Dr Georg Kustatscher
Research Group Leader
- Institute of Quantitative Biology, Biochemistry and Biotechnology
- School of Biological Sciences
Contact details
- Email: georg.kustatscher@ed.ac.uk
Address
- Street
-
4.15 Michael Swann Building
King's Buildings
Max Born Crescent - City
- Edinburgh
- Post code
- EH9 3BF
Background
Dr Kustatscher is a Group leader and MRC Career Development Fellow at the Insitute for Quantitative Biology, Biochemistry and Biotechnology, Edinburgh.
He studied Molecular Biology at the University of Salzburg, Austria, and obtained a PhD from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, working on epigenetics in the lab of Andreas Ladurner.
From 2008 to 2020 he was a Postdoc in Juri Rappsilber’s group at the Wellcome Centre for Cell Biology (WCB) in Edinburgh, combining proteomics and computational approaches to understand how cells regulate mRNA and protein levels from a systems perspective.
Research summary
Systems Biology
Proteomics
Computational Biology
Integration of "omics" data
Current research interests
The aim of my lab is to understand how cells regulate protein levels, and how these processes are disrupted in cancer cells. We address this question by combining proteomics, transcriptomics and computational approaches, including machine-learning.Current project grants
How cells regulate protein levels (and fail to do so in cancer)
Medical Research Council (MRC) Career Development Award
Grant number: MR/T03050X/1
-
The proteomic landscape of genome-wide genetic perturbations
(39 pages)
In:
Cell, vol. 186
DOI: https://doi.org/10.1016/j.cell.2023.03.026
Research output: Contribution to Journal › Article (Published) -
Higher‐order modular regulation of the human proteome
(14 pages)
In:
Molecular Systems Biology
DOI: https://doi.org/10.15252/msb.20209503
Research output: Contribution to Journal › Article (Published) -
Mass spectrometry-based high-throughput proteomics and its role in biomedical studies and systems biology
(15 pages)
In:
Proteomics
DOI: https://doi.org/10.1002/pmic.202200013
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
An open invitation to the understudied proteins initiative
(3 pages)
In:
Nature Biotechnology, vol. 40, pp. 815-817
DOI: https://doi.org/10.1038/s41587-022-01316-z
Research output: Contribution to Journal › Letter (Published) -
Understudied proteins: Opportunities and challenges for functional proteomics
(6 pages)
In:
Nature Methods, vol. 19, pp. 774-779
DOI: https://doi.org/10.1038/s41592-022-01454-x
Research output: Contribution to Journal › Comment/debate (E-pub ahead of print)