Dr Christopher W. Wood

Lecturer in Biotechnology

School of Biological Sciences

Email: chris.wood@ed.ac.uk
Web: Group Website

Street: Room 1.68
Roger Land Building
King's Buildings
City: Edinburgh
Post code: EH9 3JQ

Biography

Background

2020 Lecturer in Biotechnology, University of Edinburgh

2018 EPSRC Postdoctoral Research Fellow, University of Edinburgh

2016 Postdoctoral Researcher, Woolfson Group, University of Bristol

Qualifications

2016 DPhil. Biochemistry, University of Bristol

2013 BSc. (Hons) Molecular and Cellular Biology, University of Glasgow

Research

Research summary

Protein design, protein structure, structural bioinformatics, machine learning, experimental automation.

Publications

Differential sensing with arrays of de novo designed peptide assemblies (12 pages) 24 Jan 2023 In: Nature Communications, vol. 14
DOI: https://doi.org/10.1038/s41467-023-36024-y
Research output: Contribution to Journal › Article (Published)
Generation of photocaged nanobodies for intracellular applications in an animal using genetic code expansion and computationally guided protein engineering** (11 pages) 18 Aug 2022 In: ChemBioChem, vol. 23
DOI: https://doi.org/10.1002/cbic.202200321
Research output: Contribution to Journal › Article (Published)
DE-STRESS: A user-friendly web application for the evaluation of protein designs (6 pages) 15 Dec 2021 In: Protein Engineering, Design & Selection (PEDS), vol. 34
DOI: https://doi.org/10.1093/protein/gzab029
Research output: Contribution to Journal › Article (Published)
PDBench: Evaluating Computational Methods for Protein Sequence Design (20 pages) 16 Sep 2021
Research output: › Preprint (Published)
De novo designed peptide and protein hairpins self‐assemble into sheets and nanoparticles (11 pages) 15 Feb 2021 In: Small
DOI: https://doi.org/10.1002/smll.202100472
Research output: Contribution to Journal › Article (E-pub ahead of print)
BAlaS: Fast, interactive and accessible computational alanine-scanning using BudeAlaScan 1 May 2020 In: Bioinformatics, vol. 36, pp. 2917-2919
DOI: https://doi.org/10.1093/bioinformatics/btaa026
Research output: Contribution to Journal › Article (Published)
Peptide assembly directed and quantified using megadalton DNA nanostructures (9 pages) 24 Sep 2019 In: ACS Nano, vol. 13, pp. 9927-9935
DOI: https://doi.org/10.1021/acsnano.9b04251
Research output: Contribution to Journal › Article (Published)
Navigating the structural landscape of de Novo α-helical bundles (11 pages) 5 Jun 2019 In: Journal of the American Chemical Society, vol. 141, pp. 8787-8797
DOI: https://doi.org/10.1021/jacs.8b13354
Research output: Contribution to Journal › Article (Published)
Maintaining and breaking symmetry in homomeric coiled-coil assemblies 1 Dec 2018 In: Nature Communications, vol. 9
DOI: https://doi.org/10.1038/s41467-018-06391-y
Research output: Contribution to Journal › Article (Published)
Applying graph theory to protein structures: An atlas of coiled coils (8 pages) 1 Oct 2018 In: Bioinformatics, vol. 34, pp. 3316-3323
DOI: https://doi.org/10.1093/bioinformatics/bty347
Research output: Contribution to Journal › Article (Published)
Chimeric streptavidins as host proteins for artificial metalloenzymes (9 pages) 2 Feb 2018 In: ACS Catalysis, vol. 8, pp. 1476-1484
DOI: https://doi.org/10.1021/acscatal.7b03773
Research output: Contribution to Journal › Article (Published)
CCBuilder 2.0: Powerful and accessible coiled-coil modeling (9 pages) 1 Jan 2018 In: Protein Science, vol. 27, pp. 103-111
DOI: https://doi.org/10.1002/pro.3279
Research output: Contribution to Journal › Article (Published)
ISAMBARD: An open-source computational environment for biomolecular analysis, modelling and design (8 pages) 5 Jun 2017 In: Bioinformatics, vol. 33, pp. 3043-3050
DOI: https://doi.org/10.1093/bioinformatics/btx352
Research output: Contribution to Journal › Article (Published)
De novo protein design: How do we expand into the universe of possible protein structures? (11 pages) 1 Aug 2015 In: Current opinion in structural biology, vol. 33, pp. 16-26
DOI: https://doi.org/10.1016/j.sbi.2015.05.009
Research output: Contribution to Journal › Review article (Published)
Modular design of self-assembling peptide-based nanotubes (9 pages) 28 Jul 2015 In: Journal of the American Chemical Society, vol. 137, pp. 10554-10562
DOI: https://doi.org/10.1021/jacs.5b03973
Research output: Contribution to Journal › Article (Published)
Computational design of water-soluble α-helical barrels (4 pages) 24 Oct 2014 In: Science, vol. 346, pp. 485-488
DOI: https://doi.org/10.1126/science.1257452
Research output: Contribution to Journal › Article (Published)
CCBuilder: An interactive web-based tool for building, designing and assessing coiled-coil protein assemblies (7 pages) 26 Jul 2014 In: Bioinformatics, vol. 30, pp. 3029-3035
DOI: https://doi.org/10.1093/bioinformatics/btu502
Research output: Contribution to Journal › Article (Published)

View all 17 publications on Research Explorer

This article was published on 1 Oct, 2023