Dr Atlanta G. Cook

Wellcome Senior Research Fellow

Background

WT Senior Research Fellow at Wellcome Trust centre for Cell Biology in Edinburgh (2016-present)

MRC career development Fellow at Wellcome Trust centre for Cell Biology in Edinburgh (2011-2016)

Postdoctoral research Fellow, MPI for biochemistry in Martinsried, Germany (2007-2010)

Postdoctoral Research Fellow  EMBL Heidelberg, Germany (2004-2007)

Qualifications

DPhil, Biochemistry, Oxford University (1999-2003)

MBiochemistry, Oxford University (1995-1999)

Research summary

The expression of individual genes is controlled at the levels of mRNA transcription and also post-transcriptionally, by processes such as splicing, localization, modification or editing, and degradation. To gain a mechanistic understanding of these processes it is important to understand the interactions between the individual players, including both protein and nucleic acid components, at the molecular level. We have used structural approaches to tackle mechanistic questions about how protein-RNA interactions can control RNA maturation and RNA editing and how transcriptional repressors are recruited to methylated DNA. By combining structural studies with biochemical, biophysical and cell-based functional assays we can gain powerful insights into these molecular processes.

View all 21 publications on Research Explorer