Dr Adam Balic
Roslin Research Fellow

Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Background
Dr Balic received degree in microbiology from Monash University, Melbourne, Australia. He followed this with a PhD in Veterinary science from the University of Melbourne, Australia, studying the immunobiology of gastrointestinal nematode infections in sheep. He joined Prof. Rick Maizels’ lab at the University of Edinburgh, where he was involved in dissecting how the gastrointestinal nematode Nippostrongylus brasiliensis drives Th2 responses in mice, via the dendritic cell population. Dr Balic then joined the Roslin Institute as a research fellow, where he has produced several lines of transgenic chickens for immunological studies in chickens. Dr Balic has recently been appointed as a career track fellow at the Roslin Institute.
Research summary
Defining the molecular and cellular mechanisms that underpin lymphoid organ development in chickens. Developing and exploiting novel gene transfer and editing technologies in order to visualise and manipulate specific chicken immune cell populations.
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Development of novel reagents to chicken FLT3, XCR1 and CSF2R for the identification and characterisation of avian conventional dendritic cells
In:
Immunology
DOI: https://doi.org/10.1111/imm.13426
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
In:
Nature Communications, vol. 12
DOI: https://doi.org/10.1038/s41467-021-23143-7
Research output: Contribution to Journal › Article (Published) -
Characterization of conventional dendritic cells and macrophages in the spleen using the CSF1R-reporter transgenic chickens
In:
Frontiers in Immunology
DOI: https://doi.org/10.3389/fimmu.2021.636436
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system
In:
Developmental and Comparative Immunology
DOI: https://doi.org/10.1016/j.dci.2019.103586
Research output: Contribution to Journal › Article (Published) -
Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program
In:
Cell, vol. 179, pp. 1609-1622.e16
DOI: https://doi.org/10.1016/j.cell.2019.11.010
Research output: Contribution to Journal › Article (Published) -
Antigen sampling CSF1R-expressing epithelial cells are the functional equivalents of mammalian M cells in the avian follicle-associated epithelium
In:
Frontiers in Immunology, vol. 10
DOI: https://doi.org/10.3389/fimmu.2019.02495
Research output: Contribution to Journal › Article (Published) -
Characterization of Subpopulations of Chicken Mononuclear Phagocytes That Express TIM4 and CSF1R
In:
Journal of Immunology, vol. 202, pp. 1186-1199
DOI: https://doi.org/10.4049/jimmunol.1800504
Research output: Contribution to Journal › Article (Published) -
Visualisation and characterisation of mononuclear phagocytes in the chicken respiratory tract using CSF1R-transgenic chickens
In:
Veterinary Research, vol. 49
DOI: https://doi.org/10.1186/s13567-018-0598-7
Research output: Contribution to Journal › Article (Published) -
Intraganglionic macrophages: a new population of cells in the enteric ganglia
In:
Journal of Anatomy, vol. 233, pp. 401-410
DOI: https://doi.org/10.1111/joa.12863
Research output: Contribution to Journal › Article (Published) -
Illuminating the chicken model through genetic modification
In:
International Journal of Developmental Biology, vol. 62, pp. 257-264
DOI: https://doi.org/10.1387/ijdb.170323mm
Research output: Contribution to Journal › Article (Published)