
DOI: https://doi.org/10.1038/s41591-023-02268-w
Research output: Contribution to Journal › Article (Published) -
Predicting sex, age, general cognition and mental health with machine learning on brain structural connectomes
(21 pages)
In:
Human Brain Mapping, vol. 44, pp. 1913-1933
DOI: https://doi.org/10.1002/hbm.26182
Research output: Contribution to Journal › Article (Published) -
Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders
(17 pages)
In:
Brain, Behavior, and Immunity, vol. 110, pp. 322-338
DOI: https://doi.org/10.1016/j.bbi.2023.03.011
Research output: Contribution to Journal › Article (Published) -
Sleep quality, perivascular spaces and brain health markers in ageing - A longitudinal study in the Lothian Birth Cohort 1936
In:
Sleep medicine
DOI: https://doi.org/10.1016/j.sleep.2023.03.016
Research output: Contribution to Journal › Article (E-pub ahead of print)