Kristin Nicodemus
Chancellor's Fellow / Senior Lecturer
- Usher Institute
- College of Medicine and Veterinary Medicine
Contact details
Address
- Street
-
Usher Institute – University of Edinburgh
Old Medical School
Teviot Place - City
- Edinburgh
- Post code
- EH8 9AG
Background
I am a Chancellor's Fellow and Senior Lecturer within the Usher Institute. My group studies the genomic architecture of Psychiatric disorders, particularly schizophrenia, major depressive disorder (MDD) and bipolar disorder. To unravel the complex genomics of risk in high-dimensional data I develop and apply machine learning and other statistical algorithms to detect single genes of major effect along with polygenic and epistatic components.
I completed a Ph.D. in Statistical Genetics at the Johns Hopkins School of Public Health (Baltimore, USA) in 2007 whilst simultaneously working with Dr. Daniel Weinberger in the Genes, Cognition and Psychosis Program at the National Institute of Mental Health, NIH (2004-2007). I then undertook training in population and statistical genetics at the University of Oxford before obtaining a prestigious Science Foundation Ireland Starting Investigator Research Grant in 2012 to focus on machine learning approaches for data integration and epistasis detection in schizophrenia at Trinity College Dublin.
Employment: 2004-2007: Statistical Geneticist, Genes, Cognition and Psychosis Program, National Institute of Mental Health, NIH, USA 2007-2010: Postdoctoral Fellow, Department of Clinical Pharmacology, University of Oxford, UK 2010-2012: Career Development Fellow, Department of Anatomy, Physiology and Genetics, University of Oxford, UK 2012-2014: Science Foundation Ireland Starting Researcher, Department of Psychiatry, Trinity College Dublin, Ireland 2014-current: Chancellor's Fellow/Senior Lecturer and Group Leader, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh
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The role of neuroticism in self-harm and suicidal ideation: Results from two UK population-based cohorts
In:
Social psychiatry and psychiatric epidemiology, vol. 54, pp. 1505-1518
DOI: https://doi.org/10.1007/s00127-019-01725-7
Research output: Contribution to Journal › Article (Published) -
A major role for common genetic variation in anxiety disorders
In:
Molecular Psychiatry
DOI: https://doi.org/10.1038/s41380-019-0559-1
Research output: Contribution to Journal › Article (Published) -
Distinct Prosodic Correlates for Nine Dimensions of Mental Health Symptoms
(5 pages)
Research output: Contribution to Conference › Conference contribution (Published) -
The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia
(8 pages)
In:
Neuropsychopharmacology, vol. 44, pp. 1562-1569
DOI: https://doi.org/10.1038/s41386-019-0410-z
Research output: Contribution to Journal › Article (Published) -
A review of neuroeconomic gameplay in psychiatric disorders
In:
Molecular Psychiatry
DOI: https://doi.org/10.1038/s41380-019-0405-5
Research output: Contribution to Journal › Review article (E-pub ahead of print)