Dr Mark Bastin
Reader
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: 0131 537 2511
- Email: Mark.Bastin@ed.ac.uk
Research summary
My research uses diffusion and structural MRI to investigate the connectivity of cerebral white matter, the brain’s wiring, and its relationship to cognitive ability in both health and disease.
Current areas of interest include normal ageing, preterm birth, motor neurone disease, MS, schizophrenia and bipolar disorder.
Collaborations stretch across the University and include psychologists, psychiatrists, neurologists, neonatologist and informaticians.
Research aims and areas of interest
My primary research interest is in the development of MRI acquisition methods and image processing techniques and their application to the study of white matter in the brain. Specific areas of interest include:
- Diffusion magnetic resonance imaging and tractography
- Magnetization transfer magnetic resonance imaging
- Quantitative spin-lattice relaxation (T1) measurement
- Application to normal ageing, preterm birth, brain tumours, MND, MS, schizophrenia and bipolar disorder
Affiliated research centres
-
Longitudinal microstructural MRI markers of demyelination and neurodegeneration in early relapsing-remitting multiple sclerosis: Magnetisation transfer, water diffusion and g-ratio
In:
NeuroImage: Clinical, vol. 36, pp. 103228
DOI: https://doi.org/10.1016/j.nicl.2022.103228
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Associations of Peak-Width Skeletonized Mean Diffusivity and Post-Stroke Cognition
In:
Life, vol. 12, pp. 1362
DOI: https://doi.org/10.3390/life12091362
Research output: Contribution to Journal › Article (Published) -
Topological relationships between perivascular spaces and progression of white matter hyperintensities: A pilot study in a sample of the Lothian Birth Cohort 1936
In:
Frontiers in Neurology, vol. 13
DOI: https://doi.org/10.3389/fneur.2022.889884
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI
In:
Brain
DOI: https://doi.org/10.1093/brain/awac290
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Assessment of perivascular space filtering methods using a three-dimensional computational model
In:
Magnetic Resonance Imaging, vol. 93, pp. 33-51
DOI: https://doi.org/10.1016/j.mri.2022.07.016
Research output: Contribution to Journal › Article (E-pub ahead of print)