Dr Katie Marwick
Clinical Lecturer in Psychiatry
- Centre for Discovery Brain Sciences
- Division of Psychiatry
- Centre for Clinical Brain Sciences
Contact details
- Email: katie.marwick@ed.ac.uk
Background
Dr Katie Marwick studied medicine at the University of Cambridge and University of Edinburgh, before training in Psychiatry in south east Scotland. She completed a Wellcome Trust funded PhD via the Edinburgh Clinical Academic Track scheme in 2016.
She is currently a CSO/NES Clinical Lecturer in Psychiatry and Honorary Registrar in Psychiatry with NHS Lothian, specialising in General Adult Psychiatry and Perinatal Psychiatry.
Qualifications
MA MBChB MRCPsych PhD
Undergraduate teaching
I created and lead the team that prepares the Objective Structured Clinical Exams (OSCEs) in Psychiatry for year 5 medical students.
I am author of a popular undergraduate textbook, "Crash Course in Psychiatry" (4th and 5th editions) and faculty advisor for the 6th edition.
I have supervised honours projects in neuroscience.
Open to PhD supervision enquiries?
Yes
Current PhD students supervised
I am co-supervisor for an Epilepsy Research UK funded PhD studentship investigating the role of the NMDA receptor GluN2A subunit in childhood-onset epilepsy, working with student Yaseen Almeerali and Prof David Wyllie.
Research summary
My over-arching interest is the pathogenesis of severe mental disorder. My PhD and post-doctoral work focused on investigating the functional consequences of disease-associated variants in NMDA receptors. I am now exploring the impact of reproductive hormones on women's mental health problems, particularly severe perinatal mental illness and exacerbations of bipolar and psychosis at times of hormonal fluctuation. Currently I am working with routinely collected health care records to identify comorbidities of postpartum psychosis.
Research interests and experience:
- Postpartum psychosis
- Perinatal psychiatry
- Bipolar affective disorder
- NMDA receptors
- Genetics
- Electrophysiology
- Data science
-
Pathway-based polygenic risk scores for schizophrenia and associations with reported psychotic-like experiences and neuroimaging phenotypes in UK Biobank
In:
Biological psychiatry global open science
DOI: https://doi.org/10.1016/j.bpsgos.2023.03.004
Research output: Contribution to Journal › Article (Published) -
Providing Home Treatment for Acute Mental Illness During the COVID-19 Pandemic
In:
Psychiatric Services
DOI: https://doi.org/10.1176/appi.ps.202100269
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Dialysis and plasmapheresis for schizophrenia: a systematic review
In:
Psychological Medicine, pp. 1-8
DOI: https://doi.org/10.1017/S0033291720001324
Research output: Contribution to Journal › Article (Published) -
The human NMDA receptor GluN2AN615K variant influences channel blocker potency
In:
Pharmacology Research and Perspectives, vol. 7
DOI: https://doi.org/10.1002/prp2.495
Research output: Contribution to Journal › Article (Published) -
GRIN2A-related disorders: genotype and functional consequence predict phenotype
(13 pages)
In:
Brain, vol. 142, pp. 80–92
DOI: https://doi.org/10.1093/brain/awy304
Research output: Contribution to Journal › Article (Published) -
Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy
In:
The Journal of Physiology
DOI: https://doi.org/10.1113/JP277292
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Crash Course in Psychiatry (5th Edition)
Research output: › Book (Published) -
The developmental shift of NMDA receptor composition proceeds independently of GluN2 subunit-specific GluN2 C-terminal sequences
In:
Cell Reports, vol. 25, pp. 841-851.e4
DOI: https://doi.org/10.1016/j.celrep.2018.09.089
Research output: Contribution to Journal › Article (E-pub ahead of print) -
The Application of N-of-1 Treatment Trials in Schizophrenia: A Systematic Review
In:
The British Journal of Psychiatry
DOI: https://doi.org/10.1192/bjp.2018.71
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Transfection in primary cultured neuronal cells
DOI: https://doi.org/10.1007/978-1-4939-7321-7_6
Research output: › Chapter (E-pub ahead of print) -
Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1
(13 pages)
In:
eLIFE, vol. 2017
DOI: https://doi.org/10.7554/eLife.17161
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Functional assessment of the NMDA receptor variant GluN2A (R586K)
In:
Wellcome Open Research , vol. 2, pp. 20
DOI: https://doi.org/10.12688/wellcomeopenres.10985.2
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers
In:
Organic & Biomolecular chemistry
DOI: https://doi.org/10.1039/c6ob02796b
Research output: Contribution to Journal › Article (Published) -
Acute Liver Failure
Research output: › Chapter (peer-reviewed) (Published) -
Effect of a GRIN2A de novo mutation associated with epilepsy and intellectual disability on NMDA receptor currents and Mg(2+) block in cultured primary cortical neurons
In:
The Lancet, vol. 385 Suppl 1, pp. S65
DOI: https://doi.org/10.1016/S0140-6736(15)60380-4
Research output: Contribution to Journal › Meeting abstract (Published) -
Sensitivity to cuteness in baby faces is not influenced by pregnancy
(1 page)
In:
The Lancet, vol. 381, pp. 72-72
Research output: Contribution to Journal › Meeting abstract (Published) -
Crash Course Psychiatry (4th edition)
Research output: › Book (Published) -
Antipsychotics and abnormal liver function tests: systematic review.
(9 pages)
In:
Clinical Neuropharmacology, pp. 244-53
Research output: Contribution to Journal › Article (Published) -
Social cognition, the male brain and the autism spectrum
In:
PLoS ONE, vol. 7, pp. e49033
DOI: https://doi.org/10.1371/journal.pone.0049033
Research output: Contribution to Journal › Article (Published) -
Hippocampal function in schizophrenia and bipolar disorder
(10 pages)
In:
Psychological Medicine, vol. 40, pp. 761-770
DOI: https://doi.org/10.1017/S0033291709991000
Research output: Contribution to Journal › Article (Published)