Dr Mark Bastin
Reader

- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Genetic variants associated with longitudinal changes in brain structure across the lifespan
In:
Nature Neuroscience, vol. 25, pp. 421-432
DOI: https://doi.org/10.1038/s41593-022-01042-4
Research output: Contribution to Journal › Article (E-pub ahead of print) -
General factors of white matter microstructure from DTI and NODDI in the developing brain
In:
NeuroImage, pp. 119169
DOI: https://doi.org/10.1016/j.neuroimage.2022.119169
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Mediterranean-type diet and brain structural change from 73 to 79 years in the Lothian Birth Cohort 1936
In:
Journal of Nutrition, Health and Aging
Research output: Contribution to Journal › Article (Accepted/In press) -
Blood-based epigenome-wide analyses of cognitive abilities
In:
Genome Biology, vol. 23
DOI: https://doi.org/10.1186/s13059-021-02596-5
Research output: Contribution to Journal › Article (Published) -
Early life predictors of late life cerebral small vessel disease in four prospective cohort studies
In:
Brain, vol. 144
DOI: https://doi.org/10.1093/brain/awab331
Research output: Contribution to Journal › Article (Published)